Advances in Functional Biomaterials Fabricated by Powder Metallurgy Approaches

A special issue of Journal of Functional Biomaterials (ISSN 2079-4983). This special issue belongs to the section "Synthesis of Biomaterials via Advanced Technologies".

Deadline for manuscript submissions: closed (31 December 2023) | Viewed by 3460

Special Issue Editors


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Guest Editor
Center of Functional Nano-Ceramics, National University of Science and Technology “MISiS”, Leninskiy Prospekt 4, 119049 Moscow, Russia
Interests: powder metallurgy; biomaterials for medical devices; field-assisted sintering technology; spark plasma sintering; additive manufacturing; nanocomposites

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Guest Editor
1. Center of Functional Nano-Ceramics, National University of Science and Technology “MISiS”, Leninskiy Prospekt 4, 119049 Moscow, Russia
2. Research Laboratory of Scanning Probe Microscopy, Moscow Polytechnic University, B. Semenovskaya St. 38, 107023 Moscow, Russia
Interests: combustion synthesis; advanced materials; functional biomaterials; ceramic materials; spark plasma sintering
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Special Issue Information

Dear Colleagues,

Powder metallurgy (PM) has been used in the manufacturing of functional biomaterials for decades. PM is cost-effective, efficient, and often produces superior products relative to other manufacturing processes. PM involves the process of blending, forming, compacting, and sintering biocompatible materials into a cohesive and desired product. By controlling the geometry, size, and distribution of elements within the particulate components, biomaterials can be designed to be highly tailored to desired functional requirements. Furthermore, sophisticated fabrications can be realized when producing complex biomaterial components. PM-manufactured biomaterials have been used in various applications, such as the production of hip, knee, and dental implants, as well as stents, vascular grafts, and heart valves. These components require strength, durability, and biocompatibility, all of which can be met by PM-manufactured components. Moreover, due to the current renaissance in employing lighter and lower cost medical devices in healthcare settings, PM offers ideal solutions.

Recently, advanced fabrication parameters have been employed to improve the performance of PM-manufactured implants. Various advanced techniques, such as additive manufacturing (AM), spark plasma sintering (SPS), flash sintering (FS), microwave sintering (MS), hot isostatic pressing (HIP), cold isostatic pressing (CIP), metal injection molding (MIM), and so on, are being used alongside traditional PM processes to fabricate high-quality implants. These techniques offer the potential to create 3D implant architectures with tailored densities and complex geometries—additional features that could be beneficial to the medical community. Overall, PM plays an important role in the development of functional biomaterials, and further advances in PM can produce even more advanced products and components for a variety of applications.

This Special Issue of “Advances in Functional Biomaterials Fabricated by Powder Metallurgy Approaches” focuses on the use of PM techniques to create materials suitable for medical implants and devices. It covers a wide range of topics related to the use of PM approaches in the synthesis and processing of biomaterials, as well as their characterization and application in medical devices. The articles in the issue highlight the potential of PM to produce biomedical implants, develop new materials for bone regeneration, and improve the performance of medical devices. It provides a comprehensive overview of the latest advances in the field, including research articles, reviews, and perspectives. Overall, this Special Issue is an important resource for researchers, engineers, and medical professionals who are interested in the development of new biomaterials via PM manufacturing techniques that can improve the performance and functionality of medical implants and devices. Furthermore, the issue contains articles discussing the mechanical, chemical, and physical properties; electrochemical tests; and wear behavior of materials fabricated by powder metallurgy. The articles cover a variety of material systems and show potential for expanding the use of PM for medical and healthcare applications. The information presented provides a comprehensive overview of the variety of materials produced via PM, the challenges in production, and the potential for their successful application.

Dr. Mohammad Abedi
Dr. Dmitry Moskovskikh
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Functional Biomaterials is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • functional biomaterials
  • biodegradable materials
  • powder metallurgy
  • powder synthesis
  • powder injection molding
  • conventional sintering
  • field-assisted sintering technology
  • spark plasma sintering
  • additive manufacturing

Published Papers (2 papers)

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Research

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14 pages, 3029 KiB  
Article
Fabrication of Biomedical Ti-Zr-Nb by Reducing Metal Oxides with Calcium Hydride
by Sergey Yudin, Ivan Alimov, Sergey Volodko, Alexander Gurianov, Galina Markova, Anatoly Kasimtsev, Tatiana Sviridova, Darya Permyakova, Evgeny Evstratov, Vladimir Cheverikin and Dmitry Moskovskikh
J. Funct. Biomater. 2023, 14(5), 271; https://doi.org/10.3390/jfb14050271 - 13 May 2023
Cited by 1 | Viewed by 1246
Abstract
In the present study, a powder of Ti-18Zr-15Nb biomedical alloy with spongy morphology and with more than 95% vol. of β-Ti was obtained by reducing the constituent oxides with calcium hydride. The influence of the synthesis temperature, the exposure time, and the density [...] Read more.
In the present study, a powder of Ti-18Zr-15Nb biomedical alloy with spongy morphology and with more than 95% vol. of β-Ti was obtained by reducing the constituent oxides with calcium hydride. The influence of the synthesis temperature, the exposure time, and the density of the charge (TiO2 + ZrO2 + Nb2O5 + CaH2) on the mechanism and kinetics of the calcium hydride synthesis of the Ti-18Zr-15Nb β-alloy was studied. Temperature and exposure time were established as crucial parameters with the help of regression analysis. Moreover, the correlation between the homogeneity of the powder obtained and the lattice microstrain of β-Ti is shown. As a result, temperatures above 1200 °C and an exposure time longer than 12 h are required to obtain a Ti-18Zr-15Nb powder with a single β-phase structure and uniformly distributed elements. The analysis of β-phase growth kinetics revealed that the formation of β-Ti occurs due to the solid-state diffusion interaction between Ti, Nb, and Zr under the calcium hydride reduction of TiO2 + ZrO2 + Nb2O5, and the spongy morphology of reduced α-Ti is inherited by the β-phase. Thus, the results obtained provide a promising approach for manufacturing biocompatible porous implants from β-Ti alloys that are believed to be attractive candidates for biomedical applications. Moreover, the current study develops and deepens the theory and practical aspects of the metallothermic synthesis of metallic materials and can be compelling to specialists in powder metallurgy. Full article
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33 pages, 4643 KiB  
Review
Selective Laser Melting and Spark Plasma Sintering: A Perspective on Functional Biomaterials
by Ramin Rahmani, Sérgio Ivan Lopes and Konda Gokuldoss Prashanth
J. Funct. Biomater. 2023, 14(10), 521; https://doi.org/10.3390/jfb14100521 - 16 Oct 2023
Cited by 5 | Viewed by 1875
Abstract
Achieving lightweight, high-strength, and biocompatible composites is a crucial objective in the field of tissue engineering. Intricate porous metallic structures, such as lattices, scaffolds, or triply periodic minimal surfaces (TPMSs), created via the selective laser melting (SLM) technique, are utilized as load-bearing matrices [...] Read more.
Achieving lightweight, high-strength, and biocompatible composites is a crucial objective in the field of tissue engineering. Intricate porous metallic structures, such as lattices, scaffolds, or triply periodic minimal surfaces (TPMSs), created via the selective laser melting (SLM) technique, are utilized as load-bearing matrices for filled ceramics. The primary metal alloys in this category are titanium-based Ti6Al4V and iron-based 316L, which can have either a uniform cell or a gradient structure. Well-known ceramics used in biomaterial applications include titanium dioxide (TiO2), zirconium dioxide (ZrO2), aluminum oxide (Al2O3), hydroxyapatite (HA), wollastonite (W), and tricalcium phosphate (TCP). To fill the structures fabricated by SLM, an appropriate ceramic is employed through the spark plasma sintering (SPS) method, making them suitable for in vitro or in vivo applications following minor post-processing. The combined SLM-SPS approach offers advantages, such as rapid design and prototyping, as well as assured densification and consolidation, although challenges persist in terms of large-scale structure and molding design. The individual or combined application of SLM and SPS processes can be implemented based on the specific requirements for fabricated sample size, shape complexity, densification, and mass productivity. This flexibility is a notable advantage offered by the combined processes of SLM and SPS. The present article provides an overview of metal–ceramic composites produced through SLM-SPS techniques. Mg-W-HA demonstrates promise for load-bearing biomedical applications, while Cu-TiO2-Ag exhibits potential for virucidal activities. Moreover, a functionally graded lattice (FGL) structure, either in radial or longitudinal directions, offers enhanced advantages by allowing adjustability and control over porosity, roughness, strength, and material proportions within the composite. Full article
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