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Targeting Cancer Metabolism for the Development of Diagnostic, Therapeutic and Theranostic Agents

A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Medicinal Chemistry".

Deadline for manuscript submissions: closed (15 April 2021) | Viewed by 358

Special Issue Editor


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Guest Editor
Lab of Organic Chemistry and Biochemistry, Chemistry Department, University of Ioannina, Ioannina, Greece
Interests: bioactive compounds; phytochemicals; plant extracts; metabolomics; anticancer compounds
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Cancer cells reprogram metabolic and nutrient acquisition paths to satisfy biosynthetic, redox, and bioenergetic demands to support survival, accelerated cell proliferation, and adaptation to the tumor microenvironment. Almost one hundred years have passed since Otto Warburg revealed that an altered metabolism in cancer cells influences their growth. Although cancer metabolism is considered to be one of the oldest research areas in cancer biology and a hallmark of cancer, it has not been fully exploited or explored for the development of novel and effective cancer therapeutic, diagnostic, or theranostic strategies. In order for this to be achieved, orchestrated action, on a system-wide scale, is required for cancer metabolome and proteome cartography through state-of-the-art analytic techniques. Furthermore, we need novel chemical biology tools in order to interrogate the metabolic reprogramming in tumor cells and the mechanistic details that connect the altered cancer cell metabolism to metastasis and tumorigenesis.

How metabolism is reprogrammed in cancer cells, how this can be exploited for the development of therapeutics, diagnostics, and theranostics, and how cancer-altered biochemical paths can be probed will be among the topics that will be covered in this Special issue. Focus will also be placed on multimodal imaging agents (for MRI, in vivo near-infrared I and II optical imaging, SPECT/PET, and photoacoustics) that target and respond to the tumor microenvironment of cancer cells or report on the reprogrammed metabolic pathway of cancer cells.

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the Special Issue’s website. Research articles, review articles, and short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Assist. Prof. Dr. Andreas Tzakos
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • cancer metabolism
  • bioimaging
  • theranostics
  • cancer research.

Published Papers

There is no accepted submissions to this special issue at this moment.
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