Advances in Surface and Secreted Proteins in Gram-Positive Pathogens

A special issue of Pathogens (ISSN 2076-0817). This special issue belongs to the section "Bacterial Pathogens".

Deadline for manuscript submissions: 15 July 2024 | Viewed by 161

Special Issue Editors

Center for Infectious and Inflammatory Diseases, 2121 W. Holcombe Blvd., Houston, TX 77030, USA
Interests: bacteria and cancer; host-pathogen interactions; immune evasion
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Guest Editor
Center for Infectious and Inflammatory Diseases, 2121 W. Holcombe Blvd., Houston, TX 77030, USA
Interests: bacteria; host-pathogen interactions

Special Issue Information

Dear Colleagues,

Gram-positive pathogens pose a significant threat to public health. Gaining insight into the complex mechanisms through which these pathogens engage with hosts is crucial to the development of effective therapeutic strategies and the success of efforts to combat the rise of antibiotic resistance.

Surface and secreted proteins play a crucial role in the pathogenesis of Gram-positive pathogens, actively engaging with the host environment to promote bacterial survival, dissemination, and virulence.  Moreover, these factors hold great promise as vaccine candidates and prospective targets for clinical intervention.

This call-for-manuscripts aims to highlight recent advances in the study of surface and secreted proteins of Gram-positive pathogens, emphasizing their role in pathogenesis and virulence. We encourage submissions that explore various aspects of this topic, including but not limited to:

  1. Surface and secreted proteins that contribute to pathogen colonization, dissemination, transmission, and virulence.
  2. Molecular mechanisms underlying the interaction between surface/secreted proteins and their host targets.
  3. The impact of surface and secreted proteins on host responses and their mechanism of action, including the modulation of immune and non-immune cell behavior, tissue homeostasis, the complement system, coagulation, and hemostasis.
  4. Investigations into the impact of genetic heterogeneity at the inter- and intra-species level on the surface and secreted proteins on the virulence potential of gram-positive pathogens.

We welcome both experimental and computational studies, as well as review and perspective articles, that provide valuable insights into the most recent advances in this important topic area.

Dr. Yi Xu
Dr. Srishtee Arora
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Pathogens is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • microbiology
  • immune response
  • epidemiology
  • gram-positive pathogen
  • secretion
  • surface protein
  • pathogenesis
  • virulence
  • pathogen-host interaction

Published Papers

This special issue is now open for submission.
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