Optical Tools for Biomedical Applications

A special issue of Micromachines (ISSN 2072-666X). This special issue belongs to the section "B:Biology and Biomedicine".

Deadline for manuscript submissions: 31 May 2024 | Viewed by 1222

Special Issue Editors


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Guest Editor
Department of Natural Sciences, University of Michigan - Dearborn, Dearborn, MI 48128, USA
Interests: optical tweezers; microscopy; intracellular transport; molecular motors; microtubule; biophysics

E-Mail Website
Guest Editor
Department of Physics, National Central University, Taoyuan City 32001, Taiwan
Interests: optical tweezers; non-equilibrium physics; molecular motors; biophysics

Special Issue Information

Dear Colleagues,

Optical tools offer non-invasive approaches for studying biological samples with high spatiotemporal resolutions. The development of the present and future generations of medical instruments and techniques for diagnostic, therapy, and surgical applications rely on the power of optics. New techniques and instruments lead to new discoveries and open new avenues to diagnose biological problems. This Special Issue, "Optical Tools for Biomedical Applications", is a platform to show high-quality research and new technological development in the field of biomedical optics. The aim of this Issue is to collect a broad range of innovations in diagnostic methods and devices such as optical microscopy, optical tweezers, fiber-optics, optical coherence tomography, multi-modal imaging, methods in cancer diagnostics, detection of infectious disease, and any other instrumentation developments in the field biomedical optics. The Special Issue will accept all forms of contributions, including research papers, communications, methods, and review articles that represent the current state of the art in biomedical optics.

Dr. Suvranta Tripathy
Prof. Dr. Yonggun Jun
Guest Editors

Manuscript Submission Information

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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • biomedical optics
  • medical imaging
  • optical tweezers
  • biophotonics
  • optical coherence tomography
  • fiber-optics
  • microscopy
  • image processing
  • Raman spectroscopy

Published Papers (1 paper)

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Research

11 pages, 13258 KiB  
Article
Investigating the Influence of Probe Pressure on Human Skin Using Diffusive Reflection Spectroscopy
by Israr Ahmed, Murad Ali and Haider Butt
Micromachines 2023, 14(10), 1955; https://doi.org/10.3390/mi14101955 - 20 Oct 2023
Viewed by 793
Abstract
The skin has emerge as a compelling subject for investigation owing to its accessibility and the relatively straightforward application of optical procedures to it. Diffusive reflection spectroscopy (DRS) was employed to study the influence of probe pressure on human skin. A comprehensive non-invasive [...] Read more.
The skin has emerge as a compelling subject for investigation owing to its accessibility and the relatively straightforward application of optical procedures to it. Diffusive reflection spectroscopy (DRS) was employed to study the influence of probe pressure on human skin. A comprehensive non-invasive study was conducted, which covers almost all the important body parts for in vivo measurements. Reflection spectra were measured for the fingertip, forearm, forehead, neck, and foot under a set of probe pressures (0–265 kPa). Importantly, each tissue type’s unique composition and morphology influenced the shape, size, intensity, and position of the recorded peak, highlighting the tissue-specific responses to pressure. In addition, time-based reflection spectroscopy was also performed on the forearm under blood occlusion for 5 min to study the effect. DRS measurements were performed on volunteers of different skin tones, including dark, medium, and fair. Later, a change in the intensity of the oxyhemoglobin peak was confirmed using a green laser light of a wavelength of 532 nm. Besides the dermal studies, diffusive reflection spectroscopy was also employed to investigate the probe pressure effect on human nails. A probe pressure ranging from 0 to 385 kPa was applied for nail spectroscopy. The same trend of intensity change was observed following the previous measurements. The suggested sensing system may be crucial in applications requiring pressure sensing when the human body is subjected to varying pressures, such as exercise, weightlifting, and other sports. Full article
(This article belongs to the Special Issue Optical Tools for Biomedical Applications)
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