An Exploration of the Confluence between Pharmacogenomics and the Medication Experience

A special issue of Pharmacy (ISSN 2226-4787). This special issue belongs to the section "Pharmacy Practice and Practice-Based Research".

Deadline for manuscript submissions: 30 April 2024 | Viewed by 5467

Special Issue Editors

Essentia Institute of Rural Health, Duluth, MN 55812, USA
Interests: person-centeredness; community pharmacy; medication experience; pharmacy services; implementation science; community-integrated care
Special Issues, Collections and Topics in MDPI journals
College of Pharmacy, University of Minnesota, Minneapolis, MN, USA
Interests: pediatric pharmacotherapy; pharmacogenetics; pharmacogenomics; pharmacokinetics

Special Issue Information

Dear Colleagues,

Both pharmacogenomics (PGx) and the medication experience (MedXp) seek to understand how persons respond to medications to inform therapeutic choices that are best suited to the individual. While PGx utilizes an individual’s genetic makeup to guide medication dose and selection, the MedXp accounts for the individual’s subjective experience of taking a medication in their daily life. Neither approach will achieve their common goal without consideration of the other, and thus the sooner they cross paths, the better.

This Special Issue, titled An Exploration of the Confluence between Pharmacogenomics and the Medication Experience, aims to highlight connectivity between these two fields and accelerate their joint incorporation in pharmacist practice.  We invite the submission of manuscripts on this topic to this Special Issue in Pharmacy, an open access, scholarly journal of pharmacy education and practice. Potential topics include, but are not limited to: (1) how PGx affects the meaning, utility, and lived experience of taking daily medications; (2) approaches, techniques, and strategies that connect PGx and MedXp within pharmacy curricula; (3) opportunities and challenges for implementing pharmacist practice that integrates PGx and MedXp; (4) synergistic factors of PGx and MedXp for mediating or enhancing medication adherence; (5) the role of PGx and MedXp in person-centered, pharmaceutical care; (6) ethical considerations and implications of using PGx with MedXp to inform guidelines for care, shared decision making for therapeutics, and policy; (7) the use of PGx and MedXp to promote health equity and eliminate health disparities across key factors such as race, ethnicity, gender, sexual orientation, age, disability, socioeconomic status, and geographic location; and (8) epistemological synergies and tensions between PGx and MedXp. We seek papers of all types, including [a] reviews, [b] research articles, [c] policy and practice briefs, [d] case and demonstration studies, [e] original research articles.

There are opportunities for a discounted article processing fee, the applications for which will be reviewed on a case-by-case basis. If more than 10 papers are published in the Special Issue, the publisher will print a book edition available in both digital format (for free) and paperback copies (ordered via Amazon) on the MDPI platform (http://books.mdpi.com).

Dr. Anthony W. Olson
Dr. Jacob T. Brown
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Pharmacy is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • medication experience
  • pharmacogenomics
  • person-centeredness
  • precision medicine
  • evidence-based practice
  • pharmaceutical care

Published Papers (3 papers)

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Review

14 pages, 994 KiB  
Review
The Intersection between Pharmacogenomics and Health Equity: A Case Example
Pharmacy 2023, 11(6), 186; https://doi.org/10.3390/pharmacy11060186 - 05 Dec 2023
Viewed by 1427
Abstract
Pharmacogenomics (PGx) and the study of precision medicine has substantial power to either uplift health equity efforts or further widen the gap of our already existing health disparities. In either occurrence, the medication experience plays an integral role within this intersection on an [...] Read more.
Pharmacogenomics (PGx) and the study of precision medicine has substantial power to either uplift health equity efforts or further widen the gap of our already existing health disparities. In either occurrence, the medication experience plays an integral role within this intersection on an individual and population level. Examples of this intertwined web are highlighted through a case discussion. With these perspectives in mind, several recommendations for the research and clinical communities are highlighted to promote equitable healthcare with PGx integrated. Full article
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9 pages, 237 KiB  
Review
Intersection and Considerations for Patient-Centered Care, Patient Experience, and Medication Experience in Pharmacogenomics
Pharmacy 2023, 11(5), 146; https://doi.org/10.3390/pharmacy11050146 - 14 Sep 2023
Viewed by 1467
Abstract
As healthcare continues to embrace the concept of person- and patient-centered care, pharmacogenomics, patient experience, and medication experience will continue to play an increasingly important role in care delivery. This review highlights the intersection between these concepts and provides considerations for patient-centered medication [...] Read more.
As healthcare continues to embrace the concept of person- and patient-centered care, pharmacogenomics, patient experience, and medication experience will continue to play an increasingly important role in care delivery. This review highlights the intersection between these concepts and provides considerations for patient-centered medication and pharmacogenomic experiences. Elements at the patient, provider, and system level can be considered in the discussion, supporting the use of pharmacogenomics, with components of the patient and medication experience contributing to the mitigation of barriers surrounding patient use and the valuation of pharmacogenomic testing. Full article
11 pages, 567 KiB  
Review
Personalizing Personalized Medicine: The Confluence of Pharmacogenomics, a Person’s Medication Experience and Ethics
Pharmacy 2023, 11(3), 101; https://doi.org/10.3390/pharmacy11030101 - 15 Jun 2023
Cited by 2 | Viewed by 1605
Abstract
Truly personalized precision medicine combines pharmacogenomics (PGx), a person’s lived medication experiences and ethics; person-centeredness lies at the confluence of these considerations. A person-centered perspective can help inform PGx-related treatment guidelines, shared decision-making for PGx-related therapeutics and PGx-related healthcare policy. This article examines [...] Read more.
Truly personalized precision medicine combines pharmacogenomics (PGx), a person’s lived medication experiences and ethics; person-centeredness lies at the confluence of these considerations. A person-centered perspective can help inform PGx-related treatment guidelines, shared decision-making for PGx-related therapeutics and PGx-related healthcare policy. This article examines the interplay between these components of person-centered PGx-related care. Ethics concepts addressed include privacy, confidentiality, autonomy, informed consent, fiduciary responsibility, respect, the burden of pharmacogenomics knowledge for both the patient and healthcare provider and the pharmacist’s ethical role in PGx-testing. Incorporating the patient’s lived medication experience and ethics principles into PGx-based discussions of treatment can optimize the ethical, person-centered application of PGx testing to patient care. Full article
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