Special Issue "Design Principles and Biomedical Applications of Multifunctional Biological Membranes"

A special issue of Membranes (ISSN 2077-0375). This special issue belongs to the section "Biological Membrane Functions".

Deadline for manuscript submissions: 29 February 2024 | Viewed by 167

Special Issue Editors

Institute of Theoretical Physics, Chinese Academy of Sciences, Beijing 100080, China
Interests: fluid membranes; elasticity and geometry of membranes and vesicles; physics of 2D and 3D liquid crystals; elastic folding of DNA biomacromolecules and proteins; nonlinear science; theoretical biophysics and bioinformatics
Wenzhou Institute, University of Chinese Academy of Sciences, Wenzhou 325001, China
Interests: elasticity and geometry of solid/fluid membranes; multicomponent fluid membranes; coarse-grained simulations of membranes and polymers; cell migration and microswimming with/without geometric confinements; fluid-structure interaction; active colloid motors; self-assembly of molecular materials

Special Issue Information

Dear Colleagues,

Biological membranes are essential for life through their compartmentalization into cells and organelles therein. The bilayer structure, composed of various kinds of lipids, membrane proteins and bioactive polymers anchored thereon, can perform many significant biological functions, including biochemical signaling, ion transportation, membrane trafficking and protein scaffolding, morphological change, membrane fission/fusion, and cell motility. Each function requires that a specific group of proteins and lipids with anchored sugar chains rapidly assemble and disassemble at a specific site on membrane surface. Such processes, at the nanoscale, further drive the deformation of membranes or vesicles at the micron level in order to perform physiological and pathological functions. Understanding the design principles underneath these rich phenomena is critical to controlling various functions of biological membranes and applying their multiple functions to a broad range of artificial membranes and liposomes, stimuli reponsive functional materials, medical soft materials, and even physiological and pathological processes, such as intracellular signaling pathway, endocytosis/exocytosis, and immunomodulatory processes.

This Special Issue focuses on the recent developments regarding theory, simulation and experiments focused on biological membranes interacting with complex environments, such as external fields, BAR protein regulation, phase separation and viscous fluid, and the novel applications emerging from such studies. At present, their applications are constrained by many open questions regarding the diversity of components, heterogeneity of membrane structures, non-equilibrium thermodynamics, nonlinear elasticity and their interaction with complex environments, which are under intense investigation.

Prof. Dr. Zhongcan Ouyang
Prof. Dr. Hao Wu
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Membranes is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • cell membranes
  • solid membranes
  • fluid membranes
  • multicomponent membranes
  • bioactive membranes
  • external fields
  • external flows
  • endocytosis/exocytosis
  • membrane fusion/fission
  • membrane budding
  • pattern formation
  • phase separation
  • lipid rafts
  • lipid-lipid interactions
  • lipid-protein interactions
  • protein-protein interactions
  • drug-membrane interactions
  • nanoparticle-membrane interactions
  • transmembrane ion channels
  • signal transduction
  • membrane structure and organization
  • mathematical modeling
  • numerical simulations
  • intracellular communication
  • extracellular vesicles
  • ion regulation
  • geometric confinements
  • extracellular matrix
  • protein scaffolding
  • membrane trafficking
  • cytoskeleton network
  • cortical layers

Published Papers

This special issue is now open for submission, see below for planned papers.

Planned Papers

The below list represents only planned manuscripts. Some of these manuscripts have not been received by the Editorial Office yet. Papers submitted to MDPI journals are subject to peer-review.

  1. Tentative Title: Deformation theory of tubluar giant vesicles under external magnetic field

Authors: Hao Wu and Zhong-Can Ou-Yang

  1. Tentative Title: Generalized Helfrich free energy of multicomponent fluid membranes

Author: Hao Wu

  1. Tentative Title: Behaviors of elastic membranes in complex environments

Authors: Hao Wu and Zhong-Can Ou-Yang

  1. Tentative Title: Immunomodulatory Applications of Cell Membrane-coated Nanoparticles

Author: Nimeet Desai, Indian Institute of Technology Hyderabad

  1. Dr. Guoye Guan, Peking University
  2. Prof. Mathias Winterhalter, Constructor University Bremen, Bremen, Germany
  3. Dr. Lisa Skverchinskaya, Sechenov Institute of Evolutionary Physiology and Biochemistry of the Russian Academy of Sciences, Russia
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