International Journal of Environmental Research and Public Health

Research

Jump to: Other

12 pages, 2287 KiB

Open AccessArticle

Guided Tissue Regeneration Treatment Yields Better Results in Class II Furcations in the Mandible Than in the Maxilla: A Retrospective Study

by Odontuya Dorj, Wei-Fang Lee, Eisner Salamanca, Yu-Hwa Pan, Yi-Fan Wu, Yung-Szu Hsu, Jerry C. Y. Lin, Yu-De Lin, Cheuk-Sing Choy and Wei-Jen Chang

Int. J. Environ. Res. Public Health 2021, 18(14), 7447; https://doi.org/10.3390/ijerph18147447 - 13 Jul 2021

Cited by 4 | Viewed by 3064

Abstract

Absorbable porcine collagen membrane with a bovine bone graft can be considered for regenerative treatment in periodontal class II furcation defects. We evaluated the clinical efficacy of guided tissue regeneration (GTR) treatment with bovine bone xenograft and a porcine collagen membrane in molars [...] Read more.

Absorbable porcine collagen membrane with a bovine bone graft can be considered for regenerative treatment in periodontal class II furcation defects. We evaluated the clinical efficacy of guided tissue regeneration (GTR) treatment with bovine bone xenograft and a porcine collagen membrane in molars with class II furcations. Probing depth (PD), clinical attachment level (CAL), and bone level (BL) were recorded at baseline and at 3, 6, and 9 months postoperatively. Thirty class II furcation defects from the lower and upper molars were assessed. Significant improvements in PD and CAL were observed from baseline to 9 months in all groups (p < 0.01). BL improved in all groups except group A in the upper molars in radiographic assessment (p < 0.05). The lower and upper molars showed PD reduction of 50.5% ± 7.44% and 46.2% ± 11.2%, respectively, at 9 months (p = 0.044). In furcations of 1–3 mm, the lower and upper molars showed PD reductions of 51.2% ± 4.49% and 36.5% ± 16.14%, respectively (p = 0.035). The lower and upper molars showed a CAL gain of 51.1% ± 4.64% and 33.6% ± 18.8%, respectively (p = 0.037). Thus, GTR with bovine bone graft and porcine collagen membrane yielded good results in class II furcations, with better results in the lower than in the upper molars. Full article

(This article belongs to the Special Issue Oral Health and Host Related Environmental Factors in Periodontal Status)

► Show Figures

Figure 1

10 pages, 651 KiB

Open AccessArticle

Increased Risk of Migraine in Patients with Chronic Periodontitis: A Population-Based Cohort Study

by Yung-Kai Huang, Li-Chiu Yang, Yu-Hsun Wang and Yu-Chao Chang

Int. J. Environ. Res. Public Health 2021, 18(4), 1921; https://doi.org/10.3390/ijerph18041921 - 17 Feb 2021

Cited by 6 | Viewed by 3092

Abstract

Migraine is considered to be a neurovascular disease that manifests as a throbbing headache, possibly caused by the activation of the trigeminovascular system. Several studies have supported the role of inflammation in the pathogenesis of migraine. Chronic periodontitis (CP) is an infectious inflammatory [...] Read more.

Migraine is considered to be a neurovascular disease that manifests as a throbbing headache, possibly caused by the activation of the trigeminovascular system. Several studies have supported the role of inflammation in the pathogenesis of migraine. Chronic periodontitis (CP) is an infectious inflammatory disease triggered by bacterial products evoking an immune response which could result in the destruction of the periodontium. However, little is known about the longitudinal association between CP and migraine. In this study, we designed a nationwide population-based cohort study to investigate the risk of migraine and CP exposure in Taiwan. In total, 68,282 patients with CP were identified from the National Health Insurance Research Database (NHIRD), and 68,282 comparisons were randomly captured and matched by age, sex, monthly income, urbanization and comorbidities. The association between CP exposure and migraine risk was evaluated by Cox proportional hazards regression models. In this study, 785 migraine patients were identified in the CP cohort, and 641 migraine cases were found in the non-CP cohort. The incidence rate of migraine was significantly higher in the CP cohort than the non-CP cohort (adjusted HR: 1.21, 95% CI: 1.09–1.34, p < 0.001) during the 13-year follow-up period. Females had a 2.69-fold higher risk for migraine than males (95% CI: 2.38–3.04, p < 0.001). In summary, CP is associated with an increased risk of subsequent migraine in Taiwan. Full article

(This article belongs to the Special Issue Oral Health and Host Related Environmental Factors in Periodontal Status)

► Show Figures

Figure 1

8 pages, 1224 KiB

Open AccessArticle

Chronic Periodontitis Is Associated with the Risk of Bipolar Disorder: A Population-Based Cohort Study

by Yung-Kai Huang, Yu-Hsun Wang and Yu-Chao Chang

Int. J. Environ. Res. Public Health 2020, 17(10), 3466; https://doi.org/10.3390/ijerph17103466 - 15 May 2020

Cited by 8 | Viewed by 2183

Abstract

Bipolar disorder (BD) is a psychiatric mood disturbance manifested by manic, hypomanic, or major depressive periods. Chronic inflammation was evidenced as an important etiologic factor of BD. Chronic periodontitis (CP) is an inflammatory disease triggered by bacterial products, leading to the destruction of [...] Read more.

Bipolar disorder (BD) is a psychiatric mood disturbance manifested by manic, hypomanic, or major depressive periods. Chronic inflammation was evidenced as an important etiologic factor of BD. Chronic periodontitis (CP) is an inflammatory disease triggered by bacterial products, leading to the destruction of periodontium. The relationship between BD and CP is of interest to investigate. Therefore, a nationwide population-based cohort study was used to investigate the risk of BD and CP exposure from 2001 to 2012. We identified 61,608 patients with CP from the Taiwanese National Health Insurance Research Database (NHIRD). The 123,216 controls were randomly captured and matched by age, sex, index year, and co-morbidities. The association between CP exposure and BD risk was examined by Cox proportional hazards regression models. In this study, 61,608 CP patients and 123,216 controls were followed up for 7.45 and 7.36 years, respectively. In total, 138 BD patients were identified in the CP cohort and 187 BD cases were found in the non-CP cohort. The incidence rate of BD was significantly higher in the CP cohort than in the non-CP cohort (adjusted HR: 1.46, 95% CI: 1.17–1.81) according to the multivariate Cox regression analysis. Females had a 1.47-fold increased risk (95% CI: 1.16–1.86) for BD compared to males. Taken together, CP may be associated with an increased risk of subsequent BD in Taiwan. Full article

(This article belongs to the Special Issue Oral Health and Host Related Environmental Factors in Periodontal Status)

► Show Figures

Figure 1

8 pages, 831 KiB

Open AccessArticle

Variation in the Occurrence of fimA Genotypes of Porphyromonas gingivalis in Periodontal Health and Disease

by Manohar Kugaji, Uday Muddapur, Kishore Bhat, Vinayak Joshi, Manjunath Manubolu, Kavitha Pathakoti, Malleswara Rao Peram and Vijay Kumbar

Int. J. Environ. Res. Public Health 2020, 17(6), 1826; https://doi.org/10.3390/ijerph17061826 - 11 Mar 2020

Cited by 6 | Viewed by 2480

Abstract

Porphyromonas gingivalis is regarded as a “keystone pathogen” in periodontitis. The fimbria assists in the initial attachment, biofilm organization, and bacterial adhesion leading to the invasion and colonization of host epithelial cells. The present study aimed to investigate the occurrence of fimA genotypes [...] Read more.

Porphyromonas gingivalis is regarded as a “keystone pathogen” in periodontitis. The fimbria assists in the initial attachment, biofilm organization, and bacterial adhesion leading to the invasion and colonization of host epithelial cells. The present study aimed to investigate the occurrence of fimA genotypes in patients with chronic periodontitis and healthy individuals in the Indian population, and to study their association with the number of P. gingivalis cells obtained in subgingival plaque samples of these subjects. The study comprised 95 samples from the chronic periodontitis (CP) group and 35 samples from the healthy (H) group, which were detected positive for P. gingivalis in our previous study. Fimbrial genotyping was done by PCR and PCR-restriction fragment length polymorphism (RFLP). The fimA type II was more prevalent in the CP group (55.89%), followed by type IV (30.52%), whereas in the H group, type I was the most prevalent fimbria (51.42%). The quantity of P. gingivalis cells increased with the presence of fimA types II and III. Our results suggest a strong relationship between fimA types II and IV and periodontitis, and between type I and the healthy condition. The colonization of organisms was increased with the occurrence of type II in deep periodontal sites, which could play an important role in the progression of the disease. Full article

(This article belongs to the Special Issue Oral Health and Host Related Environmental Factors in Periodontal Status)

► Show Figures

Figure 1

10 pages, 981 KiB

Open AccessArticle

The Association of Periodontal Treatment and Decreased Pneumonia: A Nationwide Population-Based Cohort Study

by Li-Chiu Yang, Yih-Jane Suen, Yu-Hsun Wang, Tai-Chen Lin, Hui-Chieh Yu and Yu-Chao Chang

Int. J. Environ. Res. Public Health 2020, 17(1), 356; https://doi.org/10.3390/ijerph17010356 - 05 Jan 2020

Cited by 30 | Viewed by 4948

Abstract

Pneumonia is a common respiratory infectious disease that involves the inflammation of the pulmonary parenchyma. Periodontal disease is widespread and correlated with pneumonia. However, the relationship between periodontal treatment and clinical infectious outcomes in patients with pneumonia has remained undetermined. The aim of [...] Read more.

Pneumonia is a common respiratory infectious disease that involves the inflammation of the pulmonary parenchyma. Periodontal disease is widespread and correlated with pneumonia. However, the relationship between periodontal treatment and clinical infectious outcomes in patients with pneumonia has remained undetermined. The aim of this study was to investigate the association between periodontal treatment and the risk of pneumonia events in the Taiwanese population. A nationwide population-based cohort study was conducted using data from the Taiwanese National Health Insurance Research Database (NHIRD). A total of 49,400 chronic periodontitis patients who received periodontal treatment from 2001 to 2012 were selected. In addition, 49,400 healthy individuals without periodontal diseases were picked randomly from the general population after propensity score matching according to age, gender, monthly income, urbanization, and comorbidities. The Cox proportional hazard regression analysis was adopted to assess the hazard ratio (HR) of pneumonia between the periodontal treatment cohort and the comparison cohort. The average ages of the periodontal treatment and comparison groups were 44.25 ± 14.82 years and 44.15 ± 14.5 years, respectively. The follow up durations were 7.66 and 7.41 years for the periodontal treatment and comparison groups, respectively. We found 2504 and 1922 patients with newly diagnosed pneumonia in the comparison cohort and the periodontal treatment cohort, respectively. The Kaplan–Meier plot revealed that the cumulative incidence of pneumonia was significantly lower over the 12 year follow-up period in the periodontal treatment group (using the log-rank test, p < 0.001). In conclusion, this nationwide population-based study indicated that the patients with periodontal treatment exhibited a significantly lower risk of pneumonia than the general population. Full article

(This article belongs to the Special Issue Oral Health and Host Related Environmental Factors in Periodontal Status)

► Show Figures

Figure 1

11 pages, 1760 KiB

Open AccessArticle

Prevention of Bone Resorption by HA/β-TCP + Collagen Composite after Tooth Extraction: A Case Series

by Hsi Kuei Lin, Yu Hwa Pan, Eisner Salamanca, Yu Te Lin and Wei Jen Chang

Int. J. Environ. Res. Public Health 2019, 16(23), 4616; https://doi.org/10.3390/ijerph16234616 - 21 Nov 2019

Cited by 22 | Viewed by 3957

Abstract

After tooth extraction, alveolar ridge loss due to resorption is almost inevitable. Most of this bone loss occurs during the first six months after the extraction procedure. Many studies have indicated that applying socket-filling biomaterials after extraction can effectively reduce the resorption rate [...] Read more.

After tooth extraction, alveolar ridge loss due to resorption is almost inevitable. Most of this bone loss occurs during the first six months after the extraction procedure. Many studies have indicated that applying socket-filling biomaterials after extraction can effectively reduce the resorption rate of the alveolar ridge. The purpose of this study was to investigate the clinical efficacy of the application of a hydroxyapatite/β-tricalcium plus collagen (HA/β-TCP + collagen) dental bone graft in dental sockets immediately after tooth extraction, so as to prevent socket resorption. The study was conducted on 57 extraction sockets located in the mandible and maxilla posterior regions in 51 patients. HA/β-TCP + collagen was inserted into all of the dental sockets immediately after extraction, and was covered with a flap. Follow-up was performed for three months after extraction, using radiographs and stents for the vertical and horizontal alveolar ridge measurements. A minimal alveolar bone width reduction of 1.03 ± 2.43 mm (p < 0.05) was observed. The height reduction showed a slight decrease to 0.62 ± 1.46 mm (p < 0.05). Radiographically, the bone height was maintained after three months, indicating a good HA/β-TCP + collagen graft performance in preserving alveolar bone. In conclusion, the HA/β-TCP + collagen graft demonstrated adequate safety and efficacy in dental socket preservation following tooth extraction. Full article

(This article belongs to the Special Issue Oral Health and Host Related Environmental Factors in Periodontal Status)

► Show Figures

Figure 1

13 pages, 417 KiB

Open AccessArticle

Periodontal Treatment Experience Associated with Oral Health-Related Quality of Life in Patients with Poor Glycemic Control in Type 2 Diabetes: A Case-Control Study

by Yuan-Jung Hsu, Kun-Der Lin, Jen-Hao Chen, Mei-Yueh Lee, Ying-Chu Lin, Feng-Chieh Yen and Hsiao-Ling Huang

Int. J. Environ. Res. Public Health 2019, 16(20), 4011; https://doi.org/10.3390/ijerph16204011 - 19 Oct 2019

Cited by 10 | Viewed by 3600

Abstract

Severe periodontitis is a risk factor for poor glycemic control. The appropriate medical treatment and plaque control of periodontitis positively affects blood-sugar control in diabetes patients. We aimed to identify the factors associated with glycemic control and examine the periodontal treatment (PT) experience [...] Read more.

Severe periodontitis is a risk factor for poor glycemic control. The appropriate medical treatment and plaque control of periodontitis positively affects blood-sugar control in diabetes patients. We aimed to identify the factors associated with glycemic control and examine the periodontal treatment (PT) experience and oral health-related quality of life (OHQoL) for patients with poor glycemic control in type 2 diabetes mellitus (T2DM). This multicenter case–control study recruited 242 patients with poor glycemic control and 198 patients with good glycemic control. We collected patients’ information through face-to-face interviews using a structured questionnaire. The Oral Health Impact Profile-14 (OHIP-14) was used to measure OHQoL. Based on PT status, the patients were classified into three groups: a non-periodontal disease group, a PT group, and a non-PT (NPT) group. Regression models were used to analyze the data. No interdental cleaning (adjusted odds ratio (aOR) = 1.78) and positive attitudes toward periodontal health (aOR = 1.11) were significantly more likely to be associated with poor glycemic control in patients with T2DM. The PT group had a significantly lower OHIP-14 score than the NPT group (6.05 vs. 9.02, p < 0.001), indicating a better OHQoL among patients with poorly controlled T2DM. However, the OHQoL did not differ significantly in patients with well-controlled T2DM between the PT and NPT groups. This suggested that diabetic patients with poor glycemic control must improve periodontal care practices and receive proper PT, if necessary, to improve their OHQoL. Full article

(This article belongs to the Special Issue Oral Health and Host Related Environmental Factors in Periodontal Status)

► Show Figures

Figure 1

14 pages, 682 KiB

Open AccessArticle

Randomized Controlled Trial on Effects of a Brief Clinical-Based Intervention Involving Planning Strategy on Self-Care Behaviors in Periodontal Patients in Dental Practice

by Jo-Hsin Lin, Yuan-Kai Huang, Kun-Der Lin, Yuan-Jung Hsu, Wei-Fu Huang and Hsiao-Ling Huang

Int. J. Environ. Res. Public Health 2019, 16(20), 3838; https://doi.org/10.3390/ijerph16203838 - 11 Oct 2019

Cited by 5 | Viewed by 2744

Abstract

Background: Strengthening adherence to self-care behaviors in patients with periodontal disease (PD) and reducing the plaque index is crucial for improving PD treatment. We evaluated the effectiveness of a theory of planned behavior (TPB)-based health education intervention involving a planning strategy on self-care [...] Read more.

Background: Strengthening adherence to self-care behaviors in patients with periodontal disease (PD) and reducing the plaque index is crucial for improving PD treatment. We evaluated the effectiveness of a theory of planned behavior (TPB)-based health education intervention involving a planning strategy on self-care behaviors in patients with PD. Methods: A randomized controlled trial was conducted; 158 and 139 patients comprised the experimental group (EG) and control group (CG), respectively. Both groups received a leaflet, and the EG also received a planning intervention, which was a brief one-on-one counseling session with a planning sheet. Data were collected using a self-administered questionnaire. Results: Between-group comparisons of TPB measures revealed significant differences in all domains when controlling for baseline covariates. The EG exhibited significantly higher levels of action and coping planning than the CG at two-week follow-up (effect size (ES) = 5.54 and 5.57, respectively) and six-week follow-up (ES = 5.66 and 5.66, respectively). Between-group differences in changes of brushing behaviors increased significantly. More frequent use of dental floss was observed in the EG than in the CG at two-week and six-week follow-ups (24.7% and 22.8%, respectively). Conclusions: The intervention involving planning strategy effectively promoted adherence to self-care behaviors in patients with PD. Full article

(This article belongs to the Special Issue Oral Health and Host Related Environmental Factors in Periodontal Status)

► Show Figures

Figure 1

12 pages, 2698 KiB

Open AccessArticle

Evaluation of the Peri-Implant Bone Level around Platform-Switched Dental Implants: A Retrospective 3-Year Radiographic Study

by Yu Hwa Pan, His Kuei Lin, Jerry C-Y Lin, Yung-Szu Hsu, Yi-Fan Wu, Eisner Salamanca and Wei-Jen Chang

Int. J. Environ. Res. Public Health 2019, 16(14), 2570; https://doi.org/10.3390/ijerph16142570 - 18 Jul 2019

Cited by 20 | Viewed by 7518

Abstract

Objective: To describe remodeling of the mesial and distal marginal bone level around platform-switched (PS) and platform-matched (PM) dental implants that were sandblasted with large grit and etched with acid over a three-year period. Materials and Methods: Digital periapical radiographs were obtained at [...] Read more.

Objective: To describe remodeling of the mesial and distal marginal bone level around platform-switched (PS) and platform-matched (PM) dental implants that were sandblasted with large grit and etched with acid over a three-year period. Materials and Methods: Digital periapical radiographs were obtained at the following time-points: during Stage I of the surgical placement of dental implants, before loading, immediately after loading (baseline), and one, three, six, 12, and 36 months after loading for measuring the horizontal and vertical marginal bone levels. Results: Sixty implants were successfully osseointegrated during the overall observation period. Vertical marginal bone levels for the PS and PM dental implants were 0.78 ± 0.77 and 0.98 ± 0.81 mm, respectively, whereas the horizontal marginal bone levels for the PS and PM implants were 0.84 ± 0.45 and 0.98 ± 0.68 mm, respectively. During the time leading up to the procedure until 36 months after the procedure, the average vertical marginal bone level resulted in less bone loss for the PS and PM groups—0.96 ± 1.28 and 0.30 ± 1.15 mm, respectively (p < 0.05). The mean levels of the horizontal marginal bone also showed increases of 0.48 ± 1.01 mm in the PS and 0.37 ± 0.77 mm in the PM groups from the time before loading until 36 months after the procedure. However, these increases were not statistically significant (p > 0.05). Conclusion: PS dental implants appeared to be more effective than PM implants for minimizing the mean marginal vertical and horizontal marginal bone loss during the three-year period. Regardless of which abutment connection was used, the dental implant in the present retrospective investigation exhibited minimal marginal bone remodeling, thus indicating long-term stability. Full article

(This article belongs to the Special Issue Oral Health and Host Related Environmental Factors in Periodontal Status)

► Show Figures

Figure 1

Other

Jump to: Research

9 pages, 267 KiB

Open AccessPerspective

Influence of Adjacent Teeth Absence or Extraction on the Outcome of Non-Surgical Periodontal Therapy

by Jia-Hong Lin, Che-Chang Tu, Yi-Wen Chen, Chen-Ying Wang, Cheing-Meei Liu, Mark Yen-Ping Kuo and Po-Chun Chang

Int. J. Environ. Res. Public Health 2019, 16(22), 4344; https://doi.org/10.3390/ijerph16224344 - 07 Nov 2019

Cited by 5 | Viewed by 2522

Abstract

Background: Extraction of periodontally compromised or strategically non-important teeth is often an integral part of non-surgical periodontal treatment (NSPT). This study evaluated the association between the status of adjacent teeth and the outcome of NSPT on molars. Methods: Charting data of [...] Read more.

Background: Extraction of periodontally compromised or strategically non-important teeth is often an integral part of non-surgical periodontal treatment (NSPT). This study evaluated the association between the status of adjacent teeth and the outcome of NSPT on molars. Methods: Charting data of patients with generalized chronic periodontitis receiving NSPT in 2012–2014 were included. The association between initial clinical parameters and significant clinical improvement, including the reductions of probing pocket depth (PPD) and clinical attachment loss (CAL), in molar teeth with severe periodontitis after NSPT was assessed by a generalized linear model and logistic regression. Results: ≥7 mm PPD and <2 mm gingival recession (REC) at the tooth level, and ≥7 mm PPD, ≥7 mm CAL and <2 mm REC at the site level, were associated with significant clinical improvement. Absence or extraction of an adjacent tooth achieved an additional 0.22–0.23 mm and 0.60–0.83 mm clinical improvement. Among the interproximal sites, ≥7 mm PPD, <2 mm REC, ≥7 mm CAL, <Degree II furcation involvement, and absence of an adjacent tooth were associated with significant clinical improvement. Conclusion: Absence or extraction of teeth during NSPT significantly improves the PPD and CAL of the adjacent periodontal sites of molars. Full article

(This article belongs to the Special Issue Oral Health and Host Related Environmental Factors in Periodontal Status)

Journal Menu

Journal Browser

Oral Health and Host Related Environmental Factors in Periodontal Status

Share This Special Issue

Special Issue Editor

Special Issue Information

Keywords

Published Papers (10 papers)

Research

Other

Further Information

Guidelines

MDPI Initiatives

Follow MDPI