Nanomaterials and Low-Dimensional Materials for Antibacterial Applications

A special issue of Nanomaterials (ISSN 2079-4991). This special issue belongs to the section "Biology and Medicines".

Deadline for manuscript submissions: closed (20 April 2024) | Viewed by 1408

Special Issue Editor

College of Chemical Engineering, Nanjing Forestry University, Nanjing, China
Interests: development and biological application of novel antimicrobial dressings; design and preparation of multiple smart-responsive hydrogels; preparation, modification and characterization of biomedical materials; preparation and characterization of bio-based polymers and composites; development and utilization of new anti-corrosion and anti-fouling coatings

Special Issue Information

Dear Colleagues,

The widespread use of antibiotics has led to the escalation of bacterial resistance, therefore, new and effective treatment options are required urgently. Advanced nanomaterials are particularly promising due to their drug loading/releasing capabilities and potential photodynamic/photothermal therapeutic properties. These nanomaterials are usually based on metals, metal oxides, or carbon materials. Crucially, dimension is an important asset of nanomaterials, which can change the intrinsic properties of materials. The dimensional differences in the materials lead to different antibacterial mechanisms. For example, 0-D (0-dimensional) nanomaterials can be used both as metal ion-releasing therapeutics and as carriers for antibiotic delivery. The 1-D (1-dimensional) rod-like nanomaterials are similar to 0-D in terms of properties and applications, while 1-D ribbon nanomaterials are more similar to 2-D (2-dimensional). The 2-D nanomaterials have been used to load therapeutic agents due to their large surface area. With sharp edges, they can also directly destroy bacteria by physical cutting. The 2-D materials are also degradable in the human body, thus they are very popular in antibacterial applications.

This Special Issue focuses on the latest studies and practical applications of 0-D, 1-D, and 2-D nanomaterials for antibacterial applications. It aims to publish original research papers and comprehensive reviews concerning the fabrication, characterization, advanced properties investigations, and potential applications of antibacterial nanomaterials.

We look forward to receiving your contributions.

Dr. Wei Shao
Guest Editor

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Keywords

  • nanomaterials
  • antibacterial
  • low-dimensional
  • metals
  • carbon materials

Published Papers (1 paper)

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Research

11 pages, 14363 KiB  
Article
Gentamicin Sulfate Grafted Magnetic GO Nanohybrids with Excellent Antibacterial Properties and Recyclability
by Xing Wu, Jingya Zhou, Zeng Liu and Wei Shao
Nanomaterials 2023, 13(8), 1416; https://doi.org/10.3390/nano13081416 - 20 Apr 2023
Viewed by 1096
Abstract
In this study, magnetic graphene oxide (MGO) nanohybrids were first prepared by loading Fe3O4 NPs onto graphene oxide (GO). Then, GS-MGO nanohybrids were prepared by grafting gentamicin sulfate (GS) onto MGO directly using a simple amidation reaction. The prepared GS-MGO [...] Read more.
In this study, magnetic graphene oxide (MGO) nanohybrids were first prepared by loading Fe3O4 NPs onto graphene oxide (GO). Then, GS-MGO nanohybrids were prepared by grafting gentamicin sulfate (GS) onto MGO directly using a simple amidation reaction. The prepared GS-MGO had the same magnetism as MGO. They exhibited excellent antibacterial ability against Gram-negative bacteria and Gram-positive bacteria. The GS-MGO had excellent antibacterial performance against Escherichia coli (E. coli), Staphylococcus aureus (S. aureus), and Listeria monocytogenes (L. monocytogenes). When the addition concentration of GS-MGO was 1.25 mg/mL, the calculated bacteriostatic ratios against E. coli and S. aureus achieved 89.8% and 100%, respectively. For L. monocytogenes, only 0.05 mg/mL of GS-MGO had an antibacterial ratio as high as 99%. In addition, the prepared GS-MGO nanohybrids also exhibited excellent non-leaching activity with good recycling antibacterial ability. After eight times antibacterial tests, GS-MGO nanohybrids still exhibited an excellent inhibition effect on E. coli, S. aureus, and L. monocytogenes. Therefore, as a non-leaching antibacterial agent, the fabricated GS-MGO nanohybrid had dramatic antibacterial properties and also showed great recycling ability. Thus, it displayed great potential in the design of novel recycling antibacterial agents with non-leaching activity. Full article
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