Clinical Diagnosis and Rehabilitation of Pulmonary Hypertension and Pulmonary Embolism

Dear Colleagues,

Pulmonary hypertension (PH) is a hemodynamic condition characterized by an increase in pressure in the pulmonary artery secondary to various pathological conditions. Accurate diagnosis and the correct clinical framing of PH are prerequisites for adequate treatment able to improve not only the symptoms and quality of life but also the survival rates of patients. The management of PH may include targeted pharmacotherapy, sophisticated percutaneous interventions, or surgery, as well as various combination and hybrid approaches. In patients with PH who are medically stable, supervised exercise-based rehabilitation may result in a large increase in exercise capacity and improve quality of life. However, despite the progress that we are witnessing, challenges remain in the application of exercise-based rehabilitation across the spectrum of people with PH, including those with chronic thromboembolic PH, PH with left-sided heart disease, and those with more severe disease, and even more are emerging.

Acute pulmonary embolism (PE) is caused by the abrupt occlusion of pulmonary arteries from a thrombus formed in the venous system. PE is one of the most frequent acute cardiovascular syndromes, and its incidence continues to rise worldwide. Along with symptoms of dyspnea and chest pain, if there is a significant thrombus burden, right ventricular strain can result in the potential for cardio-pulmonary collapse. Besides the risk of death, venous thromboembolism recurrence, the occurrence of the post-PE syndrome, and PE-related quality of life/functional status are further outcomes that matter to patients with PE. Although the current sophisticated diagnosis and management of PE have considerably improved the prognosis of patients with PE, they remain at risk of developing long-term sequela such as post-PE syndrome. Pulmonary rehabilitation is of great value for these patients since it can improve recovery and prognosis.

Studies on the recent advances in PH and PE diagnosis and management are welcome for this Special Issue. We are also inviting researchers, physicians, and clinical scientists to submit their manuscripts with the goal of advancing the knowledge and understanding where we currently stand on rehabilitation in the PH and PE.

We look forward to your contributions!

Dr. Sylwia Sławek-Szmyt
Dr. Aleksander Araszkiewicz
Guest Editors

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• pulmonary hypertension
• pulmonary embolism
• rehabilitation
• diagnosis
• post-PE syndrome
• quality of life