Asymmetry Synthesis: Topics, Advances and Applications
A special issue of Symmetry (ISSN 2073-8994). This special issue belongs to the section "Chemistry: Symmetry/Asymmetry".
Deadline for manuscript submissions: 31 July 2024 | Viewed by 466
Special Issue Editors
Interests: synthesis; inorganic synthesis; organic synthesis; chemical synthesis
Special Issue Information
Dear Colleagues,
As Morrison and Mosher put it, ‘asymmetric synthesis’ is the transformation of an achiral unit present in a group of substrate molecules into a chiral unit in a way that yields asymmetric amounts of stereoisomers. Therefore, any synthetic procedure wherein one or more additional chiral components are introduced during a functional group transition is considered to be an example of asymmetric synthesis, wherein the reactions employed are highly enantiospecific. Single enantiomer synthesis of chiral compounds is crucial because biological systems, where such type of compounds are utilized, are themselves chiral. Distinct enantiomers have been shown to have notably varied interactions with their respective target biological receptors, and consequently, to elicit a wide range of different effects. The necessity for enantiomerically pure pharmaceuticals and agricultural chemicals is supported by arguments from economics, ecology, and pharmacodynamics, thereby making asymmetric synthesis an area of intense study in both academic and industrial facilities around the world. For instance, the embracement of asymmetric ‘click’ for the synthesis of chiral drug-like molecules with potent biological activity has progressively increased in recent years.
This Special Issue will be focused on the comprehensive idea of ‘asymmetric synthesis’, with in-depth discussion related to the latest approaches made in the field that have been extensively searched for applications in modern day research areas, including but not limited to pharmaceuticals, natural product chemistry, nanomaterials, etc.
Dr. Jandeep Singh
Dr. Manisha Singh
Guest Editors
Manuscript Submission Information
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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- the design of asymmetric synthesis
- stereoselective catalysis
- chirality
- chiral auxiliaries
- asymmetric transfigurations
- metal catalysed asymmetric synthesis
- chiral ‘click’ building blocks
- asymmetric click
- application in nanomedicine
- material sciences
- novel catalysts for asymmetric synthesis
