Carbon-Based Nanocomposites and Printing Technologies for Sensing Approaches

A special issue of Nanomaterials (ISSN 2079-4991). This special issue belongs to the section "2D and Carbon Nanomaterials".

Deadline for manuscript submissions: 20 May 2024 | Viewed by 1031

Special Issue Editor


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Guest Editor
GENOCOV Research Group, Departament of Chemistry, Faculty of Science, Edifici C-Nord, Universitat Autònoma de Barcelona, Carrer del Til·lers, 08193 Bellaterra, Spain
Interests: microsystems for chemical analysis based on 3D- and inkjet-printed technologies; the electrochemical improvement of voltammetry (bio)sensors based on carbon graphite forms; the customization of carbon nanomaterials with several bio-modifiers, including metal nanoparticles, quantum dots and macro-molecules; the development of automated analyzers for bioreactor control and bioelectrochemistry cells
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Special Issue Information

Dear Colleagues,

Recent advances in nanoscience and nanotechnology have brought about nanometer-scale novel devices and materials due to the demand for miniaturized electronic, optical, sensing, and actuating systems and components. Carbon nanomaterials are a key component of nanotechnology. Nanocomposite carbon-paste electrodes (NC-CPEs) made of various dispersing, conducting carbon nanostructures in an insulating polymer have played a leading role in analytical electrochemistry.  Carbon nanohorns, carbon nanotubes, carbon nanofibers, graphene, graphite and related materials are examples of carbon nanoallotropes that can be successfully modified to improve selectivity (nanoparticles, enzymes, antibodies, aptamers or chemical (bio)recognition agents). Thus, they can be integrated as the core of (bio)sensing platforms due to their excellent ability to directly interact with a wide range of analytes, their applicability in aqueous media and their superb electrical conductivity, among other properties. For this reason, many researchers have worked toward the development of novel carbon-based nanocomposite (bio)sensing platforms based on printing technologies.

Printing technologies have created a whole new range of possibilities for the fabrication of (bio)sensing platforms. Inkjet printing technology, for example, can rapidly produce low-cost, highly reproducible, miniaturized electrodes, mainly due to the lack of need for masks, meaning that sensing applications can be designed and tested at a much higher rate. Highly versatile and accessible 3D printing represents another promising technology.  With a wide range of polymeric materials with solvent-resistant, electric conductive, elastic or transparent properties, they play host to newly designed analytical platforms that can integrate all stages of the analytical procedure, from sample pre-treatment to coupling a detector.

This Special Issue of Nanomaterials aims to cover the current trends in the use of carbon-based nanocomposite electronic devices and printing technologies for (bio)sensing approaches, including all nanoallotropic carbon forms and their tuning and (bio)functionalization with nanoparticles, biological elements, active biomolecules or magnetic beads, both inkjet- and 3D-printed.

Dr. Mireia Baeza
Guest Editor

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Keywords

  • carbon nanomaterials
  • functional metal nanoparticles
  • biorecognition agents
  • supramolecular active biomolecules
  • magento nanocomposites
  • carbon-paste electrodes
  • electrochemical detection
  • electronic analysis
  • biosensors
  • inkjet-printed
  • 3D-printed
  • microfluidic systems

Published Papers (1 paper)

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Research

12 pages, 1961 KiB  
Article
Amperometric Inkjet-Printed Thyroxine Sensor Based on Customized Graphene and Tunned Cyclodextrins as the Preconcentration Element
by María Jesús Ortiz-Aguayo, Franc Paré, Gemma Gabriel and Mireia Baeza
Nanomaterials 2024, 14(5), 403; https://doi.org/10.3390/nano14050403 - 22 Feb 2024
Viewed by 655
Abstract
The determination of thyroid hormones has practical clinical significance for the diagnosis of hyperthyroidism and hypothyroidism diseases. Considering this aspect, a wide range of analytical methods for the detection of analytes, including immunoassay, chemiluminescence, mass spectroscopy and high-performance liquid chromatography, among others, has [...] Read more.
The determination of thyroid hormones has practical clinical significance for the diagnosis of hyperthyroidism and hypothyroidism diseases. Considering this aspect, a wide range of analytical methods for the detection of analytes, including immunoassay, chemiluminescence, mass spectroscopy and high-performance liquid chromatography, among others, has been developed. This type of analysis provides feasible results. Nevertheless, it requires qualified staff, special facilities and is time-consuming. For this reason, this paper relies on the fabrication of an electrochemical device developed with inkjet printing technology for the free detection of Thyroxine (T4). To manufacture our electrochemical device, several aspects were considered from the use of materials that amplify electrical signals, to finding a supramolecular scaffold that possess affinity towards the target analyte and the need of preconcentrating the analyte on the electrode’s surface. For this task, printed devices were modified with a hybrid nanomaterial consisting of reduced graphene oxide (rGO) tuned with Au nanoparticles (Au–NPs) and an entrapment agent and different thiolated cyclodextrins (x–CD-SH) as carrying agents. Analytes were preconcentrated via supramolecular chemistry due to the formation of an inclusion complex between the cyclodextrin and hormones. Morphological and electrochemical characterization of the final device was carried out to ensure the proper workability of the electrode, achieving excellent response, sensitivity and limit of detection (LOD). Full article
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