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Nanomaterials
Special Issues
Recent Advances in Metal Nanoparticles and Nanotoxicity
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Recent Advances in Metal Nanoparticles and Nanotoxicity

A special issue of Nanomaterials (ISSN 2079-4991). This special issue belongs to the section "Biology and Medicines".

Deadline for manuscript submissions: closed (31 May 2023) | Viewed by 1382

Special Issue Editors

Prof. Dr. Rosa Carotenuto

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Guest Editor
Department of Biology, University of Naples, Naples, Italy
Interests: use of the model organism Xenopus laevis for ecotoxicology and nanotoxicology studies
Prof. Dr. Bice Avallone

E-Mail Website
Guest Editor
Department of Biology, University of Naples, Naples, Italy
Interests: high specialization in optical microscopy and scanning and transmission electron microscopy applied to the characterization of pathological effects due to toxic substances, pollutants and genetic mutation

Special Issue Information

Dear Colleagues,

Metal nanoparticles (MNPs) represent a very important class of nanomaterials, and their study is one of the major research topics in nanoscience. They are qualitatively different from the corresponding macroscopic metallic materials; in fact, their electronic, optical and magnetic properties change dramatically as a result of small changes in size and atomic structure. Industrial progress has caused the increase of natural nanoparticles in an artificial and significant way. Indeed, these nanomaterials have numerous fields of application: from electronics to telecommunications and biology and most of them are considered non-toxic and bio-safe, so they are widely used as drug carriers, in medical materials, as antimicrobial materials or as remediation agents in contaminated soils and sediments. The technological challenge today is to be able to precisely control the size and shape of nanoparticles in order to control their properties of application interest. However, a major concern is their impact on human and environmental health. Therefore, it is essential to ask in what direction knowledge of nanomaterials and, in particular, those of a metallic nature is going, starting from production and development of their characteristics to their bioavailability, degradability, reactivity and toxicity. Therefore, it is necessary to evaluate their activity under in vivo conditions also. The purpose of this special issue is to cover all aspects of the latest advances in the production and application of metallic nanoparticles, also considering their effects on human and environmental health. Therefore, original research articles, communications or reviews are welcome.

All researchers in the field are cordially encouraged to submit their manuscripts for publication in this special issue.

Prof. Dr. Rosa Carotenuto
Prof. Dr. Bice Avallone
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Nanomaterials is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • MNPs production
  • MNPs biosafety
  • MNPs toxicity
  • MNPs control
  • health
  • environment

Published Papers (2 papers)

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Research

17 pages, 5321 KiB  
Article
Adverse Effect of Metallic Gold and Silver Nanoparticles on Xenopus laevis Embryogenesis
by Rosa Carotenuto, Margherita Tussellino, Sabato Fusco, Giovanna Benvenuto, Fabio Formiggini, Bice Avallone, Chiara Maria Motta, Chiara Fogliano and Paolo Antonio Netti
Nanomaterials 2023, 13(17), 2488; https://doi.org/10.3390/nano13172488 - 4 Sep 2023
Viewed by 1066
Abstract
Exposure to metal nanoparticles is potentially harmful, particularly when occurring during embryogenesis. In this study, we tested the effects of commercial AuNPs and AgNPs, widely used in many fields for their features, on the early development of Xenopus laevis, an anuran amphibian [...] Read more.
Exposure to metal nanoparticles is potentially harmful, particularly when occurring during embryogenesis. In this study, we tested the effects of commercial AuNPs and AgNPs, widely used in many fields for their features, on the early development of Xenopus laevis, an anuran amphibian key model species in toxicity testing. Through the Frog Embryo Teratogenesis Assay—Xenopus test (FETAX), we ascertained that both nanoparticles did not influence the survival rate but induced morphological anomalies like modifications of head and branchial arch cartilages, depigmentation of the dorsal area, damage to the intestinal brush border, and heart rate alteration. The expression of genes involved in the early pathways of embryo development was also modified. This study suggests that both types of nanoparticles are toxic though nonlethal, thus indicating that their use requires attention and further study to better clarify their activity in animals and, more importantly, in humans. Full article
(This article belongs to the Special Issue Recent Advances in Metal Nanoparticles and Nanotoxicity)
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17 pages, 15302 KiB  
Article
Milk Protein Adsorption on Metallic Iron Surfaces
by Parinaz Mosaddeghi Amini, Julia Subbotina and Vladimir Lobaskin
Nanomaterials 2023, 13(12), 1857; https://doi.org/10.3390/nano13121857 - 14 Jun 2023
Cited by 3 | Viewed by 1297
Abstract
Food processing and consumption involves multiple contacts between biological fluids and solid materials of processing devices, of which steel is one of the most common. Due to the complexity of these interactions, it is difficult to identify the main control factors in the [...] Read more.
Food processing and consumption involves multiple contacts between biological fluids and solid materials of processing devices, of which steel is one of the most common. Due to the complexity of these interactions, it is difficult to identify the main control factors in the formation of undesirable deposits on the device surfaces that may affect safety and efficiency of the processes. Mechanistic understanding of biomolecule–metal interactions involving food proteins could improve management of these pertinent industrial processes and consumer safety in the food industry and beyond. In this work, we perform a multiscale study of the formation of protein corona on iron surfaces and nanoparticles in contact with cow milk proteins. By calculating the binding energies of proteins with the substrate, we quantify the adsorption strength and rank proteins by the adsorption affinity. We use a multiscale method involving all-atom and coarse-grained simulations based on generated ab initio three-dimensional structures of milk proteins for this purpose. Finally, using the adsorption energy results, we predict the composition of protein corona on iron curved and flat surfaces via a competitive adsorption model. Full article
(This article belongs to the Special Issue Recent Advances in Metal Nanoparticles and Nanotoxicity)
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