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Metal Nanoparticles and Their Biosensing Applications

A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Nanochemistry".

Deadline for manuscript submissions: closed (30 October 2020) | Viewed by 8151

Special Issue Editor


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Guest Editor
1. School of Environment and Science, Griffith University, Nathan Campus, 170 Kessels Road, Nathan, QLD 4111, Australia
2. Queensland Micro- and Nanotechnology Centre, Griffith University, Nathan Campus, 170 Kessels Road, Nathan, QLD 4111, Australia
Interests: point-of-care devices; molecular diagnostics; microfluidics devices; electrochemical sensors
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Recent advances in nanotechnology and nanomaterials have now given rise to a large number of potentially useful nanomaterials for the development of novel biomolecular sensing methods for disease-specific biomolecules (i.e., biomarkers). In particular, engineered multicomponent and multifunctional magnetic nanomaterials have been widely used in developing robust biosensing methods due to their intrinsic magnetic, electrochemical, and optical properties. However, biosensors that offer the advantages of rapid and sensitive quantification of disease-specific molecules in complex biological samples, easy and alterable biorecognition of ligands, antibodies, and receptor molecules, and unified point-of-care or in-field/on-farm integration, have yet to be achieved. In this Special Issue, we will focus on the major nanomaterials and methods that have been used in developing electrochemical, electromechanical, and optical biosensor strategies for biomedical, agricultural, and environmental applications, highlighting the grand challenges associated with the functionality and analytical performance of these strategies.

Dr. Muhammad J. A. Shiddiky
Guest Editor

Manuscript Submission Information

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Keywords

  • Metal nanoparticles
  • Nanoarchitectured materials
  • Nanomaterials
  • Biosensors
  • Porous nanoparticles
  • Nanozymes
  • Electromechanical devices
  • Optical biosensors

Published Papers (1 paper)

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Review

56 pages, 11018 KiB  
Review
Metal Nanoparticles for Electrochemical Sensing: Progress and Challenges in the Clinical Transition of Point-of-Care Testing
by Tamanna Islam, Md. Mahedi Hasan, Abdul Awal, Md Nurunnabi and A. J. Saleh Ahammad
Molecules 2020, 25(24), 5787; https://doi.org/10.3390/molecules25245787 - 08 Dec 2020
Cited by 32 | Viewed by 7762
Abstract
With the rise in public health awareness, research on point-of-care testing (POCT) has significantly advanced. Electrochemical biosensors (ECBs) are one of the most promising candidates for the future of POCT due to their quick and accurate response, ease of operation, and cost effectiveness. [...] Read more.
With the rise in public health awareness, research on point-of-care testing (POCT) has significantly advanced. Electrochemical biosensors (ECBs) are one of the most promising candidates for the future of POCT due to their quick and accurate response, ease of operation, and cost effectiveness. This review focuses on the use of metal nanoparticles (MNPs) for fabricating ECBs that has a potential to be used for POCT. The field has expanded remarkably from its initial enzymatic and immunosensor-based setups. This review provides a concise categorization of the ECBs to allow for a better understanding of the development process. The influence of structural aspects of MNPs in biocompatibility and effective sensor design has been explored. The advances in MNP-based ECBs for the detection of some of the most prominent cancer biomarkers (carcinoembryonic antigen (CEA), cancer antigen 125 (CA125), Herceptin-2 (HER2), etc.) and small biomolecules (glucose, dopamine, hydrogen peroxide, etc.) have been discussed in detail. Additionally, the novel coronavirus (2019-nCoV) ECBs have been briefly discussed. Beyond that, the limitations and challenges that ECBs face in clinical applications are examined and possible pathways for overcoming these limitations are discussed. Full article
(This article belongs to the Special Issue Metal Nanoparticles and Their Biosensing Applications)
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