Marine-Derived Vaccine Adjuvants
A special issue of Marine Drugs (ISSN 1660-3397).
Deadline for manuscript submissions: closed (17 January 2020) | Viewed by 3460
Special Issue Editor
Interests: structure and function of biological membranes; lipids; phase transitons; marine hydrobionts; bacteria; adaptation; antibiotic resistance; lipid-dependent conformation and functions of proteins; lipochaperoning; vaccines; adjuvant vehicles; recombinant proteins; viruses; nanobiotechnology; immunology
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
An immunological (vaccine) adjuvant is a substance or complex of substances that is added to vaccines to boost immune responses to the target antigens. Modern vaccinology is focused on the development of subunit vaccines containing a protective antigen of the pathogen to minimise the risk of adverse effects. Therefore, subunit vaccines are safer than traditional ones, which comprise killed or attenuated whole pathogens. However, most antigens administered alone possess very weak immunogenicity and are unable to provide protection against pathogens. Adjuvants allow one to overcome this problem by enhancing the immunogenicity of antigens and improving the effectiveness of vaccines. Therefore, adjuvants also provide the increased economic effect of vaccination. There are different types of adjuvants: aluminum-based adjuvants, emulsions, lipid-based (ISCOMATRIX, TI-complexes, and liposomes), and polymeric particles, etc. In spite of a wide arsenal of available adjuvants, only few of them are suitable for medical and veterinary vaccines. Hence, the elaboration of new adjuvants, which are more effective and safer, is an urgent problem of vaccinology. Marine organisms are abundant in biologically active substances. Some of them possess an adjuvant activity (a-galactosylceramide, originally isolated from a marine sponge, marine crustacean chitosan, and saponins, and proteins isolated from marine animals, etc.). The main goal of this Special Issue “Marine-Derived Vaccine Adjuvants” is to summarise the achievements in the field of the search for substances of marine origin and their semi-synthetic derivatives that possess adjuvant activity. Research articles and reviews devoted to mechanisms of actions of such adjuvants are also welcome.
Dr. Nina M. Sanina
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Marine Drugs is an international peer-reviewed open access monthly journal published by MDPI.
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Keywords
- Adjuvants
- Marine organisms
- Tubular immunostimulating complexes
- Lipid-induced immunogenicity of antigens
