Journal Browser

Journal Browser

Special Issue "Plant-Derived Phenolic Compounds: From Molecular Mechanisms to Clinical Application II"

A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Medicinal Chemistry".

Deadline for manuscript submissions: 31 December 2023 | Viewed by 119

Special Issue Editors

Department of Precision and Regenerative Medicine and Ionian Area, University of Bari Aldo Moro, Bari, Italy
Interests: drug delivery using nanoparticles in vitro; cell imaging; cellular models of inflammation; natural antioxidants for airway epithelium; chronic respiratory diseases
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Plant-derived phenolic compounds, whose most important classes are flavonoids (i.e., catechin, epicatechin) quinones, stilbenes (i.e., resveratrol) and essential oils (i.e., thymol, carvacrol), are widely present in fruits, seeds, flowers, and leaves. They are have gained attention over time for the prevention and treatment of several diseases, since it has been shown that they have antioxidant, anti-carcinogenic, cardioprotective, neuroprotective and anti-inflammatory properties. It has been demonstrated that they slow tumor development through the inhibition of cell proliferation and induction of apoptosis. Moreover, they have also proved effective as cardioprotective agents by inhibiting the LDL oxidation involved in the pathogenesis of atherosclerosis. In addition, these have been proven to improve diabetic complications, such as neuropathy, retinopathy, or nephropathy. Phenolic compounds present strong antimicrobial activity, i.e., providing antiadhesive actions against bacteria in urinary and dental infections. Finally, these compounds can increase the migration of mesenchymal stem cells (MSCs) and enhance wound healing by regulating the functions and behavior of MSCs during immunomodulation. This Special Issue will shed light on various aspects related to phenolic extracts, and their extraction, synthesis and delivery, collecting contributions concerning advances related to their use in various research fields and novel research works aimed at obtaining new information on the biological features of these molecules in order to understand the mechanisms involved in their protective role, their bioavailability and their metabolism in human tissue.

Dr. Stefano Castellani
Prof. Dr. Massimo Conese
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • phenolic compounds
  • extraction and synthesis
  • oxidative stress
  • inflammation
  • cancer
  • neurodegenerative diseases
  • cardiovascular diseases
  • drug delivery

Published Papers

This special issue is now open for submission.
Back to TopTop