Cold-Adapted Bacteria and Marine Bacteria

A special issue of Microorganisms (ISSN 2076-2607). This special issue belongs to the section "Microbial Biotechnology".

Deadline for manuscript submissions: 31 May 2024 | Viewed by 641

Special Issue Editor


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Guest Editor
Dipartimento di Scienze Chimiche, Università degli Studi di Napoli Federico II, Complesso Universitario Monte S. Angelo, Via Cintia 4, 80126 Napoli, Italy
Interests: Pseudoalteromonas haloplanktis genetics and genomics; psychrophilic bacteria fermentation; psychrophilic bacteria physiology; bioactive compounds from marine bacteria; recombinant protein production in Pseudoalteromonas haloplanktis
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Special Issue Information

Dear Colleagues,

This Special Issue is the continuation of our previous Special Issue, entitled "Biotechnology of Cold-Adapted Bacteria and Marine Bacteria", which was published in 2021:

Permanent or transient cold environments are prevalent on our planet. Indeed, besides the polar and alpine areas, a large portion of seawater has a temperature below 15 °C. We are approaching the study of the microbiome that thrives in these habitats, uncovering a “world of opportunities” for biotechnologists.

This Special Issue aims to report the cutting-edge applications of microorganisms isolated from sea and/or from cold environments, their enzymes, and their chemical diversity in different fields of modern biotechnologies, such as (and not limited to) the following:

  • Food applications;
  • Detergents and the cleaning industry;
  • Environmental biotechnologies (wastewater treatments and bioremediation);
  • Biofuels and energy production;
  • Molecular as well as structural biology and recombinant protein production;
  • Pharmaceutical and medical industry.

Dr. Maria Luisa Tutino
Guest Editor

Manuscript Submission Information

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Keywords

  • cold-adapted enzyme
  • cold-adapted bacteria
  • marine bacteria
  • white biotechnologies
  • enzyme catalysis
  • microbial catalysis
  • food biotechnologies
  • environmental biotechnologies
  • detergent industry
  • cleaning industry
  • biofuels
  • molecular biology
  • recombinant protein production
  • pharmaceutical industry
  • structural biology

Published Papers (1 paper)

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Research

12 pages, 2173 KiB  
Article
Exploring the Frozen Armory: Antiphage Defense Systems in Cold-Adapted Bacteria with a Focus on CRISPR-Cas Systems
by Greta Daae Sandsdalen, Animesh Kumar and Erik Hjerde
Microorganisms 2024, 12(5), 1028; https://doi.org/10.3390/microorganisms12051028 - 20 May 2024
Viewed by 482
Abstract
Our understanding of the antiphage defense system arsenal in bacteria is rapidly expanding, but little is known about its occurrence in cold-adapted bacteria. In this study, we aim to shed light on the prevalence and distribution of antiphage defense systems in cold-adapted bacteria, [...] Read more.
Our understanding of the antiphage defense system arsenal in bacteria is rapidly expanding, but little is known about its occurrence in cold-adapted bacteria. In this study, we aim to shed light on the prevalence and distribution of antiphage defense systems in cold-adapted bacteria, with a focus on CRISPR-Cas systems. Using bioinformatics tools, Prokaryotic Antiviral Defense LOCator (PADLOC) and CRISPRCasTyper, we mapped the presence and diversity of antiphage defense systems in 938 available genomes of cold-adapted bacteria from diverse habitats. We confirmed that CRISPR-Cas systems are less frequent in cold-adapted bacteria, compared to mesophilic and thermophilic species. In contrast, several antiphage defense systems, such as dXTPases and DRTs, appear to be more frequently compared to temperate bacteria. Additionally, our study provides Cas endonuclease candidates with a potential for further development into cold-active CRISPR-Cas genome editing tools. These candidates could have broad applications in research on cold-adapted organisms. Our study provides a first-time map of antiphage defense systems in cold-adapted bacteria and a detailed overview of CRISPR-Cas diversity. Full article
(This article belongs to the Special Issue Cold-Adapted Bacteria and Marine Bacteria)
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