Special Issue "Metal-Based Nanomaterials for Biomedical, Agricultural, and Environmental Applications: Prospects and Uncertainties"
Deadline for manuscript submissions: 15 December 2023 | Viewed by 18246
Interests: nanotoxicology; plant nanobiotechnology; antibacterial nanomaterials; carbon nanomaterials; bioaccumulation of nanoparticles
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Recently, metal-based nanomaterials such as metal nanoparticles, metal oxides, and hybrid nanomaterials, have found wide application in various fields.In biomedicine, these nanomaterials are used to develop promising biosensors, drug and gene delivery instruments, theranostic agents, antibacterial and anticancer drugs, and tissue engineering constructs.
In agriculture and the food industry, metal-based nanomaterials are used to develop smart fertilizers, growth regulators, pesticides, soil improvers, biosensors, and packaging materials.
In environmental protection, metal-based nanomaterials are being considered for the removal of contaminants from air, water, and soil, soil remediation, catalytic conversion of carbon dioxide, and green energy applications.
At the same time, the sustainable use of metal-based nanomaterials is not possible without a comprehensive assessment of their safety for the environment, including transfer in food chains, as well as for human health.
Papers dedicated to all of these topics are welcome in the Special Issue. In addition, works presenting new methods and research results for nano-bio interfaces are also welcome.
Dr. Alexander Gusev
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Nanomaterials is an international peer-reviewed open access semimonthly journal published by MDPI.
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- metal-based nanomaterials
- nano-bio interface
The below list represents only planned manuscripts. Some of these manuscripts have not been received by the Editorial Office yet. Papers submitted to MDPI journals are subject to peer-review.
Title: Molecularly Targeted Lanthanide Nanoparticles for Cancer Theranostic Applications
Authors: Guillermina Ferro-Flores; Alejandra Ancira-Cortez; Blanca Ocampo- García; Laura Meléndez-Alafort
Affiliation: 1 Department of Radioactive Materials, Instituto Nacional de Investigaciones Nucleares, Ocoyoacac 52750, Mexico 2 Immunology and Molecular Oncology Unit, Veneto Institute of Oncology IOV-IRCCS, Via Gattamelata 64, 35138 Padova, Italy * Correspondence: firstname.lastname@example.org
Abstract: Abstract Injectable colloidal solutions of lanthanide oxides (nanoparticles between 10 and 100 nm in size) have demonstrated high biocompatibility and no toxicity when the nanoparticulate units are functionalized with specific biomolecules that molecularly target various proteins in the tumor microenvironment. Among the proteins successfully targeted by functionalized lanthanide nanoparticles are fibroblast activation protein (FAP), programmed death ligand (PD-L1), gastrin-releasing peptide receptor (GRP-R), prostate-specific membrane antigen (PSMA), and integrins associated with tumor neovasculature. Lutetium, samarium, europium, holmium, and terbium, either as lanthanide oxide nanoparticles or as nanoparticles doped with lanthanide ions, have demonstrated their theranostic potential through their ability to generate molecular images by magnetic resonance, nuclear, optical, or computed tomography imaging. Likewise, photodynamic therapy, targeted radiotherapy (neutron-activated nanoparticles), and image-guided tumor therapy are some examples of their potential therapeutic applications. This review provides an overview of cancer theranostics based on lanthanide nanoparticles coated with specific peptides targeting the tumor microenvironment.