Advances in the Preparation and Technology of Pharmaceutical Solid Dosage Forms
A special issue of Pharmaceutics (ISSN 1999-4923). This special issue belongs to the section "Pharmaceutical Technology, Manufacturing and Devices".
Deadline for manuscript submissions: 31 August 2024 | Viewed by 161
Special Issue Editors
Interests: crystalline and amorphous pharmaceutical solid forms; poly(a)morphs; ball milling; solid-state characterization; crystal structure determination; X-ray diffraction; total scattering; molecular dynamics simulations
Special Issues, Collections and Topics in MDPI journals
Interests: solid-state pharmaceutical chemistry and materials science; crystallization processes; polymorphs; co-crystals; amorphous solids; solid-state characterization
Special Issue Information
Dear Colleagues,
One of the most pressing issues in drug development is to find strategies with which to improve the aqueous solubility and thereby the oral bioavailability of poorly water-soluble drugs. Several strategies, including the preparation of both crystalline and amorphous multicomponent solid forms (i.e., the combination of a drug with a second biologically acceptable molecule), have been considered as promising routes with which to overcome the poor water solubility problem of drugs. For instance, the combination of amorphous drugs with polymers (amorphous solid dispersions—ASDs) and small molecules (co-amorphous systems) has received considerable attention, not only for offering the possibility to improve drug solubility (therefore decreasing the drug dosage) but also for allowing the design of more stable drugs in an amorphous state.
Despite all of these promising strategies to improve the aqueous solubility of poorly water-soluble drugs, only a few multicomponent solid forms (e.g., co-crystals, co-amorphous, and ASDs) have been developed into marketed products, mainly because of inadequate physical stability during storage and challenges during the scale-up of manufacturing processes.
This Special Issue aims to share the latest advances in the preparation and technological development of solid pharmaceutical dosage forms. To this end, we invite the submission of papers covering broad topics in pharmaceutics. Topics may range from the preparation and characterization of new solid forms to the development of new methods and technological strategies to improve the physical stability and manufacturing processes of more soluble solid dosage forms.
Dr. Inês C. B. Martins
Dr. Daniele Musumeci
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Pharmaceutics is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- pharmaceutics
- solid dosage forms
- amorphous systems
- crystalline systems
- drug delivery systems
- solid-state characterization
- pharmaceutical technology
- manufacturing processes
