Clinical Management of Acute Respiratory Distress Syndrome

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Pulmonology".

Deadline for manuscript submissions: 25 August 2024 | Viewed by 93

Special Issue Editor

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Guest Editor
Department of Anesthesia and Intensive Care, ASST Santi Paolo e Carlo, San Paolo University Hospital, 20142 Milan, Italy
Interests: adult respiratory distress syndrome; ARDS; artificial ventilation; lung injury; critical care; respiratory failure

Special Issue Information

Dear Colleagues,

Adult respiratory distress syndrome (ARDS) is a severe and life-threatening condition characterized by acute lung injury leading to non-cardiogenic pulmonary edema and respiratory failure.  ARDS typically occurs due to direct or indirect injury to the lung parenchyma, leading to increased permeability of the alveolar–capillary membrane and subsequent accumulation of protein-rich fluid in the alveoli. This impairment of gas exchange results in severe hypoxemia and respiratory distress. The clinical presentation often includes an acute onset of dyspnea, hypoxemia, tachypnea, and diffuse bilateral infiltrates on chest imaging.

The management of ARDS involves a comprehensive approach aimed at optimizing oxygenation, reducing ventilator-induced lung injury, and treating the underlying cause. Strategies include mechanical ventilation with a low tidal volume and positive end-expiratory pressure to minimize barotrauma and volutrauma, prone positioning to improve oxygenation, and fluid management to avoid excessive fluid administration.

In conclusion, ARDS is a complex syndrome associated with high morbidity and mortality. Early recognition, timely intervention, and appropriate management are crucial in improving clinical outcomes. The understanding of ARDS pathogenesis and tailored treatment strategies has evolved over the years, helping improve survival rates and promote better patient care. The purpose of this abstract is to provide an overview of ARDS, discussing its clinical presentation, diagnostic criteria, and management strategies.

We look forward to receiving your submissions to this Special Issue.

Dr. Silvia Coppola
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • adult respiratory distress syndrome
  • ARDS
  • acute lung injury
  • non-cardiogenic pulmonary edema
  • hypoxemia
  • mechanical ventilation
  • positive end-expiratory pressure
  • respiratory failure

Published Papers

This special issue is now open for submission.
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