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Ultrasound and Microwave-Assisted Organic Synthesis

A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Ultrasound Chemistry".

Deadline for manuscript submissions: closed (30 June 2022) | Viewed by 2434

Special Issue Editor

Dipartimento di Scienza e Tecnologia del Farmaco, Università di Torino, Via P. Giuria 9, 10125 Torino, Italy
Interests: organic synthesis; surface modification; carbon based nanomaterials; cyclodextrins
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

High-value product synthesis can be reached by means of alternative energy sources, such as ultrasound irradiation. Synthesis of organic molecules and nanoparticles for use in organic synthesis, catalyst preparation are important domains in the fine chemical and pharmaceutical industries, and ultrasound irradiation provides a source of mechanical energy which can be used to improve reaction rate, yield, and selectivity in a wide range of chemical processes. This Special Issue of the journal is devoted to chemical reactions induced or promoted by ultrasonic waves, namely, sonochemistry to provide an alternative to other enabling technologies with the aim to access new synthetic pathways, new mechanisms, and catalyst and nanoparticle preparation. Sonochemistry covers a multidisciplinary approach integrating chemistry, physics, and process technology, and therefore, the Special Issue is also addressed to the reactor design and to the development of a hybrid reactor in which synergistic effects of ultrasound combined with other technologies are studied for intensified chemical syntheses in terms of energy and resource efficiency.

Prof. Dr. Katia Martina
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • ultrasound
  • sonochemistry
  • green synthetic processes
  • nanoparticles
  • innovation
  • hybrid technologies
  • process intensification

Published Papers (1 paper)

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18 pages, 3718 KiB  
Microwave-Assisted Synthesis of Modified Glycidyl Methacrylate–Ethyl Methacrylate Oligomers, Their Physico-Chemical and Biological Characteristics
Molecules 2022, 27(2), 337; - 06 Jan 2022
Cited by 1 | Viewed by 1906
In this study, well-known oligomers containing ethyl methacrylate (EMA) and glycidyl methacrylate (GMA) components for the synthesis of the oligomeric network [P(EMA)-co-(GMA)] were used. In order to change the hydrophobic character of the [P(EMA)-co-(GMA)] to a more hydrophilic one, [...] Read more.
In this study, well-known oligomers containing ethyl methacrylate (EMA) and glycidyl methacrylate (GMA) components for the synthesis of the oligomeric network [P(EMA)-co-(GMA)] were used. In order to change the hydrophobic character of the [P(EMA)-co-(GMA)] to a more hydrophilic one, the oligomeric chain was functionalized with ethanolamine, xylitol (Xyl), and L-ornithine. The oligomeric materials were characterized by nuclear magnetic resonance and Fourier transform infrared spectroscopy, scanning electron microscopy, and differential thermogravimetric analysis. In the final stage, thanks to the large amount of -OH groups, it was possible to obtain a three-dimensional hydrogel (HG) network. The HGs were used as a matrix for the immobilization of methylene blue, which was chosen as a model compound of active substances, the release of which from the matrix was examined using spectrophotometric detection. The cytotoxic test was performed using fluid extracts of the HGs and human skin fibroblasts. The cell culture experiment showed that only [P(EMA)-co-(GMA)] and [P(EMA)-co-(GMA)]-Xyl have the potential to be used in biomedical applications. The studies revealed that the obtained HGs were porous and non-cytotoxic, which gives them the opportunity to possess great potential for use as an oligomeric network for drug reservoirs in in vitro application. Full article
(This article belongs to the Special Issue Ultrasound and Microwave-Assisted Organic Synthesis)
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