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Nanometric Micelles: Synthesis, Characterization, and Application to Various Fields

A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Nanochemistry".

Deadline for manuscript submissions: closed (30 November 2020) | Viewed by 3672

Special Issue Editor

Service de Chimie Bioorganique et de Marquage (SCBM), CEA, Université Paris-Saclay, 91191 Gif-sur-Yvette, France
Interests: nanomedicine; nanomaterials; heterogeneous catalysis; organic synthesis; supramolecular chemistry

Special Issue Information

Dear Colleagues,

Micelles are spheroidal aggregates obtained from the self-assembly of amphiphilic molecules that have found applications in various fields ranging from the nanometric formulation of drugs to the promotion of aqueous catalysis. Thanks to their easy synthesis, small size, tunable surface chemistry, and high encapsulation capacity, these objects have gathered considerable attention from researchers around the globe.

This Special Issue is dedicated to recent advances in the synthesis, characterization, and application of micellar nano-assemblies.

The aim is thus to gather research articles dealing with the development of new objects with specific properties (e.g., controlled degradation, novel surface chemistry) or with new applications of micelles in various fields (e.g., nanomedicine, catalysis, smart materials). Review articles that cover specific types of micelles (e.g., polymer micelles, stimuli-responsive micelles) or particular fields of application (e.g., anti-bacterial treatment, green chemistry) and the preparation and/or application of micelles are also expected.

Authors are invited to submit articles that tackle micelle-related topics with emphasis on varied aspects such as physicochemical properties, chemical synthesis, biological impact, catalytic activity or any feature relevant to their research activity.

Dr. Edmond Gravel
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • Micelles
  • Nanomedicine
  • Catalysis
  • Smart materials
  • Self-assembly

Published Papers (1 paper)

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Review

21 pages, 873 KiB  
Review
Polymeric Micelles in Cancer Immunotherapy
by Zhuoya Wan, Ruohui Zheng, Pearl Moharil, Yuzhe Liu, Jing Chen, Runzi Sun, Xu Song and Qiang Ao
Molecules 2021, 26(5), 1220; https://doi.org/10.3390/molecules26051220 - 25 Feb 2021
Cited by 21 | Viewed by 3301
Abstract
Cancer immunotherapies have generated some miracles in the clinic by orchestrating our immune system to combat cancer cells. However, the safety and efficacy concerns of the systemic delivery of these immunostimulatory agents has limited their application. Nanomedicine-based delivery strategies (e.g., liposomes, polymeric nanoparticles, [...] Read more.
Cancer immunotherapies have generated some miracles in the clinic by orchestrating our immune system to combat cancer cells. However, the safety and efficacy concerns of the systemic delivery of these immunostimulatory agents has limited their application. Nanomedicine-based delivery strategies (e.g., liposomes, polymeric nanoparticles, silico, etc.) play an essential role in improving cancer immunotherapies, either by enhancing the anti-tumor immune response, or reducing their systemic adverse effects. The versatility of working with biocompatible polymers helps these polymeric nanoparticles stand out as a key carrier to improve bioavailability and achieve specific delivery at the site of action. This review provides a summary of the latest advancements in the use of polymeric micelles for cancer immunotherapy, including their application in delivering immunological checkpoint inhibitors, immunostimulatory molecules, engineered T cells, and cancer vaccines. Full article
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