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Nanomaterials
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Nanomaterials with Functional Polymer Elements
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Nanomaterials with Functional Polymer Elements

A special issue of Nanomaterials (ISSN 2079-4991).

Deadline for manuscript submissions: closed (31 May 2018) | Viewed by 22598

Special Issue Editors

Dr. Nghia P. Truong

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Guest Editor
1. Faculty of Pharmacy and Pharmaceutical Sciences, Monash University, Parkville, VIC 3052, Australia
2. Department of Materials, ETH Zürich, HCI F531, Vladimir-Prelog-Weg 5, 8093 Zürich, Switzerland
Interests: polymer chemistry; nanomedicine; drug delivery; antimicrobial materials
Special Issues, Collections and Topics in MDPI journals
Dr. Mikey Whittaker

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Guest Editor
ARC Centre of Excellence in Convergent Bio-Nano Science and Technology, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, VIC 3052, Australia
Interests: functional soft matter; biomimetic materials; nanomedicines and manipulating the bio-nano interface
Dr. John Quinn

E-Mail Website
Guest Editor
ARC Centre of Excellence in Convergent Bio-Nano Science and Technology, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, VIC 3052, Australia
Interests: polymer synthesis; self-assembly and surface modification

Special Issue Information

Dear Colleagues,

The application of advanced polymer synthesis techniques have enabled the preparation of a wide array of functional nanomaterials. These techniques have yielded a broad suite of polymeric nanomaterials that have found applications in a variety of industries and research fields. In addition, the combination of functional polymers (e.g., stimuli-responsive, anti-fouling, biocompatible, antimicrobial, etc.) with nanostructured materials (e.g., iron oxide nanoparticles, graphene, carbon nanotubes, etc.) leads to novel hybrid nanomaterials with desirable physicochemical properties. In this Special Issue of Nanomaterials, we will highlight cutting-edge research on the topic of “Nanomaterials with Functional Polymer Elements”. In particular, this Special Issue will feature new developments in the synthesis, characterization and application of all polymeric nanomaterials and polymer-functionalized nanoparticles provided functional polymers are the key elements. We look forward to receiving your contribution to this exciting Special Issue of Nanomaterials.

Dr. Nghia Truong Phuoc
Dr. Mikey Whittaker
Dr. John Quinn
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Nanomaterials is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • Polymeric nanomaterials

  • Polymeric nanoparticles

  • Hybrid nanomaterials

  • Synthesis, characterization, property and application

  • Nanotoxicology

  • Nano-bio interactions

Published Papers (4 papers)

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Research

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20 pages, 5191 KiB  
Article
Preparation and Characterization of WS2@SiO2 and WS2@PANI Core-Shell Nanocomposites
by Hagit Sade and Jean-Paul Lellouche
Nanomaterials 2018, 8(3), 156; https://doi.org/10.3390/nano8030156 - 10 Mar 2018
Cited by 15 | Viewed by 6190
Abstract
Two tungsten disulfide (WS2)-based core-shell nanocomposites were fabricated using readily available reagents and simple procedures. The surface was pre-treated with a surfactant couple in a layer-by-layer approach, enabling good dispersion of the WS2 nanostructures in aqueous media and providing a [...] Read more.
Two tungsten disulfide (WS2)-based core-shell nanocomposites were fabricated using readily available reagents and simple procedures. The surface was pre-treated with a surfactant couple in a layer-by-layer approach, enabling good dispersion of the WS2 nanostructures in aqueous media and providing a template for the polymerization of a silica (SiO2) shell. After a Stöber-like reaction, a conformal silica coating was achieved. Inspired by the resulting nanocomposite, a second one was prepared by reacting the surfactant-modified WS2 nanostructures with aniline and an oxidizing agent in an aqueous medium. Here too, a conformal coating of polyaniline (PANI) was obtained, giving a WS2@PANI nanocomposite. Both nanocomposites were analyzed by electron microscopy, energy dispersive X-ray spectroscopy (EDS) and FTIR, verifying the core-shell structure and the character of shells. The silica shell was amorphous and mesoporous and the surface area of the composite increases with shell thickness. Polyaniline shells slightly differ in their morphologies dependent on the acid used in the polymerization process and are amorphous like the silica shell. Electron paramagnetic resonance (EPR) spectroscopy of the WS2@PANI nanocomposite showed variation between bulk PANI and the PANI shell. These two nanocomposites have great potential to expand the use of transition metals dichalcogenides (TMDCs) for new applications in different fields. Full article
(This article belongs to the Special Issue Nanomaterials with Functional Polymer Elements)
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27 pages, 2862 KiB  
Article
Polymer-Based Nanocarriers for Co-Delivery and Combination of Diverse Therapies against Cancers
by Guowen Yan, Aihua Li, Aitang Zhang, Yong Sun and Jingquan Liu
Nanomaterials 2018, 8(2), 85; https://doi.org/10.3390/nano8020085 - 03 Feb 2018
Cited by 27 | Viewed by 6445
Abstract
Cancer gives rise to an enormous number of deaths worldwide nowadays. Therefore, it is in urgent need to develop new therapies, among which combined therapies including photothermal therapy (PTT) and chemotherapy (CHT) using polymer-based nanocarriers have attracted enormous interest due to the significantly [...] Read more.
Cancer gives rise to an enormous number of deaths worldwide nowadays. Therefore, it is in urgent need to develop new therapies, among which combined therapies including photothermal therapy (PTT) and chemotherapy (CHT) using polymer-based nanocarriers have attracted enormous interest due to the significantly enhanced efficacy and great progress has been made so far. The preparation of such nanocarriers is a comprehensive task involving the cooperation of nanomaterial science and biomedicine science. In this review, we try to introduce and analyze the structure, preparation and synergistic therapeutic effect of various polymer-based nanocarriers composed of anti-tumor drugs, nano-sized photothermal materials and other possible parts. Our effort may bring benefit to future exploration and potential applications of similar nanocarriers. Full article
(This article belongs to the Special Issue Nanomaterials with Functional Polymer Elements)
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1692 KiB  
Article
Evaluation of Different Single-Walled Carbon Nanotube Surface Coatings for Single-Particle Tracking Applications in Biological Environments
by Zhenghong Gao, Noémie Danné, Antoine Guillaume Godin, Brahim Lounis and Laurent Cognet
Nanomaterials 2017, 7(11), 393; https://doi.org/10.3390/nano7110393 - 16 Nov 2017
Cited by 19 | Viewed by 4061
Abstract
Fluorescence imaging of biological systems down to the single-molecule level has generated many advances in cellular biology. For applications within intact tissue, single-walled carbon nanotubes (SWCNTs) are emerging as distinctive single-molecule nanoprobes, due to their near-infrared photoluminescence properties. For this, SWCNT surfaces must [...] Read more.
Fluorescence imaging of biological systems down to the single-molecule level has generated many advances in cellular biology. For applications within intact tissue, single-walled carbon nanotubes (SWCNTs) are emerging as distinctive single-molecule nanoprobes, due to their near-infrared photoluminescence properties. For this, SWCNT surfaces must be coated using adequate molecular moieties. Yet, the choice of the suspension agent is critical since it influences both the chemical and emission properties of the SWCNTs within their environment. Here, we compare the most commonly used surface coatings for encapsulating photoluminescent SWCNTs in the context of bio-imaging applications. To be applied as single-molecule nanoprobes, encapsulated nanotubes should display low cytotoxicity, and minimal unspecific interactions with cells while still being highly luminescent so as to be imaged and tracked down to the single nanotube level for long periods of time. We tested the cell proliferation and cellular viability of each surface coating and evaluated the impact of the biocompatible surface coatings on nanotube photoluminescence brightness. Our study establishes that phospholipid-polyethylene glycol-coated carbon nanotube is the best current choice for single nanotube tracking experiments in live biological samples. Full article
(This article belongs to the Special Issue Nanomaterials with Functional Polymer Elements)
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Review

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11 pages, 16543 KiB  
Review
Current Conjugation Methods for Immunosensors
by Zeyang Li and Guan-Yu Chen
Nanomaterials 2018, 8(5), 278; https://doi.org/10.3390/nano8050278 - 26 Apr 2018
Cited by 53 | Viewed by 5415
Abstract
Recent advances in the development of immunosensors using polymeric nanomaterials and nanoparticles have enabled a wide range of new functions and applications in diagnostic and prognostic research. One fundamental challenge that all immunosensors must overcome is to provide the specificity of target molecular [...] Read more.
Recent advances in the development of immunosensors using polymeric nanomaterials and nanoparticles have enabled a wide range of new functions and applications in diagnostic and prognostic research. One fundamental challenge that all immunosensors must overcome is to provide the specificity of target molecular recognition by immobilizing antibodies, antibody fragments, and/or other peptides or oligonucleotide molecules that are capable of antigen recognition on a compact device surface. This review presents progress in the application of immobilization strategies including the classical adsorption process, affinity attachment, random cross-linking and specific covalent linking. The choice of immobilization methods and its impact on biosensor performance in terms of capture molecule loading, orientation, stability and capture efficiency are also discussed in this review. Full article
(This article belongs to the Special Issue Nanomaterials with Functional Polymer Elements)
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