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► Journal BrowserSpecial Issue "Promising Small Molecule Compounds in Cancer Treatment"
A special issue of Pharmaceutics (ISSN 1999-4923). This special issue belongs to the section "Drug Targeting and Design".
Deadline for manuscript submissions: 31 August 2023 | Viewed by 81
Special Issue Editors
Interests: medicinal chemistry; natural products; triterpenes; organic synthesis; anticancer agents
Interests: medicinal chemistry; natural products; triterpenes; organic synthesis; anticancer agents
Special Issue Information
Dear Colleagues,
We are pleased to invite you to submit original scientific articles, review papers, or communications for a Special Issue of Pharmaceutics devoted to researching new small-molecule substances with anticancer activity.
The basis of cancer chemotherapy involves small-molecule cytostatics. These compounds are characterized by their ability to freely penetrate the lipid bilayer, and their solubility in water allows them to move around the body. Currently used cytostatics do not work selectively and also cause damage to normal cells. Their low selectivity and narrow therapeutic index determine high toxicity and lead to numerous side effects. Actions are constantly needed to improve the therapeutic index of the cytostatics used, inter alia, by interfering with the chemical structure of drugs. Research is also being conducted for new and developing derivatives with better pharmacokinetic properties and preparations, including the slow release of active substances.
This Special Issue aims to present the latest reports on natural and synthetic small-molecule compounds with anticancer activity, their preparation, the determination of the pharmacokinetic profile, and in vitro and in vivo studies.
Dr. Elwira Chrobak
Dr. Ewa Bębenek
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Pharmaceutics is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- anticancer agents
- natural products
- synthesis
- structure modification
- structure–activity relationship
- substance action on target
- biological evaluation
- cancer therapy
