Lipid-Derived Secondary Metabolites from Phytoplankton: Chemical and Functional Diversity

A special issue of Marine Drugs (ISSN 1660-3397).

Deadline for manuscript submissions: closed (15 March 2022) | Viewed by 4342

Special Issue Editors


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Guest Editor
Integrative Marine Ecology Department, Stazione Zoologica Anton Dohrn, Naples, Italy
Interests: marine biology; marine ecology; gene expression; copepods
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Guest Editor
Marine Biotechnology Department, Stazione Zoologica Anton Dohrn, 80121 Naples, Italy
Interests: diatoms; microalgae; molecular biology and biochemistry; bioinformatics; pharmacological and nutraceutical activity
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Phytoplankton species are a rich source of primary metabolites such as carbohydrate and lipids, thus, supporting marine food webs in planktonic and benthic ecosystems, fisheries, aquaculture, and, ultimately, biogeochemical cycles through sinking and degradation. However, lipids are also the main chemical source of numerous bioactive secondary metabolites that play important roles as chemical mediators in algal–algal communication, allelopathy, microzooplankton and mesozooplankton grazer defense, prey–predator recognition. Among them are oxylipins, derived from the lipoxygenase-mediated oxygenation of free fatty acids, functioning as infochemicals in prey–prey and prey–predator interactions. Recently, prostaglandins, hormone-like mediators that play a role in inflammatory responses as well as in many other physiological processes in animals, have also been identified in marine microeukaryotes such as diatoms. However, the biological and ecological role of these molecules in the phytoplankton are still unknown.

This Special Issue will explore the chemical diversity of lipid-derived secondary metabolites produced by phytoplankton in response to different abiotic, physiological, and genetic factors, and also highlight the variety of biological and ecological function they may have on marine organisms. In addition, the Special Issue encourages studies that investigate the production of these metabolites in natural phytoplankton communities, to help to better estimate their potential ecological role at sea.


Dr. Ylenia Carotenuto
Dr. Valeria Di Dato
Guest Editors

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Keywords

  • Phytoplankton
  • Lipids
  • Chemical communication
  • Functional plasticity
  • Defense
  • Allelopathy
  • Secondary metabolites
  • Molecular ecology
  • Chemical structure
  • Network interactions

Published Papers (1 paper)

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Research

18 pages, 6599 KiB  
Article
Year-Round Cultivation of Tetraselmis sp. for Essential Lipid Production in a Semi-Open Raceway System
by Won-Kyu Lee, Yong-Kyun Ryu, Woon-Yong Choi, Taeho Kim, Areumi Park, Yeon-Ji Lee, Younsik Jeong, Choul-Gyun Lee and Do-Hyung Kang
Mar. Drugs 2021, 19(6), 314; https://doi.org/10.3390/md19060314 - 28 May 2021
Cited by 12 | Viewed by 3498
Abstract
There is increasing demand for essential fatty acids (EFAs) from non-fish sources such as microalgae, which are considered a renewable and sustainable biomass. The open raceway system (ORS) is an affordable system for microalgae biomass cultivation for industrial applications. However, seasonal variations in [...] Read more.
There is increasing demand for essential fatty acids (EFAs) from non-fish sources such as microalgae, which are considered a renewable and sustainable biomass. The open raceway system (ORS) is an affordable system for microalgae biomass cultivation for industrial applications. However, seasonal variations in weather can affect biomass productivity and the quality of microalgal biomass. The aim of this study was to determine the feasibility of year-round Tetraselmis sp. cultivation in a semi-ORS in Korea for biomass and bioactive lipid production. To maximize biomass productivity of Tetraselmis sp., f medium was selected because it resulted in a significantly higher biomass productivity (1.64 ± 0.03 g/L) and lower omega-6/omega-3 ratio (0.52/1) under laboratory conditions than f/2 medium (0.70/1). Then, we used climatic data-based building information modeling technology to construct a pilot plant of six semi-ORSs for controlling culture conditions, each with a culture volume of 40,000 L. Over 1 year, there were no significant variations in monthly biomass productivity, fatty acid composition, or the omega-6/omega-3 ratio; however, the lipid content correlated significantly with photosynthetic photon flux density. During year-round cultivation from November 2014 to October 2017, areal productivity was gradually increased by increasing medium salinity and injecting CO2 gas into the culture medium. Productivity peaked at 44.01 g/m2/d in October 2017. Throughout the trials, there were no significant differences in average lipid content, which was 14.88 ± 1.26%, 14.73 ± 2.44%, 12.81 ± 2.82%, and 13.63 ± 3.42% in 2014, 2015, 2016, and 2017, respectively. Our results demonstrated that high biomass productivity and constant lipid content can be sustainably maintained under Korean climate conditions. Full article
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