Extraction and Component Analysis of Active Ingredients from Natural Products

A special issue of Separations (ISSN 2297-8739). This special issue belongs to the section "Analysis of Natural Products and Pharmaceuticals".

Deadline for manuscript submissions: closed (30 June 2023) | Viewed by 3105

Special Issue Editor


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Guest Editor
Department of Chemistry, Government College University Faisalabad, Faisalabad 38000, Pakistan
Interests: natural dyes; green chemistry; plant pigments; green extraction

Special Issue Information

Dear Colleagues,

Sustainability is currently the world’s most demanding matter in various fields. To meet this demand, natural products are one of the best and most suitable options for all fields, particularly pharmaceuticals, food, flavors, fashion, textiles, perfumes, etc. The recent COVID-19 scenario has also forced all research organizations to move towards natural products. Nowadays, natural products with excellent anti-viral, anti-microbial, anti-cancer, antioxidant, and other ayurvedic properties are favored. Hence, for their characterization and possible application, the world is now reviving their potential application for all fields. For the extraction of natural products, some conventional methods are used, but now modern approaches such as radiation techniques have been adopted on account of their cost, energy, and time-effective nature. Thus, in view of recent demands and global health all around the world, the Special Issue for studies on the extraction and compound analysis of potential bio-actives has been introduced. This Special Issue aims to introduce herbal products with sustainable and green techniques for all walks of life.

Dr. Shahid Adeel
Guest Editor

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Keywords

  • natural products
  • green extraction
  • active ingredient
  • composition analysis

Published Papers (2 papers)

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Research

12 pages, 1272 KiB  
Article
GC-MS Analysis and Bioactivity Screening of Leaves and Fruits of Zanthoxylum armatum DC.
by Jie Ma, Liping Ning, Jingyan Wang, Wei Gong, Yue Gao and Mei Li
Separations 2023, 10(8), 420; https://doi.org/10.3390/separations10080420 - 25 Jul 2023
Cited by 1 | Viewed by 1199
Abstract
Zanthoxylum armatum DC. is a plant that has been homologated for medicine and food by the Chinese for three thousand years. In this study, the essential oils of fresh leaves and fruits were extracted by hydrodistillation, the aromas of fresh leaves and fruits [...] Read more.
Zanthoxylum armatum DC. is a plant that has been homologated for medicine and food by the Chinese for three thousand years. In this study, the essential oils of fresh leaves and fruits were extracted by hydrodistillation, the aromas of fresh leaves and fruits were extracted by headspace solid-phase microextraction and their chemical compositions were analyzed by gas chromatography mass spectrometry. The main components of the leaf essential oils were linalool (62.01%), 2-undecanone (9.83%) and 2-tridecanone (5.47%); the fruit essential oils were linalool (72.17%), limonene (8.05%) and sabinene (6.77%); the leaf aromas were limonene (39.15%), β-myrcene (15.8%), sabinene (8.17%) and linalool (5.25%); the fruit aromas were limonene (28.43%), sabinene (13.56%), linalool (11.47%) and β-myrcene (8.64%). By comparison, it was found that the composition of leaf essential oils and fruit essential oils were dominated by oxygenated monoterpenes, while the composition of their aromas were both dominated by monoterpenes; the relative content of non-terpene components in leaf essential oil and leaf aroma is second only to oxygenated monoterpenes, while their content in fruits is low; the chemical composition of leaf aromas and fruit aromas were richer than those of essential oils. In this study, we reported for the first time that the antitumor, tyrosinase inhibition, HMGR inhibition and nitric oxide production inhibition activity of leaf essential oils were stronger than those of fruit essential oils in in vitro tests. The results of the study can provide a reference for the recycling and green low-carbon transformation of the leaves, and also help to deepen the understanding of the value of the volatile chemical constituents of this plant in “forest medicine” or “aromatherapy”, and provide new ideas for the transformation of the value of the plant in the secondary and tertiary industry chain. Full article
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14 pages, 2051 KiB  
Article
Sustainable Microwave-Assisted Extraction of Santalin from Red Sandal Wood Powder (Ptrecarpus santalinus) for Bio-Coloration of Mordanted Silk Fabric
by Samra Barkaat, Maria Mehboob, Shahid Adeel, Fazal-ur-Rehman, Nimra Amin, Noman Habib and Mozhgan Hosseinnezhad
Separations 2023, 10(2), 118; https://doi.org/10.3390/separations10020118 - 07 Feb 2023
Cited by 9 | Viewed by 1497
Abstract
The coloring behavior of santalin, a natural reddish-brown dye derived from sandalwood, has been investigated in this work for the dyeing of silk fabrics while being heated in MW radiation. Microwave (MW) radiation up to 5 min has been employed to isolate colorant [...] Read more.
The coloring behavior of santalin, a natural reddish-brown dye derived from sandalwood, has been investigated in this work for the dyeing of silk fabrics while being heated in MW radiation. Microwave (MW) radiation up to 5 min has been employed to isolate colorant (Santalin) from red sandalwood (Ptrecarpus santalinus) in selected medium, and bio-mordants in competing with salts as chemical-mordants have been included. Statistical analysis was made and dyeing variables were selected for getting dark shades though mordants. MW treatment for 3 min. to both extract and fabric was selected and mild dyeing conditions were optimized statistically to get dark shades. On applying chemical mordants, selected amount of salts of Al+3, Fe+2 and T.A. before and after dyeing, has given good results. Comparatively, selected extracts of plant based sources have shown colorfast shades of high strength. The MW radiation has excellent potential to extract dye form plants using optimum medium through less time and energy, and the application of plant extracts along with sustainable salts have developed colorfast shades. Full article
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