Sjogren's Syndrome: Complications and Treatment
A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Immunology".
Deadline for manuscript submissions: 30 September 2024 | Viewed by 89
Special Issue Editors
Interests: sjogren’s syndrome; psoriatic arthritis; ultrasonography; rheumatoid arthritis; gout; ostheoarthritis
Special Issues, Collections and Topics in MDPI journals
Interests: psoriatic arthritis; psoriasis; rheumatoid arthritis; ultrasonography
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Primary Sjögren’s syndrome (pSS) is an autoimmune systemic disease characterized by the destruction of exocrine glands. The lack of saliva and persistent ocular dryness result in increased susceptibility to teeth cavities and corneal damage.
Beyond the dryness discomfort, the systemic nature of pSS implies its potential to impact diverse organs, including the lungs, kidneys, nervous system, and musculoskeletal system. Lymphoma is the most fearable and severe complication, usually localized in the major salivary gland. Parotid swelling is a major predictor of lymphoproliferative disease; therefore, ultrasonographic assessment may provide an early diagnosis, leading to a focused biopsy, contributing to an early diagnosis. Given the wide spectrum of clinical manifestations and complications, disease diagnosis can often be challenging.
From a therapeutic standpoint, there are strategies to alleviate symptoms. At present, local moisturizing treatment can provide relief for dry eyes and mouth, whereas immunosuppressive medications may be prescribed to manage the autoimmune response and reduce inflammation; however, no specific treatment for pSS is currently available.
Considering these challenges, we encourage researchers to submit original research articles and reviews focusing on the early diagnosis of the disease and its complications. Additionally, contributions related to novel immunomodulatory therapeutic interventions and symptom relief are welcome for submission.
Dr. Ivan Giovannini
Dr. Alen Zabotti
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- lymphoma
- ultrasonography
- core needle biopsy
- immunosuppressive treatment
- parotid swelling
