Special Issue "Bioactive Compounds from Natural Immune Systems of Marine Invertebrates"

A special issue of Marine Drugs (ISSN 1660-3397). This special issue belongs to the section "Marine Pharmacology".

Deadline for manuscript submissions: 31 December 2023 | Viewed by 106

Special Issue Editor

Dipartimento di Scienze e Tecnologie Biologiche, Chimiche e Farmaceutiche, Università di Palermo, Via Archirafi 18, Palermo, 90128, Italy
Interests: immunity; marine invertebrates; cell biology

Special Issue Information

Dear Colleagues,

The immune response is an integrated system of biological processes and structures in invertebrates that recognizes and fights pathogens. This defense mechanism relies on several classes of immune receptors, which sense pathogen-associated molecular patterns and induce sophisticated signaling and cell involvement, based on dynamic feedback-regulated interactions among a number of components (genes, transcripts, metabolites, and proteins). Further studies of the natural immune mechanisms of marine invertebrates need to cover the knowledge gaps regarding the hierarchically organized set of molecular, cellular, and organismal networks involved in these universal immune interactions with pathogens. Natural immune response studies in marine invertebrates, through a wide-ranging approach (transcriptomic, miRNome analysis, proteomics, metabolomics, and in silico analyses), are a keystone to better understand the complexity of the net underlying an immune response and identify the novel potential bioactive molecules used to design and develop new bioactive compounds. In fact, in the last year, aquatic invertebrates have become a major source of biomaterials and bioactive natural products that can have antiviral, anti-inflammatory, anti-cancers, neuroactive, nutraceutics, cosmetics, antibiotics, antifouling products, biomaterials, and even food storage applications.

In this Special Issue, we welcome all types of studies addressing natural immune response molecules, non-coding RNAs, mechanisms, and signaling and regulation pathways that can lead to identifying bioactive molecules in marine invertebrates derived via experimental and in silico research.

Prof. Aiti Vizzini
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Marine Drugs is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • innate immunity
  • marine invertebrate
  • transcriptomic
  • non-coding RNAs
  • proteomics
  • metabolomic
  • in silico analyses
  • marine natural products

Published Papers

This special issue is now open for submission.
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