Prevalence, Molecular Characterization and Mechanism of Antiparasitic Resistance

Dear Colleagues,

Parasitic diseases, which occur worldwide, pose a threat to both human and animal health and remain a clinical, diagnostic and therapeutic challenge across the world. Among the six tropical diseases with a priority for containment defined by WNEP/World Bank/WHO/TDR, five are parasitic diseases. Although chronic non-communicable diseases are currently the major burden of disease, emerging and re-emerging parasitic diseases pose significant health, economic and social burdens in this wormy world, and the elimination of parasitic diseases as public health problems is included in the United Nations (UN) Sustainable Development Goals (SDGs). Notably, malaria, the most important parasitic disease in terms of its medical and socioeconomic significance, is estimated to affect 249 million people and cause 608 000 deaths globally, killing a child every minute.

Currently, chemical treatment remains the predominant strategy for the management of parasitic diseases; however, increasing evidence shows the emergence of drug-resistant parasite isolates following the long-term, extensive use of antiparasitic agents. Drug resistance poses a great threat to the ambitious goal of a parasite-free world. Unraveling the underlying mechanisms is a premise to responding to drug resistance in parasites and developing novel agents as alternatives.

To improve the understanding of drug resistance in parasites and facilitate the management of emergence of drug-resistant parasites, a Special Issue entitled “Prevalence, Molecular Characterization and Mechanism of Antiparasitic Resistance” is now open in Pathogens and Tropical Medicine and Infectious Disease. All submissions which fall into the scope of these two journals will be given full consideration for publication.

In this Special Issue, we call for papers communicating the latest knowledge on the prevalence, molecular characterization and mechanism of antiparasitic resistance and insecticide resistance. Original research and review articles pertaining to drug resistance in parasites are welcome, and interdisciplinary studies aiming at providing novel tools for the prediction, prevention and control of drug-resistant parasites are preferred. This topic aims to bring together policy makers, research scientists, clinical physicians, pharmacists, public health professionals and veterinarians who are working in diverse disciplines of parasitic diseases and pharmacology, thereby facilitating the management of drug resistance in parasites and insecticide resistance in vectors.

You may choose our Joint Special Issue in Tropical Medicine and Infectious Disease.

Dr. Jianhai Yin
Prof. Dr. Jian Li
Dr. Wei Wang
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Pathogens is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

• antiparasitic action
• drug resistance
• vector resistance
• insecticide resistance
• molecular characterization