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Oral Diseases: Prevention, Diagnosis and Treatment

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A special issue of International Journal of Environmental Research and Public Health (ISSN 1660-4601).

Deadline for manuscript submissions: 31 December 2024 | Viewed by 11572

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Prof. Dr. Razia Abdool Gafaar G. Khammissa

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Department of Periodontics and Oral Medicine, School of Dentistry, Faculty of Health Sciences, University of Pretoria, Pretoria 0001, South Africa
Interests: periodontics; oral medicine; implantology

Special Issue Information

Dear Colleagues,

Oral medicine is a discipline of dentistry that fosters the link between medical health and dental health. It is a specialty that deals with the diagnosis and non-surgical management of almost all of these oral conditions/lesions. It has been recognized as an important subspecialty of dentistry in many parts of the world; however, there is still a significant gap in the knowledge pertaining to this subspecialty and, consequently, in the management of patients presenting with oral lesions/conditions.

Today, dentists face a number of challenges, including having to manage not only young and healthy patients, but also older patients who have a number of chronic illnesses, and to further exacerbate the challenges they face, these dentists appear to have a lack of awareness and understanding about the oral medicine profession. It is evident that dentists have the potential to improve the quality of and access to oral healthcare, and should be provided with the knowledge and skills to identify and manage patients presenting with oral lesions/conditions and understand the importance of referral and a multidisciplinary approach in the management of these conditions.

The purpose of this Special Issue is to showcase common and important oral lesions or conditions that affect the oral cavity and their prevention, diagnosis and management.

Prof. Dr. Razia Abdool Gafaar G. Khammissa
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Environmental Research and Public Health is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2500 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

oral medicine
oral lesions
oral health
multidisciplinary approach
soft tissue lesions

Published Papers (5 papers)

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Research

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10 pages, 1460 KiB

Open AccessArticle

Incidental Pathologic Findings from Orthodontic Pretreatment Panoramic Radiographs

by Phumzile Hlongwa, Mpule Annah Lerato Moshaoa, Charity Musemwa and Razia Abdool Gafaar Khammissa

Int. J. Environ. Res. Public Health 2023, 20(4), 3479; https://doi.org/10.3390/ijerph20043479 - 16 Feb 2023

Cited by 3 | Viewed by 1796

Abstract

Panoramic radiography is frequently performed for new patients, follow-ups and treatment in progress. This enables dental clinicians to detect pathology, view important structures, and assess developing teeth. The objective of the study was to determine prevalence of incidental pathologic findings (IPFs) from orthodontic pretreatment panoramic radiographs at a university dental hospital. A retrospective cross-sectional review was conducted of pretreatment panoramic radiographs, using data collection sheets with predefined criteria. Demographic data and abnormalities (impacted teeth, widening of periodontal ligament, pulp stones, rotated teeth, missing teeth, unerupted teeth, crowding, spacing, supernumerary teeth, and retained deciduous teeth) were reviewed. SPSS 28.0 was used to analyze data with statistical tests set at a 5% significance level. Results: One hundred panoramic radiographs were analyzed with an age range of 7 to 57 years. The prevalence of IPFs was 38%. A total of 47 IPFs were detected with altered tooth morphology predominantly (n = 17). Most IPFs occurred in males (55.3%), with 44.7% in females. A total of 49.2% were in the maxilla and 50.8% in the mandible. This difference was statistically significant (p < 0.0475). Other abnormalities were detected in 76% of panoramic radiographs; 33 with IPFs and 43 without. A total of 134 other abnormalities detected showed predominantly impacted teeth (n = 49). Most of these abnormalities were in females (n = 77). Conclusions: The prevalence of IPFs was 38%, predominated by altered tooth morphology, idiopathic osteosclerosis, and periapical inflammatory lesions. Detection of IPFs from panoramic radiographs underscored the importance for clinicians to examine them for comprehensive diagnosis and treatment planning, especially in orthodontics. Full article

(This article belongs to the Special Issue Oral Diseases: Prevention, Diagnosis and Treatment)

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13 pages, 1652 KiB

Open AccessArticle

by Ze-Yue Ou-Yang, Yao Feng, Yi-Fan Yang, Ning-Xin Chen, Xiao-Lin Su, Qian Zhang, Meng-Mei Zhong, Jing Hu, Qin Ye, Jie Zhao, Ya-Qiong Zhao, Yun Chen, Li Tan, Qiong Liu, Yun-Zhi Feng and Yue Guo

Int. J. Environ. Res. Public Health 2023, 20(4), 3244; https://doi.org/10.3390/ijerph20043244 - 13 Feb 2023

Viewed by 1434

Abstract

Psychological therapies are important for comprehensive chronic orofacial pain (COFP) treatment. This study is to validate the effects of psychological factors on oral health-related quality of life (OHRQoL) among COFP patients in China. Pain catastrophizing, which is a subjective cognitive emotion used to manage the psychological aspects of pain among COFP patients, was examined in relation to COFP severity and OHRQoL. All 479 participants were recruited in Changsha, Hunan Province, China. Cronbach’s alpha coefficients (0.868–0.960), composite reliability scores (0.924–0.969), and average variance extracted from each construct (0.555–0.753) all indicated a good model fit. Pearson’s correlation analysis showed that age and education status have a positive correlation with COFP severity, pain catastrophizing, and anxiety. COFP severity was related to anxiety, depression, and COFP-OHRQoL. Pain catastrophizing was related to employment status. Anxiety and depression symptoms indirectly mediated the correlation between COFP severity and COFP-OHRQoL. As a second-stage moderator, pain catastrophizing moderated the mediating effects of anxiety symptoms and depression symptoms. Our findings suggest that anxiety, depression, and pain catastrophizing should be evaluated jointly to improve COFP-OHRQoL among COFP patients. This evidence will help therapists to comprehensively treat patients for the best treatment effect. Full article

(This article belongs to the Special Issue Oral Diseases: Prevention, Diagnosis and Treatment)

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Review

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12 pages, 1318 KiB

Open AccessReview

Oral Piercing: A Pretty Risk—A Scoping Review of Local and Systemic Complications of This Current Widespread Fashion

by Giuseppina Malcangi, Assunta Patano, Giulia Palmieri, Lilla Riccaldo, Carmela Pezzolla, Antonio Mancini, Alessio Danilo Inchingolo, Daniela Di Venere, Fabio Piras, Francesco Inchingolo, Gianna Dipalma and Angelo Michele Inchingolo

Int. J. Environ. Res. Public Health 2023, 20(9), 5744; https://doi.org/10.3390/ijerph20095744 - 08 May 2023

Cited by 4 | Viewed by 3141

Abstract

Piercing insertion is a common practice among people of all ages for different reasons (e.g., esthetics, culture, religion). In the oral cavity, the jewel can be placed in the lips, cheeks, tongue, and frenulum. The presence of an oral piercing could cause local and systemic complications in the short term. In the long term, irreversible damage may occur to the hard and soft tissues of the oral cavity. Different authors in the past have produced publications focusing on this issue. This study analyzes 10 published articles sourced from online databases according to the PRISMA flowchart. These articles were chosen from the 501 suitable papers initially found. PubMed, Web of Science, and Scopus were used as the online databases for searching for papers that matched the topic, using the keywords “complication” and “oral piercing”. The purpose of this review is to describe and analyze all possible complications related to the presence of a piercing in the mouth. Local and systemic complications are related to the presence of plaque and localized pathogenic micro-organisms that can spread via the bloodstream, although they rarely occur in patients without predisposing conditions. Maintaining proper oral hygiene and frequent check-ups are essential to avoid the onset of complications. Full article

(This article belongs to the Special Issue Oral Diseases: Prevention, Diagnosis and Treatment)

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10 pages, 748 KiB

Open AccessReview

Tumour Genetic Heterogeneity in Relation to Oral Squamous Cell Carcinoma and Anti-Cancer Treatment

by Gal Feller, Razia Abdool Gafaar Khammissa, Raoul Ballyram, Mia-Michaela Beetge, Johan Lemmer and Liviu Feller

Int. J. Environ. Res. Public Health 2023, 20(3), 2392; https://doi.org/10.3390/ijerph20032392 - 29 Jan 2023

Cited by 6 | Viewed by 1916

Abstract

Oral squamous cell carcinoma (SCC) represents more than 90% of all oral cancers and is the most frequent SCC of the head and neck region. It may affect any oral mucosal subsite but most frequently the tongue, followed by the floor of the mouth. The use of tobacco and betel nut, either smoked or chewed, and abuse of alcohol are the main risk factors for oral SCC. Oral SCC is characterized by considerable genetic heterogeneity and diversity, which together have a significant impact on the biological behaviour, clinical course, and response to treatment and on the generally poor prognosis of this carcinoma. Characterization of spatial and temporal tumour-specific molecular profiles and of person-specific resource availability and environmental and biological selective pressures could assist in personalizing anti-cancer treatment for individual patients, with the aim of improving treatment outcomes. In this narrative review, we discuss some of the events in cancer evolution and the functional significance of driver-mutations in carcinoma-related genes in general and elaborate on mechanisms mediating resistance to anti-cancer treatment. Full article

(This article belongs to the Special Issue Oral Diseases: Prevention, Diagnosis and Treatment)

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Other

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19 pages, 1033 KiB

Open AccessSystematic Review

White Spots: Prevention in Orthodontics—Systematic Review of the Literature

by Assunta Patano, Giuseppina Malcangi, Roberta Sardano, Antonio Mastrodonato, Grazia Garofoli, Antonio Mancini, Alessio Danilo Inchingolo, Daniela Di Venere, Francesco Inchingolo, Gianna Dipalma and Angelo Michele Inchingolo

Int. J. Environ. Res. Public Health 2023, 20(8), 5608; https://doi.org/10.3390/ijerph20085608 - 21 Apr 2023

Cited by 3 | Viewed by 2728

Abstract

Early-stage dental demineralization, called white spots (WS), get their name from the characteristic colour that enamel takes on due to the acid attack of salivary cariogenic bacteria. They are often associated with fixed orthodontic therapy (FOT) and, if left untreated, evolve into caries with repercussions on oral health and dental aesthetics. This review aims to identify the most effective prophylaxis strategies to prevent WS during FOT. The search for the reviewed studies was conducted on the Pubmed, Scopus, and Web of Science databases, selecting English-only articles published in the 5 years from January 2018 to January 2023. The keywords used were “WS” and “fixed orthodontic*”, using “AND” as the Boolean operator. A total of 16 studies were included for qualitative analysis. Prevention begins with maintaining proper oral hygiene; fluoride in toothpaste, mouthwashes, gels, varnishes, and sealants can be added to prophylaxis and used regularly. Using a laser in combination with fluoride helps prevent the occurrence of WS and assists in the repair processes of initial lesions. Further studies are needed to establish international guidelines for preventing WS in orthodontically treated patients. Full article

(This article belongs to the Special Issue Oral Diseases: Prevention, Diagnosis and Treatment)

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