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Sensors
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Point-of-Care Sensing Systems for Health Monitoring
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Point-of-Care Sensing Systems for Health Monitoring

A special issue of Sensors (ISSN 1424-8220). This special issue belongs to the section "Biomedical Sensors".

Deadline for manuscript submissions: closed (20 April 2022) | Viewed by 4150

Special Issue Editor

Prof. Dr. Kan Wang

E-Mail Website
Guest Editor
Department of Instrument Science and Engineering, School of Electronic Information and Electrical Engineering, Shanghai Jiao Tong University, Shanghai 200240, China
Interests: point-of-car testing(POCT); immunochromatography; magnetic immunoassay; microfluidic devices; nanobiosensors and nanotechnology used in biosensors

Special Issue Information

Dear Colleagues,

Point-of-care (POC) testing is an in vitro detection method that is able to obtain detection results instantly at the sampling site by utilizing rapid and convenient analytical instruments as well as supporting reagents. By collecting and analyzing samples such as whole blood, serum, urine, saliva, viruses, bacteria and other proteins, the POCT is capable of performing healthcare, disease management, therapy assistance and food safety monitoring in a hospital, clinic, doctor's office or at home. Accordingly, corresponding diagnostic platforms are required for the quantitative detection of analytes. These detection systems usually need to meet the following requirements: (a) rapid test process, (b) high accuracy and sensitivity, (c) simple to operate, (d) steady working conditions, and (e) automatic analysis and data transmission.

This Special Issue presents an interesting opportunity for researchers who work in the POC sensor field. We invite contributions to this Special Issue from different fields about sensor, biosensing for health monitoring. The list of potential topics is broad, but we are particularly interested in studies on the design, development, and applications of sensor based technologies in POC sensing. Topics include, but are not limited to, the following research areas:

  • Intelligent health-monitoring system
  • Sensor development and characteristics
  • Wearable sensors in medical health applications
  • Point-of-care testing devices, microdevices, nanodevices
  • MEMS sensors with sensing nanocomponents
  • Nanotechnology for on-chip biosensors
  • Nano-Magnetic sensor for device application

Prof. Dr. Kan Wang
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Sensors is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • Intelligent health-monitoring system
  • Sensor development and characteristics
  • Wearable sensors in medical health applications
  • Point-of-care testing devices, microdevices, nanodevices
  • MEMS sensors with sensing nanocomponents
  • Nanotechnology for on-chip biosensors
  • Nano-Magnetic sensor for device application

Published Papers (1 paper)

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Research

14 pages, 4209 KiB  
Article
Low-Cost, Real-Time Polymerase Chain Reaction System for Point-of-Care Medical Diagnosis
by Tchamie Kadja, Chengkun Liu, Yvonne Sun and Vamsy P. Chodavarapu
Sensors 2022, 22(6), 2320; https://doi.org/10.3390/s22062320 - 17 Mar 2022
Cited by 4 | Viewed by 3746
Abstract
Global health crises due to the prevailing Coronavirus Disease 2019 (COVID-19) pandemic have placed significant strain on health care facilities such as hospitals and clinics around the world. Further, foodborne and waterborne diseases are not only spreading faster, but also appear to be [...] Read more.
Global health crises due to the prevailing Coronavirus Disease 2019 (COVID-19) pandemic have placed significant strain on health care facilities such as hospitals and clinics around the world. Further, foodborne and waterborne diseases are not only spreading faster, but also appear to be emerging more rapidly than ever before and are able to circumvent conventional control measures. The Polymerase Chain Reaction (PCR) system is a well-known diagnostic tool for many applications in medical diagnostics, environmental monitoring, and food and water quality assessment. Here, we describe the design, development, and testing of a portable, low-cost, and real-time PCR system that can be used in emergency health crises and resource-poor situations. The described PCR system incorporates real-time reaction monitoring using fluorescence as an alternative to gel electrophoresis for reaction analysis, further decreasing the need of multiple reagents, reducing sample testing cost, and reducing sample analysis time. The bill of materials cost of the described system is approximately $340. The described PCR system utilizes a novel progressive selective proportional–integral–derivative controller that helps in reducing sample analysis time. In addition, the system employs a novel primer-based approach to quantify the initial target amplicon concentration, making it well-suited for food and water quality assessment. The developed PCR system performed DNA amplification at a level and speed comparable to larger and more expensive commercial table-top systems. The fluorescence detection sensitivity was also tested to be at the same level as commercially available multi-mode optical readers, thus making the PCR system an attractive solution for medical point-of-care and food and water quality assessment. Full article
(This article belongs to the Special Issue Point-of-Care Sensing Systems for Health Monitoring)
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