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Sensors for Detection of Cancer Biomarkers
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Sensors for Detection of Cancer Biomarkers

A special issue of Sensors (ISSN 1424-8220). This special issue belongs to the section "Biomedical Sensors".

Deadline for manuscript submissions: closed (30 November 2022) | Viewed by 4909

Special Issue Editor

Prof. Dr. Hai-Feng (Frank) Ji

E-Mail Website
Guest Editor
Department of Chemistry, Drexel University, 3141 Chestnut Street, Disque 507, Philadelphia, PA 19104, USA
Interests: MEMS; microcantilever; FET; fluorescent; polythiophene; polyaniline; hydrogel; nanocomposites
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Cancer mortality rates have dropped considerably in the last three decades, largely because of the early detection of cancers. More indicators for the early stage of cancers are needed in order to continue to improve the accuracy, to lower the detection limit, and to expand the early detection of more types of cancers, so the cancers can be treated at their earliest stages.

I would like to invite you to submit either original articles or review papers on sensors and methods for cancer biomarkers detection. The Special Issue particularly welcomes but is not limited to topics listed in the following keywords.

Dr. Hai-Feng (Frank) Ji
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Sensors is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • Cancer biomarker
  • Artificial intelligence
  • Spectroscopy
  • Antibody
  • Aptamer
  • DNA
  • RNA
  • Nanomaterials
  • Biosensors
  • Wireless biosensors
  • Healthcare
  • Lab-on-Chip
  • Clinical analysis
  • Point-of-care
  • Cell phone-based sensors
  • Genetic testing
  • Liquid biopsy tests
  • Population-science-based testing

Published Papers (2 papers)

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15 pages, 1183 KiB  
Review
The Influence of Mechanical Bowel Preparation on Volatile Organic Compounds for the Detection of Gastrointestinal Disease—A Systematic Review
by Ashwin Krishnamoorthy, Subashini Chandrapalan, Sofie Bosch, Ayman Bannaga, Nanne K.H. De Boer, Tim G.J. De Meij, Marcis Leja, George B. Hanna, Nicoletta De Vietro, Donato Altomare and Ramesh P. Arasaradnam
Sensors 2023, 23(3), 1377; https://doi.org/10.3390/s23031377 - 26 Jan 2023
Cited by 3 | Viewed by 1630
Abstract
(1) Background: Colorectal cancer is the second commonest cause of cancer deaths worldwide; recently, volatile organic compounds (VOCs) have been proposed as potential biomarkers of this disease. In this paper, we aim to identify and review the available literature on the influence of [...] Read more.
(1) Background: Colorectal cancer is the second commonest cause of cancer deaths worldwide; recently, volatile organic compounds (VOCs) have been proposed as potential biomarkers of this disease. In this paper, we aim to identify and review the available literature on the influence of mechanical bowel preparation on VOC production and measurement. (2) Methods: A systematic search for studies was carried out for articles relevant to mechanical bowel preparation and its effects on volatile organic compounds. A total of 4 of 1349 papers initially derived from the search were selected. (3) Results: Two studies with a total of 134 patients found no difference in measured breath VOC profiles after bowel preparation; one other study found an increase in breath acetone in 61 patients after bowel preparation, but no other compounds were affected. Finally, the last study showed the alteration of urinary VOC profiles. (4) Conclusions: There is limited data on the effect of bowel preparation on VOC production in the body. As further studies of VOCs are conducted in patients with symptoms of gastrointestinal disease, the quantification of the effect of bowel preparation on their abundance is required. Full article
(This article belongs to the Special Issue Sensors for Detection of Cancer Biomarkers)
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10 pages, 1140 KiB  
Letter
AniScan Using Extracellular Cyclic AMP-Dependent Protein Kinase A as a Serum Biomarker Assay for the Diagnosis of Malignant Tumors in Dogs
by Ji-Eun Lee, Woo-Jin Song, Hunjoo Lee, Byung-Gak Kim, Taeho Kim, Changsun Lee, Bonghwan Jang, Hwa-Young Youn, Ul-Soo Choi and Dong-Ha Bhang
Sensors 2020, 20(15), 4075; https://doi.org/10.3390/s20154075 - 22 Jul 2020
Cited by 3 | Viewed by 2392
Abstract
The early detection of tumors improves chances of decreased morbidity and prolonged survival. Serum biomarkers are convenient to use and have several advantages over other approaches, such as accuracy and straightforward protocols. Reliable biomarkers from easily accessible sources are warranted for the development [...] Read more.
The early detection of tumors improves chances of decreased morbidity and prolonged survival. Serum biomarkers are convenient to use and have several advantages over other approaches, such as accuracy and straightforward protocols. Reliable biomarkers from easily accessible sources are warranted for the development of cost-effective assays for routine screening, particularly in veterinary medicine. Extracellular c-AMP-dependent protein kinase A (ECPKA) is a cytosolic leakage enzyme. The diagnostic accuracy of detecting autoantibodies against ECPKA was found to be higher than that of ECPKA activity from enzymatic assays, which use a complicated method. Here, we investigated the diagnostic significance of measuring serum ECPKA autoantibody levels using an in-house kit (AniScan cancer detection kit; Biattic, Anyang, Korea). We used sera from 550 dogs, including healthy dogs and those with malignant and benign tumors. Serum ECPKA and immunoglobulin G were determined using the AniScan cancer detection kit. ECPKA autoantibody levels were significantly higher (p < 0.01) in malignant tumors than in benign tumors, non-tumor diseases, and healthy controls. On the basis of sensitivity and specificity values, AniScan ECPKA is a rapid and easy-to-use assay that can be applied to screen malignant tumors from benign tumors or other diseases in dogs. Full article
(This article belongs to the Special Issue Sensors for Detection of Cancer Biomarkers)
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