Toxins as Marine-Based Drug Discovery, 2nd Edition

A special issue of Marine Drugs (ISSN 1660-3397). This special issue belongs to the section "Marine Toxins".

Deadline for manuscript submissions: 30 November 2024 | Viewed by 35

Special Issue Editor


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Guest Editor
Toxicology and Pharmacology, Department Pharmaceutical Sciences, Catholic University Leuven, Herestraat 49 Box 922, 3000 Leuven, Belgium
Interests: peptide toxin; small molecules; voltage-gated ion channel; electrophysiology; pharmacology; venom; drug discovery
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Special Issue Information

Dear Colleagues,

Following the success of the Special Issue “Toxins as Marine-Based Drug Discovery”, we are delighted to launch a second edition on the same topic.

Marine organisms can be considered an untapped cocktail of biologically active compounds, being increasingly recognized as new emerging source of therapeutics. Marine organisms have evolved the most sophisticated peptide chemistry and neuropharmacology for their own biological purposes by producing diverse structural and functional neurotoxins. These neurotoxins are highly selective ligands for a wide range of ion channels and receptors; therefore, they represent interesting lead compounds for the development of, for example, analgesics, anti-cancer drugs and drugs for neurological disorders such as multiple sclerosis, Parkinson's disease, Alzheimer's disease, etc.

This Special Issue of Marine Drugs aims to provide a comprehensive overview of marine toxins and toxin-inspired leads, focusing on the mechanisms of action and structure-function of marine neurotoxins and their targets, including, but not limited to, recent developments relating to the emergence of marine organisms as an underutilized source of highly evolved bioactive peptides and small molecules with a clinical potential.

As the Guest Editor, I invite colleagues working on marine bioactive peptides and compounds to contribute to this Special Issue of Marine Drugs with interesting papers highlighting the significant advances in this field.

Dr. Steve Peigneur
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Marine Drugs is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • neurotoxins
  • marine natural compounds
  • sodium channels
  • potassium channels
  • calcium channels
  • chloride ion channels
  • TRP channels
  • ASIC channels
  • opiate receptors
  • acetylcholine receptors
  • NMDA receptors
  • antibiotics
  • antimicrobial peptides
  • gastropod venom peptides
  • sea anemone toxins

Related Special Issue

Published Papers

This special issue is now open for submission.
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