Targeted Diagnosis and Treatment of Atrial Fibrillation

Dear Colleagues,

This Special Issue delves into three pivotal aspects shaping the landscape of modern cardiology, particularly in the realm of atrial fibrillation (AF). It builds upon the growing body of evidence suggesting that autonomic dysfunction contributes to AF development and progression. Additionally, there have been exciting developments in diagnostic tools for AF screening and subclinical AF detection; thus, their impact on AF patient management needs to be determined. Finally, recent advances and novel modalities in AF ablation technology—according to different clinical setting—may enable better ablation outcomes.

Specifically, the primary focus of this Special Issue revolves around the intricate interplay of the autonomic nervous system in AF, shedding light on its nuanced role in the initiation, perpetuation and progression of this common arrhythmia. The intricate connections between autonomic dysregulation and AF provide a deeper understanding of potential therapeutic targets and avenues for intervention.

In addition to exploring the autonomic nervous system, this issue highlights AF screening and subclinical detection. Recognizing the significance of early identification, this issue aims to explore technological advancements in detecting signs of AF that may precede clinical manifestations. An emphasis is placed on novel screening methods, diagnostic tools and their potential impact on preventive strategies, use of anticoagulation and patient outcomes.

Furthermore, this issue extends its scope to the latest breakthroughs in energy sources for AF ablation. Cutting-edge technologies and emerging modalities, including, but not limited to, pulsed field are elucidated, presenting novel approaches that hold promise for improved efficacy and reduced procedural complications in AF ablation. This section aims to provide clinicians and researchers with a nuanced understanding of the evolving landscape of AF ablation techniques.

By synthesizing these three key areas—autonomic nervous system involvement in AF, subclinical AF detection and innovative energy sources for AF ablation—this issue seeks to offer a comprehensive overview of the current state of research and clinical perspectives.

Dr. Dimitris L. Tsiachris
Dr. Stavros Stavrakis
Guest Editors

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• atrial fibrillation
• atrial cardiopathy
• autonomic nervous system
• pulsed field ablation
• smart watches
• antiarrhythmic drugs