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Functional Composites for Bone Implants and Osseointegration
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Functional Composites for Bone Implants and Osseointegration

A special issue of Journal of Functional Biomaterials (ISSN 2079-4983). This special issue belongs to the section "Bone Biomaterials".

Deadline for manuscript submissions: 30 September 2024 | Viewed by 1292

Special Issue Editor

Dr. Sergio Olate

E-Mail Website
Guest Editor
Division of Oral and Maxillofacial Surgery, University of La Frontera, Temuco, Chile
Interests: face surgery; biomaterials; osseointegration; maxillofacial surgery; facial plastic surgery
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

The evolution and technical support for reconstructive surgery of the maxillo-mandibular complex are at a high level. Rehabilitation under the functional and aesthetic criteria are common in our practice, demonstrating adaptability in complex scenarios.

New technology of biomaterials and the recent tools for diagnosis and planning are demanded by patients, making it necessary to perform an update of these concepts. The aim of this Special Issue is to collate high-quality evidence related to bone reconstruction in the facial skeleton and osseointegration at different levels, and understand the most appropriate relevant clinical practice.

In this Special Issue, scientists and physicians are invited to share the knowledgement about biomaterials and osseointegration, through basic method and clinical research, to update on the new material in the international network supported by the journal.

Dr. Sergio Olate
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Functional Biomaterials is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • biomaterials
  • osseintegration
  • dental implants
  • reconstructive surgery
  • oral rehabilitation
  • maxillofacial surgery
  • bone graft

Published Papers (1 paper)

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Research

17 pages, 5139 KiB  
Article
Resorbable Patient-Specific Implants of Molybdenum for Pediatric Craniofacial Surgery—Proof of Concept in an In Vivo Pilot Study
by Dominik Thomas Hoppe, André Toschka, Nadia Karnatz, Henriette Louise Moellmann, Maximilian Seidl, Lutz van Meenen, Georg Poehle, Christian Redlich and Majeed Rana
J. Funct. Biomater. 2024, 15(5), 118; https://doi.org/10.3390/jfb15050118 - 29 Apr 2024
Viewed by 508
Abstract
Titanium continues to be the gold standard in the field of osteosynthesis materials. This also applies to pediatric craniofacial surgery. Various resorbable materials have already been developed in order to avoid costly and risky second operations to remove metal in children. However, none [...] Read more.
Titanium continues to be the gold standard in the field of osteosynthesis materials. This also applies to pediatric craniofacial surgery. Various resorbable materials have already been developed in order to avoid costly and risky second operations to remove metal in children. However, none of these resorbable materials have been able to completely replace the previous gold standard, titanium, in a satisfactory manner. This has led to the need for a new resorbable osteosynthesis material that fulfills the requirements for biocompatibility, stability, and uniform resorption. In our previous in vitro and in vivo work, we were able to show that molybdenum fulfills these requirements. To further confirm these results, we conducted a proof of concept in four domestic pigs, each of which was implanted with a resorbable molybdenum implant. The animals were then examined daily for local inflammatory parameters. After 54 days, the animals were euthanized with subsequent computer tomography imaging. We also removed the implants together with the surrounding tissue and parts of the spleen, liver, and kidney for histopathological evaluation. The molybdenum implants were also analyzed metallographically and using scanning electron microscopy. A blood sample was taken pre- and post-operatively. None of the animals showed clinical signs of inflammation over the entire test period. Histopathologically, good tissue compatibility was found. Early signs of degradation were observed after 54 days, which were not sufficient for major resorption. Resorption is expected with longer in situ residence times based on results of similar earlier investigations. Full article
(This article belongs to the Special Issue Functional Composites for Bone Implants and Osseointegration)
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