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Topical Collection "Advances in Understanding the Pathogenesis and Pathophysiology of Orthopaedic-Related Infections"
A topical collection in Journal of Clinical Medicine (ISSN 2077-0383). This collection belongs to the section "Orthopedics".Viewed by 15664
Interests: periprosthetic joint infection; osteolysis; osteoarthritis; osteoporosis; osteocyte; bone remodelling
Special Issues, Collections and Topics in MDPI journals
Topical Collection Information
Osteomyelitis related to orthopaedic interventions and peripheral vascular disease represent a serious health and healthcare burden. Individuals who are obese, diabetic, chronic smokers, immunocompromised, or have undergone dental surgery are at increased risk of developing periprosthetic joint infection (PJI). Patients being treated for bone and joint reconstruction surgery following cancer treatment have a greatly elevated risk of developing a PJI. Individuals who have suffered trauma, in particular, open fractures, are at high risk of developing a fracture-related infection (FRI). These conditions involve infection of surgical implants and of the surrounding soft and hard tissues. Patients with peripheral vascular disease, such as those with diabetes mellitus, are at increased risk of developing a foot ulcer that will develop into a localised osteomyelitis, termed diabetic foot infection (DFI). All of these infection types are contributed to by both host- and pathogen-derived factors, and all are associated with a high incidence of recurrent or chronic disease. In this Special Issue, we seek to explore advances in our understanding of the pathogenesis, pathophysiology, and treatment of these related disease types.
Prof. Dr. Gerald Atkins
Manuscript Submission Information
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- orthopaedic infection
- periprosthetic joint infection
- fracture-related infection
- diabetic foot infection
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