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Electrochemical Sensors for Food, Pharmaceutical and Biomedical Analysis
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Electrochemical Sensors for Food, Pharmaceutical and Biomedical Analysis

A special issue of Sensors (ISSN 1424-8220). This special issue belongs to the section "Biomedical Sensors".

Deadline for manuscript submissions: 10 September 2024 | Viewed by 1057

Special Issue Editor

Prof. Dr. Raluca-Ioana Stefan-van Staden

E-Mail Website
Guest Editor
Head of Laboratory of Electrochemistry and PATLAB, National Institute of Research for Electrochemistry and Condensed Matter, Bucharest, 300569 Timișoara, Romania
Interests: electrochemical sensors; chemistry; graphene; biomarkers; gastrointestinal cancer
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

High sensitivity and selectivity, quick response time, cost-effectiveness, and ease of application in situ/online are some advantages of electrochemical sensors, which have experienced great advances in recent decades.

Food, pharmaceutical and biomedical analyses require highly sensitive and selective methods. Electrochemical sensors are a very good alternative to standard methods of analysis performed in clinical and pharmaceutical laboratories. This Special Issue will emphasize new electroanalytical methods based on electrochemical sensors for food, pharmaceutical and biomedical analysis.

Prof. Dr. Raluca-Ioana Stefan-van Staden
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Sensors is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • electrochemical sensors
  • food analysis
  • pharmaceutical analysis
  • biomedical analysis

Published Papers (1 paper)

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Research

15 pages, 4430 KiB  
Article
Simultaneous Assay of CA 72-4, CA 19-9, CEA and CA 125 in Biological Samples Using Needle Three-Dimensional Stochastic Microsensors
by Alexandru-Adrian Bratei, Raluca-Ioana Stefan-van Staden, Ruxandra-Maria Ilie-Mihai and Damaris-Cristina Gheorghe
Sensors 2023, 23(19), 8046; https://doi.org/10.3390/s23198046 - 23 Sep 2023
Viewed by 831
Abstract
Two-needle 3D stochastic microsensors based on boron- and nitrogen-decorated gra-phenes, modified with N-(2-mercapto-1H-benzo[d]imidazole-5-yl), were designed and used for the molecular recognition and quantification of CA 72-4, CA 19-9, CEA and CA 125 biomarkers in biological samples such as whole blood, urine, saliva and [...] Read more.
Two-needle 3D stochastic microsensors based on boron- and nitrogen-decorated gra-phenes, modified with N-(2-mercapto-1H-benzo[d]imidazole-5-yl), were designed and used for the molecular recognition and quantification of CA 72-4, CA 19-9, CEA and CA 125 biomarkers in biological samples such as whole blood, urine, saliva and tumoral tissue. The NBGr-2 sensor yielded lower limits of determination. For CEA, the LOD was 4.10 × 10−15 s−1 g−1 mL, while for CA72-4, the LOD was 4.00 × 10−11 s−1 U−1 mL. When the NBGr-1 sensor was employed, the best results were obtained for CA12-5 and CA19-9, with values of LODs of 8.37 × 10−14 s−1 U−1 mL and 2.09 × 10−13 s−1 U−1 mL, respectively. High sensitivities were obtained when both sensors were employed. Broad linear concentration ranges favored their determination from very low to higher concentrations in biological samples, ranging from 8.37 × 10−14 to 8.37 × 103 s−1 U−1 mL for CA12-5 when using the NBGr-1 sensor, and from 4.10 × 10−15 to 2.00 × 10−7 s−1 g−1 mL for CEA when using the NBGr-2 sensor. Student’s t-test showed that there was no significant difference between the results obtained utilizing the two microsensors for the screening tests, at a 99% confidence level, with the results obtained being lower than the tabulated values. Full article
(This article belongs to the Special Issue Electrochemical Sensors for Food, Pharmaceutical and Biomedical Analysis)
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