Gut Microbiota in Disease—Third Edition
A special issue of Microorganisms (ISSN 2076-2607). This special issue belongs to the section "Gut Microbiota".
Deadline for manuscript submissions: 31 July 2024 | Viewed by 66
Special Issue Editor
Interests: gut microbiota; liver disease; hepatocellular carcinoma; liver cirrhosis; nonalcoholic fatty liver disease
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
This Special Issue is a continuation of our previous Special Issue, “Gut Microbiota in Disease”.
The gut microbiota is composed of trillions of microorganisms that reside in our digestive system and perform a number of essential functions for human health. In fact, it constitutes the variable part of our genetic equipement, can be influenced by multiple factors, including drugs or diet, and contributes to the metabolism of nutrients, bile acids and xenobiotics, modulating the host immune system and systemic inflammatory state, and the proper functioning of the intestinal barrier. Perturbations of the intestinal microbiota may underlie the pathogenesis of numerous disease processes not only in the digestive tract, but also the whole organism. Complex alterations in the composition and function of the gut microbiome, collectively defined as dysbiosis, are a crucial point in the progression of pathologies, such as liver cirrhosis, immune-mediated diseases and neurological disorders. Therefore, modulation of the gut microbiome becomes fundamental to stop the progression of several diseases and regulate the response to therapy in specific contexts, such as in cancer patients who are treated with immunotherapy.
The aim of this Special Issue is to report the latest evidence on the role of the gut microbiome in influencing human health, particularly regarding its contribution to various disease processes, and how its modulation may affect the development and progression of diseases.
Dr. Francesca Romana Ponziani
Guest Editor
Manuscript Submission Information
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Keywords
- gut microbiome
- intestinal barrier
- inflammation
- immune system
- antibiotics
- cancer
