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Nanomaterials
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Synthesis and Applications of Gold Nanoparticles: 2nd Edition
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Synthesis and Applications of Gold Nanoparticles: 2nd Edition

A special issue of Nanomaterials (ISSN 2079-4991). This special issue belongs to the section "Synthesis, Interfaces and Nanostructures".

Deadline for manuscript submissions: 31 May 2024 | Viewed by 1218

Special Issue Editor

Prof. Dr. Wen-Huei Chang

E-Mail Website
Guest Editor
Department of Applied Chemistry, National Pingtung University, Pingtung, Taiwan
Interests: plasmonic biosensing; gold nanoparticles photoreduction; photoresist
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

The pervasive utilization of gold nanoparticles (AuNPs) has stemmed from their distinctive optical, electronic, and physical attributes. AuNP applications continue to evolve, encompassing electronics, sensors, diagnostics, solar cells, catalysis, nanoengineering, photodynamic therapy, therapeutic agent delivery, and more.

In this Special Issue, we eagerly anticipate exceptional contributions centered around the theme of "Synthesis and Applications of Gold Nanoparticles". Encompassing both fundamental principles and the latest advancements, this collection aims to spotlight the highly promising field of gold nanoparticles, with the aim to engage the widest possible audience. Embracing subjects such as AuNP synthesis, their integration with biologically compatible ligands, diagnostics, plasmon-based labeling and imaging, optical and electrochemical sensing, as well as disease-specific therapies, we invite dedicated researchers to submit original research papers or comprehensive review articles, allowing us to collectively present the forefront of progress in this dynamic field.

We look forward to receiving your contributions.

Prof. Dr. Wen-Huei Chang
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Nanomaterials is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • gold nanoparticles
  • metal nanoparticles
  • photonics
  • green synthesis
  • nanotechnology
  • functional material
  • biomedical applications

Published Papers (1 paper)

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Research

16 pages, 3806 KiB  
Article
Shape-Driven Response of Gold Nanoparticles to X-rays
by Simona Tarantino, Caterina Capomolla, Alessandra Carlà, Livia Giotta, Mariafrancesca Cascione, Chiara Ingrosso, Edoardo Scarpa, Loris Rizzello, Anna Paola Caricato, Rosaria Rinaldi and Valeria De Matteis
Nanomaterials 2023, 13(19), 2719; https://doi.org/10.3390/nano13192719 - 07 Oct 2023
Viewed by 1044
Abstract
Radiotherapy (RT) involves delivering X-ray beams to the tumor site to trigger DNA damage. In this approach, it is fundamental to preserve healthy cells and to confine the X-ray beam only to the malignant cells. The integration of gold nanoparticles (AuNPs) in the [...] Read more.
Radiotherapy (RT) involves delivering X-ray beams to the tumor site to trigger DNA damage. In this approach, it is fundamental to preserve healthy cells and to confine the X-ray beam only to the malignant cells. The integration of gold nanoparticles (AuNPs) in the X-ray methodology could be considered a powerful tool to improve the efficacy of RT. Indeed, AuNPs have proven to be excellent allies in contrasting tumor pathology upon RT due to their high photoelectric absorption coefficient and unique physiochemical properties. However, an analysis of their physical and morphological reaction to X-ray exposure is necessary to fully understand the AuNPs’ behavior upon irradiation before treating the cells, since there are currently no studies on the evaluation of potential NP morphological changes upon specific irradiations. In this work, we synthesized two differently shaped AuNPs adopting two different techniques to achieve either spherical or star-shaped AuNPs. The spherical AuNPs were obtained with the Turkevich–Frens method, while the star-shaped AuNPs (AuNSs) involved a seed-mediated approach. We then characterized all AuNPs with Transmission Electron Microscopy (TEM), Uv-Vis spectroscopy, Dynamic Light Scattering (DLS), zeta potential and Fourier Transform Infrared (FTIR) spectroscopy. The next step involved the treatment of AuNPs with two different doses of X-radiation commonly used in RT, namely 1.8 Gy and 2 Gy, respectively. Following the X-rays’ exposure, the AuNPs were further characterized to investigate their possible physicochemical and morphological alterations induced with the X-rays. We found that AuNPs do not undergo any alteration, concluding that they can be safely used in RT treatments. Lastly, the actin rearrangements of THP-1 monocytes treated with AuNPs were also assessed in terms of coherency. This is a key proof to evaluate the possible activation of an immune response, which still represents a big limitation for the clinical translation of NPs. Full article
(This article belongs to the Special Issue Synthesis and Applications of Gold Nanoparticles: 2nd Edition)
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