Special Issue "Transport and Metabolism of Small-Molecule Drugs (Volume II)"

A special issue of Pharmaceutics (ISSN 1999-4923). This special issue belongs to the section "Pharmacokinetics and Pharmacodynamics".

Deadline for manuscript submissions: 30 November 2023 | Viewed by 77

Special Issue Editor

Department of Pharmaceutical Sciences, College of Pharmacy, University of Michigan, 428 Church Street, Ann Arbor, MI 48109, USA
Interests: drug transport; cellular pharmacokinetics; computational modeling; systems biology; cheminformatics; microscopic imaging
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Special Issue Information

Dear Colleagues,

This Special Issue will highlight studies centered on elucidating the biological processes and pathways that determine the absorption, distribution, metabolism, and excretion of drug-like chemical agents in the living organism. More specifically, we are seeking submissions related to studies of chemical agents with a molecular mass of <500 Daltons. Of special interest, we are seeking original research articles or reviews that present intellectually exciting and innovative ideas, including systems modeling and simulation approaches, or that offer unexpected insights into the pharmacokinetics of small drug-like molecules. We will also consider more traditional molecular-level studies looking at the interaction of small molecules with transporters, enzymes, membranes, and other macromolecular components that determine the distribution and disposition of chemical agents in cells, tissues, and organs. Hypothesis-driven and mechanistic studies related to regulatory science, such as the measurement and prediction of drug–drug interactions, the establishment of  in vitro–in vivo correlations, pharmacogenomics, interpatient variability, preclinical model systems (transgenic/knockout mice, isolated perfused organs, in vitro or in silico screening tools), or advanced computational approaches for modeling, simulating, or predicting pharmacokinetics at a multiscale level (from organelles to populations) are also welcome.

Prof. Dr. Gus Rosania
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Pharmaceutics is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • small molecules
  • pharmacokinetics
  • metabolism
  • drug–drug interactions
  • pharmacogenomics
  • drug targeting
  • drug delivery
  • in vitro–in vivo correlations
  • modeling and simulation

Related Special Issue

Published Papers

This special issue is now open for submission.
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