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Biotechnological Valorization of Marine Resources and By-Products
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Biotechnological Valorization of Marine Resources and By-Products

A special issue of Journal of Marine Science and Engineering (ISSN 2077-1312). This special issue belongs to the section "Marine Biology".

Deadline for manuscript submissions: closed (29 February 2020) | Viewed by 27170

Special Issue Editor

Dr. Ana P. Carvalho

E-Mail Website1 Website2
Guest Editor
CBQF–Centro de Biotecnologia e Química Fina–Laboratório Associado, Universidade Católica Portuguesa, Escola Superior de Biotecnologia, Rua Diogo Botelho 1327, 4169-005 Porto, Portugal
Interests: by-product valorisation; green extraction processes; functional ingredients; marine bioactive lipids; microalgae; omega-3 fatty acids
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Despite the steadily-declining stocks of marine species, a major portion of harvested fish and marine invertebrates is discarded or redirected to the production of low-value fishmeal. However, marine by-products contain valuable protein and lipid fractions, as well as specific enzymes and other bioactive compounds, which may be extremely interesting for food, cosmetic, and pharmaceutical industries. Therefore, the search for environmentally and economically-sustainable alternatives for the full utilization of the catch and processing of marine discards, aiming at the production of novel products, is of utmost importance. Moreover, there is a great potential to obtain valuable ingredients from several marine resources, such as microalgae and seaweeds.

This Special Issue intends to revisit the current research done on the valorization of marine resources and by-products, in order to obtain high added-value compounds. Topics within its scope include advances in green extraction processes, isolation and purification of marine-sourced compounds, bioactivity assays using extracts from marine resources and by-products, and their incorporation into food, cosmetic and pharmaceutical products.

As Guest Editor of this Special Issue, I cordially invite researchers to submit original research articles, long and mini reviews, and short notes on their current research, encompassing the biotechnological recovery, processing and applications of marine by-products and resources.

Dr. Ana P. Carvalho
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Marine Science and Engineering is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • By-products valorization
  • High added-value compounds
  • Green extraction technologies
  • Concentration and purification of marine-sourced compounds
  • Bioactivity assays
  • Incorporation in food, cosmetic and pharmaceutical products

Published Papers (4 papers)

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Research

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13 pages, 1801 KiB  
Article
Cell-Free Coelomic Fluid Extracts of the Sea Urchin Arbacia lixula Impair Mitochondrial Potential and Cell Cycle Distribution and Stimulate Reactive Oxygen Species Production and Autophagic Activity in Triple-Negative MDA-MB231 Breast Cancer Cells
by Claudio Luparello, Debora Ragona, Dalia Maria Lucia Asaro, Valentina Lazzara, Federica Affranchi, Vincenzo Arizza and Mirella Vazzana
J. Mar. Sci. Eng. 2020, 8(4), 261; https://doi.org/10.3390/jmse8040261 - 07 Apr 2020
Cited by 15 | Viewed by 3453
Abstract
Triple-negative breast cancer (TNBC) is a highly malignant tumor histotype which lacks effective targeted therapies, thereby being considered as the most aggressive form of breast carcinoma. To identify novel compounds which could counteract TNBC cell growth, we explored the in vitro effects of [...] Read more.
Triple-negative breast cancer (TNBC) is a highly malignant tumor histotype which lacks effective targeted therapies, thereby being considered as the most aggressive form of breast carcinoma. To identify novel compounds which could counteract TNBC cell growth, we explored the in vitro effects of crude extracts and <10 kDa-filtered fractions of the coelomic fluid obtained from the sea urchin Arbacia lixula on TNBC MDA-MB231 cells. We examined cell viability, cycle distribution, apoptotic/autophagic activity, and mitochondrial polarization/cell redox status. Here, we report the first data demonstrating an anti-TNBC effect by A. lixula-derived coelomic fluid extracts. Thus, identification of the water-soluble bioactive component(s) contained in the extracts deserve(s) further investigation aimed to devise novel promising prevention and/or treatment agents effective against highly malignant breast tumors. Full article
(This article belongs to the Special Issue Biotechnological Valorization of Marine Resources and By-Products)
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11 pages, 295 KiB  
Article
Mineral Composition of Subcritical Water Extracts of Saccorhiza Polyschides, a Brown Seaweed Used as Fertilizer in the North of Portugal
by Cristina Soares, Jaroslava Švarc-Gajić, Maria Teresa Oliva-Teles, Edgar Pinto, Nataša Nastić, Saša Savić, Agostinho Almeida and Cristina Delerue-Matos
J. Mar. Sci. Eng. 2020, 8(4), 244; https://doi.org/10.3390/jmse8040244 - 02 Apr 2020
Cited by 23 | Viewed by 3500
Abstract
The present work aimed at studying Saccorhiza polyschides extracts obtained by subcritical water extraction as a potential source of essential macro and trace elements, aiming for its potential application as a biofertilizer. The mineral composition, as well as sulfate, chlorine and iodine, total [...] Read more.
The present work aimed at studying Saccorhiza polyschides extracts obtained by subcritical water extraction as a potential source of essential macro and trace elements, aiming for its potential application as a biofertilizer. The mineral composition, as well as sulfate, chlorine and iodine, total organic matter, and total nitrogen content, were determined on the extracts obtained from seaweeds harvested during low tide at the northern Portuguese coast. The selected parameters are important for a biofertilizer. Among the macronutrients, the most abundant was K (15.7 ± 0.2 g/L), followed by Na (5.46 ± 0.11 g/L), S (1.52 ± 0.06 g/L), Ca (1.09 ± 0.11 g/L), and Mg (1.02 ± 0.08 g/L). Several important micronutrients (Zn, B, Cl, P, Mo, V, Se, and I) have also been found in the extracts. The total organic matter was 34.1 ± 0.3 g/L. The extracts present low levels of toxic compounds such as Ni, Cd, and Pb. Considering the composition of the obtained extracts, these can find application in the development of fertilization products. The composition of subcritical water extracts of S. polyschides suggests that they may have important characteristics as a biofertilizer and can be an option in biofortification experiments with essential nutrients. The method can be easily scaled up which makes it attractive for agricultural applications. Full article
(This article belongs to the Special Issue Biotechnological Valorization of Marine Resources and By-Products)
14 pages, 1759 KiB  
Article
Extraction and Analysis of Compounds with Antibacterial Potential from the Red Alga Grateloupia turuturu
by Isabel Cardoso, João Cotas, Ana Rodrigues, Daniel Ferreira, Nádia Osório and Leonel Pereira
J. Mar. Sci. Eng. 2019, 7(7), 220; https://doi.org/10.3390/jmse7070220 - 15 Jul 2019
Cited by 22 | Viewed by 5753
Abstract
Nowadays, the development of new drugs only relies on a small number of molecules and 50% of all existent drugs are extracted or synthetically obtained. This work intends to evaluate the antibacterial potential of the ethanolic and polysaccharide extracts obtained from Grateloupia turuturu [...] Read more.
Nowadays, the development of new drugs only relies on a small number of molecules and 50% of all existent drugs are extracted or synthetically obtained. This work intends to evaluate the antibacterial potential of the ethanolic and polysaccharide extracts obtained from Grateloupia turuturu and to characterize the composition of the alga’s polysaccharides by FTIR-ATR. We used sequential extraction to obtain the extracts that were tested against S. aureus and E. coli. The ethanolic extracts in E. coli, at the highest concentration used (15 mg mL−1) showed 45.7% (Tetrasporophyte extract) and 55.1% (Carposporophyte extract) of growth reduction and in S. aureus 56.2% (T extract) and 51.8% (C extract). Polysaccharide extracts started showing significant reduction effect on E. coli and S. aureus growth at 7.5 mg mL−1 with a reduction of 54.9% and 39.5%, respectively. At 15 mg mL−1 the reduction observed was 88.5% and 85.4%. The FTIR-ATR allowed to characterize G. turuturu’s polysaccharides concluding that it is composed by a hybrid kappa/iota carrageenan with traces of agar, in both phases of the life cycle. This work allows us to conclude about the antibacterial properties of this alga and the compounds that might be behind this activity, showing that there’s a lot more than a small number of molecules that can be used as natural drugs. Full article
(This article belongs to the Special Issue Biotechnological Valorization of Marine Resources and By-Products)
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Review

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16 pages, 1726 KiB  
Review
The Biotechnological Potential of Secondary Metabolites from Marine Bacteria
by Boris Andryukov, Valery Mikhailov and Nataly Besednova
J. Mar. Sci. Eng. 2019, 7(6), 176; https://doi.org/10.3390/jmse7060176 - 03 Jun 2019
Cited by 44 | Viewed by 13927
Abstract
Marine habitats are a rich source of molecules of biological interest. In particular, marine bacteria attract attention with their ability to synthesize structurally diverse classes of bioactive secondary metabolites with high biotechnological potential. The last decades were marked by numerous discoveries of biomolecules [...] Read more.
Marine habitats are a rich source of molecules of biological interest. In particular, marine bacteria attract attention with their ability to synthesize structurally diverse classes of bioactive secondary metabolites with high biotechnological potential. The last decades were marked by numerous discoveries of biomolecules of bacterial symbionts, which have long been considered metabolites of marine animals. Many compounds isolated from marine bacteria are unique in their structure and biological activity. Their study has made a significant contribution to the discovery and production of new natural antimicrobial agents. Identifying the mechanisms and potential of this type of metabolite production in marine bacteria has become one of the noteworthy trends in modern biotechnology. This path has become not only one of the most promising approaches to the development of new antibiotics, but also a potential target for controlling the viability of pathogenic bacteria. Full article
(This article belongs to the Special Issue Biotechnological Valorization of Marine Resources and By-Products)
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