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Vascular Repair and Remodeling in Health and Disease
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Vascular Repair and Remodeling in Health and Disease

A special issue of Journal of Personalized Medicine (ISSN 2075-4426). This special issue belongs to the section "Regenerative Medicine and Therapeutics".

Deadline for manuscript submissions: closed (30 November 2023) | Viewed by 5300

Special Issue Editor

Dr. Ming Tao

E-Mail Website
Guest Editor
Department of Surgery, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, USA
Interests: regeneration; microvascular dysfunction; remodeling; H2S; gender; vascular progenitor; local delivery; engineered vascular conduit; metabolic disorders; environment factors

Special Issue Information

Dear Colleagues,

We are soliciting contributions from experts in the field of vascular science and technology. In this Special Issue, we aim to bring together a collection of state-of-the-art articles that address vascular therapeutic innovation, challenges, and significant contributions to combating the prevalence and incidence of cardiovascular disease. This Special Issue will focus on vascular remodeling and repair in physiological and pathological conditions, covering vascular response to injury and hemodynamic perturbations, especially in obese and ageing populations; the discovery of vascular diseases in different genders and the underlying cellular and molecular mechanisms; how adipose tissue contributes to homeostatic vascular physiology and the pathogenesis of cardiovascular disease as well as how vessels interact with their microenvironment; vascular degradation and regeneration; microcirculatory dysfunction and adventitia remodeling/fibrosis; local delivery technology; advanced lineage-tracing techniques, especially novel methods to track vascular progenitor cells and their fate; and tissue-engineered vascular conduits. Original research investigations and review papers are welcome. Papers will be published in MDPI (Multidisciplinary Digital Publishing Institute, Journal of Personalized Medicine, impact factor = 3.508).

Dr. Ming Tao
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Personalized Medicine is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • regeneration
  • microvascular dysfunction
  • remodeling
  • H2S
  • gender
  • vascular progenitor
  • local delivery
  • engineered vascular conduit
  • metabolic disorders
  • environment factors

Published Papers (2 papers)

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Research

13 pages, 672 KiB  
Article
Efficacy and Safety of Axiostat® Hemostatic Dressing in Aiding Manual Compression Closure of the Femoral Arterial Access Site in Patients Undergoing Endovascular Treatments: A Preliminary Clinical Experience in Two Centers
by Roberto Minici, Raffaele Serra, Claudio Maglia, Giuseppe Guzzardi, Marco Spinetta, Federico Fontana, Massimo Venturini and Domenico Laganà
J. Pers. Med. 2023, 13(5), 812; https://doi.org/10.3390/jpm13050812 - 11 May 2023
Cited by 5 | Viewed by 2137
Abstract
Background: Hemostasis of the femoral arterial access site by manual compression or a vascular closure device is critical to the safe completion of any endovascular procedure. Previous investigations evaluated the hemostatic efficacy at the radial access site of some chitosan-based hemostatic pads. This [...] Read more.
Background: Hemostasis of the femoral arterial access site by manual compression or a vascular closure device is critical to the safe completion of any endovascular procedure. Previous investigations evaluated the hemostatic efficacy at the radial access site of some chitosan-based hemostatic pads. This study aims to assess the efficacy and safety of a new chitosan-based hemostatic dressing, namely Axiostat®, in aiding manual compression closure of the femoral arterial access site in patients undergoing endovascular treatments. Furthermore, the outcomes were compared with evidence on manual compression alone and vascular closure devices. Methods: This investigation is a two-center retrospective analysis of 120 consecutive patients who had undergone, from July 2022 to February 2023, manual compression closure of the femoral arterial access site aided by the Axiostat® hemostatic dressing. Endovascular procedures performed with introducer sheaths ranging from 4 Fr to 8 Fr were evaluated. Results: Primary technical success was achieved in 110 (91.7%) patients, with adequate hemostasis obtained in all cases of prolonged manual compression requirements. The mean time-to-hemostasis and time-to-ambulation were 8.9 (±3.9) and 462 (±199) minutes, respectively. Clinical success was achieved in 113 (94.2%) patients, with bleeding-related complications noted in 7 (5.8%) patients. Conclusions: Manual compression aided by the Axiostat® hemostatic dressing is effective and safe in achieving hemostasis of the femoral arterial access site in patients undergoing endovascular treatment with a 4–8 Fr introducer sheath. Full article
(This article belongs to the Special Issue Vascular Repair and Remodeling in Health and Disease)
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16 pages, 2896 KiB  
Article
Efficacy and Safety of Distal Radial Access for Transcatheter Arterial Chemoembolization (TACE) of the Liver
by Roberto Minici, Raffaele Serra, Marco Giurdanella, Marisa Talarico, Maria Anna Siciliano, Gianpaolo Carrafiello and Domenico Laganà
J. Pers. Med. 2023, 13(4), 640; https://doi.org/10.3390/jpm13040640 - 07 Apr 2023
Cited by 10 | Viewed by 2851
Abstract
Background: The distal radial artery has emerged as an alternative vascular-access site to conventional transfemoral and transradial approaches. The main advantage over the conventional transradial route is the reduced risk of radial artery occlusion, especially in those patients who, for various clinical reasons, [...] Read more.
Background: The distal radial artery has emerged as an alternative vascular-access site to conventional transfemoral and transradial approaches. The main advantage over the conventional transradial route is the reduced risk of radial artery occlusion, especially in those patients who, for various clinical reasons, have to undergo repeated endovascular procedures. This study aims to assess the efficacy and safety of distal radial access for transcatheter arterial chemoembolization of the liver. Methods: This investigation is a single-center retrospective analysis of 42 consecutive patients who had undergone, from January 2018 to December 2022, transcatheter arterial chemoembolization of the liver with distal radial access for intermediate-stage hepatocellular carcinoma. Outcome data were compared with a retrospectively constituted control group of 40 patients undergoing drug-eluting beads-transcatheter arterial chemoembolization with femoral access. Results: Technical success was achieved in all cases, with a 2.4% conversion rate for distal radial access. A superselective chemoembolization was performed in 35 (83.3%) cases of distal radial access. No episode of radial artery spasm or radial artery occlusion occurred. No significant differences in efficacy and safety were observed between the distal radial access group and the femoral access group. Conclusions: Distal radial access is effective, safe, and comparable to femoral access in patients undergoing transcatheter arterial chemoembolization of the liver. Full article
(This article belongs to the Special Issue Vascular Repair and Remodeling in Health and Disease)
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