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Advanced Nanozymes and Sensing Technologies for Biochemical Analysis

A special issue of Sensors (ISSN 1424-8220). This special issue belongs to the section "Nanosensors".

Deadline for manuscript submissions: 31 May 2024 | Viewed by 2452

Special Issue Editors

Nanozyme Medical Center, School of Basic Medical Sciences, Zhengzhou University, Zhengzhou 450001, China
Interests: nanozymes; disease diagnosis; tumor theranostics

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Guest Editor
School of Public Health, Hengyang Medical School, University of South China, Hengyang 421001, China
Interests: nanozymes; environmental detection; food analysis; biochemical sensing
Special Issues, Collections and Topics in MDPI journals
Institute of Biophysics, Chinese Academy of Sciences, Beijing, China
Interests: nanozymes; disease diagnosis; atherosclerosis

Special Issue Information

Dear Colleagues,

Enzyme-based biosensors have attracted the attention of the scientific community for their distinct advantages, such as increased sensitivity and specificity, as well as their faster response time when compared to most traditional analytical methods. However, they also face inevitable problems, such as relatively high cost and lack of stability, which severely limit their practical applicability. Recently, a class of nanomaterials with intrinsic enzyme-like properties, nanozymes, have emerged with significant benefits over their natural counterpart and have been exploited as a viable enzyme alternative for biosensing. In recent years, many nanozymes and nanozyme-based sensing technologies have been developed for biosensing. In this Special Issue, we solicit reviews, original research papers, and short communications covering the topic of Advanced Nanozymes and Sensing Technologies for Biochemical Analysis. Papers focused on the development of novel nanozymes or nanozyme-based sensing technologies for biochemical analysis are welcomed. 

Dr. Bing Jiang
Dr. Xiangheng Niu
Dr. Jiuyang He
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Sensors is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • nanozymes
  • biochemical sensing
  • immunoassay
  • disease diagnosis
  • nanozyme-based aptasensor
  • multi-enzyme biosensor
  • food analysis
  • environmental detection

Published Papers (1 paper)

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Research

15 pages, 6610 KiB  
Article
An In Situ Study on Nanozyme Performance to Optimize Nanozyme-Strip for Aβ Detection
by Yaying Luo, Haiming Luo, Sijia Zou, Jing Jiang, Demin Duan, Lei Chen and Lizeng Gao
Sensors 2023, 23(7), 3414; https://doi.org/10.3390/s23073414 - 24 Mar 2023
Cited by 1 | Viewed by 1474
Abstract
The nanozyme-strip is a novel POCT technology which is different from the conventional colloidal gold strip. It primarily utilizes the catalytic activity of nanozyme to achieve a high-sensitivity detection of target by amplifying the detection signal. However, previous research has chiefly focused on [...] Read more.
The nanozyme-strip is a novel POCT technology which is different from the conventional colloidal gold strip. It primarily utilizes the catalytic activity of nanozyme to achieve a high-sensitivity detection of target by amplifying the detection signal. However, previous research has chiefly focused on optimizing nanozyme-strip from the perspective of increasing nanozyme activity, little is known about other physicochemical factors. In this work, three sizes of Fe3O4 nanozyme and three sizes of CoFe2O4 nanozyme were used to investigate the key factors of nanozyme-strip for optimizing and improving its detection performance. We found that three sizes of Fe3O4 nanozyme all gather at the bottom of the nitrocellulose (NC) membrane, and three sizes of CoFe2O4 nanozyme migrate smoothly on the NC membrane, respectively. After color development, the surface of NC membranes distributed with CoFe2O4 peroxidase nanozymes had significant color change. Experimental results show that CoFe2O4 nanozymes had better dispersity than Fe3O4 nanozymes in an aqueous solution. We observed that CoFe2O4 nanozymes with smaller particle size migrated to the middle of the NC membrane with a higher number of particles. According to the results above, 55 ± 6 nm CoFe2O4 nanozyme was selected to prepare the nanozyme probe and achieved a highly sensitive detection of Aβ42Os on the nanozyme-strip. These results suggest that nanozyme should be comprehensively evaluated in its dispersity, the migration on NC membrane, and the peroxidase-like activity to determine whether it can be applied to nanozyme-strip. Full article
(This article belongs to the Special Issue Advanced Nanozymes and Sensing Technologies for Biochemical Analysis)
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