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Micromachines
Special Issues
Feature Papers of Micromachines in Chemistry 2020
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Feature Papers of Micromachines in Chemistry 2020

A special issue of Micromachines (ISSN 2072-666X). This special issue belongs to the section "C：Chemistry".

Deadline for manuscript submissions: closed (31 December 2020) | Viewed by 27904

Special Issue Editors

Prof. Dr. Xiujun Li

E-Mail Website
Guest Editor
Department of Chemistry, University of Texas at El Paso, El Paso, TX 79968, USA
Interests: microfluidics; lab-on-a-chip; nanotechnology; bioanalytical chemistry; infectious disease diagnosis; biomarker detection; cellular analysis; environmental science & technology; catalysis
Prof. Dr. Manabu Tokeshi

E-Mail Website
Guest Editor
Division of Applied Chemistry, Faculty of Engineering, Hokkaido University, Kita 13 Nishi 8, Kita-ku, Sapporo 060-8628, Japan
Interests: microfluidic/nanofluidic devices; lab on a chip; micro total analysis systems; ultrasensitive detection
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

We are pleased to announce the Special Issue entitled "Feature Papers of Micromachines in Chemistry 2020". In the past several years, we cooperated with excellent scholars and research groups to publish several high-impact high-quality works, which have already been cited according to Web of Science. We aim to introduce a new insight into science development or cutting-edge technology related to micromachines in the fields of biology and biomedical sciences, which will make a great contribution to the community.

This Special Issue will be a collection of high-quality papers from excellent scholars around the world. Both original research articles and comprehensive review papers are welcome. The papers will be published, free of charge, with full open access after peer review to benefit both authors and readers.

You are welcome to send short proposals for submissions of Feature Papers to our Editorial Office (micromachines@mdpi.com) before the submission. The proposals will first be evaluated by the Editors. Please note that selected full papers will still be subjected to a thorough and rigorous peer review.

We look forward to receiving your excellent work.

Prof. Dr. Xiujun Li
Prof. Dr. Manabu Tokeshi
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Micromachines is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • Electrochemical devices
  • Nanoelectrodes
  • Miniaturized gas sensors
  • Miniaturized chemical sensors
  • Microsystems for chemistry
  • Microreactors
  • Electrokinetic phenomenon
  • Lab-on-a-chip, biochips, microfluidic applications in chemistry, energy and environmental sciences

Published Papers (4 papers)

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Research

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11 pages, 2273 KiB  
Article
A Mobile Analytical Device for On-Site Quantitation of Anthocyanins in Fruit Beverages
by Mohsen Salimi, Brigitta R. Sun, Jenny Syl Tabunag, Jianxiong Li and Hua-Zhong Yu
Micromachines 2021, 12(3), 246; https://doi.org/10.3390/mi12030246 - 28 Feb 2021
Cited by 5 | Viewed by 1940
Abstract
Anthocyanins are antioxidant and anti-inflammatory ingredients in various fruit beverages, for which their conservation and quantitation are important for the food industry. In this paper, we report a simple, portable device for accurate on-site determination of total monomeric anthocyanins in fruit beverages employing [...] Read more.
Anthocyanins are antioxidant and anti-inflammatory ingredients in various fruit beverages, for which their conservation and quantitation are important for the food industry. In this paper, we report a simple, portable device for accurate on-site determination of total monomeric anthocyanins in fruit beverages employing a Wi-Fi scanner coupled with a flexible microchip and a free mobile app. The detection principle is based on the pH-induced colorimetric reactions of anthocyanins performed in a specially designed microchip and validated with standard spectrophotometric measurements. The microchip with multiple testing vials was prepared with the benchtop molding method with a common PDMS elastomer and a transparency film; the photo of the scanned microchip is wirelessly sent to a smartphone and the RGB values of individual reaction vials in the microchip are analyzed with a free mobile app to determine the corresponding concentrations. It was demonstrated that the quantitation performance of this POCT device is comparable with conventional spectrophotometry in the determination of total anthocyanins in both standard solutions and fruit beverages. Full article
(This article belongs to the Special Issue Feature Papers of Micromachines in Chemistry 2020)
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7 pages, 2121 KiB  
Article
Fabrication of a T-Shaped Microfluidic Channel Using a Consumer Laser Cutter and Application to Monodisperse Microdroplet Formation
by Naoki Sasaki and Eisuke Sugenami
Micromachines 2021, 12(2), 160; https://doi.org/10.3390/mi12020160 - 05 Feb 2021
Cited by 3 | Viewed by 2346
Abstract
The use of micrometer-sized droplets for chemical and biochemical analysis has been widely explored. Photolithography is mainly used to fabricate microfluidic devices, which is often employed to form monodisperse microdroplets. Although photolithography enables precise microfabrication, it is not readily available to biochemists because [...] Read more.
The use of micrometer-sized droplets for chemical and biochemical analysis has been widely explored. Photolithography is mainly used to fabricate microfluidic devices, which is often employed to form monodisperse microdroplets. Although photolithography enables precise microfabrication, it is not readily available to biochemists because it requires specialized equipment such as clean room and mask aligners, and expensive consumables such as photoresist and silicon wafers. In this study, we fabricated a microfluidic device using a consumer laser cutter and applied it to droplet formation. Monodisperse microdroplets were formed by using an oil phase for droplet digital polymerase chain reaction (PCR) as the continuous phase and phosphate-buffered saline or polyethylene glycol solution as the dispersed phase. The droplet size decreased as the flow rate of the continuous phase increased and approached a constant value. The method developed in this study can be used to realize microdroplet-based biochemical analysis with simple devices or to construct artificial cells. Full article
(This article belongs to the Special Issue Feature Papers of Micromachines in Chemistry 2020)
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Review

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38 pages, 4268 KiB  
Review
Fabrication Methods for Microfluidic Devices: An Overview
by Simon M. Scott and Zulfiqur Ali
Micromachines 2021, 12(3), 319; https://doi.org/10.3390/mi12030319 - 18 Mar 2021
Cited by 174 | Viewed by 18280
Abstract
Microfluidic devices offer the potential to automate a wide variety of chemical and biological operations that are applicable for diagnostic and therapeutic operations with higher efficiency as well as higher repeatability and reproducibility. Polymer based microfluidic devices offer particular advantages including those of [...] Read more.
Microfluidic devices offer the potential to automate a wide variety of chemical and biological operations that are applicable for diagnostic and therapeutic operations with higher efficiency as well as higher repeatability and reproducibility. Polymer based microfluidic devices offer particular advantages including those of cost and biocompatibility. Here, we describe direct and replication approaches for manufacturing of polymer microfluidic devices. Replications approaches require fabrication of mould or master and we describe different methods of mould manufacture, including mechanical (micro-cutting; ultrasonic machining), energy-assisted methods (electrodischarge machining, micro-electrochemical machining, laser ablation, electron beam machining, focused ion beam (FIB) machining), traditional micro-electromechanical systems (MEMS) processes, as well as mould fabrication approaches for curved surfaces. The approaches for microfluidic device fabrications are described in terms of low volume production (casting, lamination, laser ablation, 3D printing) and high-volume production (hot embossing, injection moulding, and film or sheet operations). Full article
(This article belongs to the Special Issue Feature Papers of Micromachines in Chemistry 2020)
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16 pages, 3077 KiB  
Review
Methodologies for Fabricating Flexible Supercapacitors
by Seohyeon Jang, Jihyeon Kang, Soyul Kwak, Myeong-Lok Seol, M. Meyyappan and Inho Nam
Micromachines 2021, 12(2), 163; https://doi.org/10.3390/mi12020163 - 07 Feb 2021
Cited by 14 | Viewed by 4324
Abstract
The spread of wearable and flexible electronics devices has been accelerating in recent years for a wide range of applications. Development of an appropriate flexible power source to operate these flexible devices is a key challenge. Supercapacitors are attractive for powering portable lightweight [...] Read more.
The spread of wearable and flexible electronics devices has been accelerating in recent years for a wide range of applications. Development of an appropriate flexible power source to operate these flexible devices is a key challenge. Supercapacitors are attractive for powering portable lightweight consumer devices due to their long cycle stability, fast charge-discharge cycle, outstanding power density, wide operating temperatures and safety. Much effort has been devoted to ensure high mechanical and electrochemical stability upon bending, folding or stretching and to develop flexible electrodes, substrates and overall geometrically-flexible structures. Supercapacitors have attracted considerable attention and shown many applications on various scales. In this review, we focus on flexible structural design under six categories: paper-like, textile-like, wire-like, origami, biomimetics based design and micro-supercapacitors. Finally, we present our perspective of flexible supercapacitors and emphasize current technical difficulties to stimulate further research. Full article
(This article belongs to the Special Issue Feature Papers of Micromachines in Chemistry 2020)
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