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Diagnostics
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Challenges of Thoracic and Cardiovascular Surgery: From Medical Team-Up and...
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Challenges of Thoracic and Cardiovascular Surgery: From Medical Team-Up and Diagnostic Pitfalls to Operative Skills

A special issue of Diagnostics (ISSN 2075-4418). This special issue belongs to the section "Pathology and Molecular Diagnostics".

Deadline for manuscript submissions: 30 June 2024 | Viewed by 3626

Special Issue Editors

Dr. Mara Carsote

E-Mail Website
Guest Editor
1. Department of Endocrinology, Carol Davila University of Medicine and Pharmacy, 050474 Bucharest, Romania
2. Department of Endocrinology, C.I. Parhon National Institute of Endocrinology, 011863 Bucharest, Romania
Interests: thyroid; adrenal; pituitary; osteoporosis; neuroendocrine tumors; bone; fracture; gynecological endocrinology
Special Issues, Collections and Topics in MDPI journals
Dr. Claudiu Nistor

E-Mail Website
Guest Editor
1. Department 4—Cardio-Thoracic Pathology, Thoracic Surgery II Discipline, Faculty of Medicine, “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania
2. Thoracic Surgery Department, “Dr. Carol Davila” Central Emergency University Military Hospital, 013058 Bucharest, Romania
Interests: thyroid surgery; parathyroid surgery; lung neuroendocrine tumors; lung cancer; minimally invasive surgery; VATS; cervico-mediastinal surgery; thoracic-abdominal surgery; pleuro-pericardial disease; chest wall tumors
Special Issues, Collections and Topics in MDPI journals
Dr. Adrian Ciuche

E-Mail
Guest Editor
Department - Cardio-Thoracic Pathology, Thoracic Surgery II Discipline, “Carol Davila” University of Medicine and Pharmacy & Thoracic Surgery Department, “Dr. Carol Davila” Central Emergency University Military Hospital, 010825 Bucharest, Romania
Interests: lung carcinoid tumor; bronchial sleeve resections; parathyroid adenoma; parathyroidectomy; cervicothoracic junction surgery; thoracoscopy; mediastinoscopy; VATS; cervicotomy; thoracotomy; thoracoplasty; pleurodesis

Special Issue Information

Dear Colleagues,

We invite you to contribute to this Special Issue, which is focused on the challenges, pitfalls and controversies concerning various diseases that involve thoracic and cardiovascular surgery in terms of diagnostic (imaging findings, lymphangiography, electromyography and different procedures such as thyroid biopsy, fine needle aspiration, endobronchial biopsy of fiber optic bronchoscopy, trans-thoracic ultrasound-guided cardiac coaxial needle biopsy, etc.), intra-operative assessments, techniques, and specific skills, and post-operatory pathological and immunohistochemistry reports, management and outcomes.

We are particularly interested, but not exclusively, in diseases such as lung carcinoid, medullary thyroid carcinoma, chylothorax, thymoma, sarcomas, pulmonary hydatid cysts, pleuro-pericardial diseases, neuro-fibrous cervical thoracic tumors and lung cancer.

We thank all the researchers for their contributions to this Special Issue.

Dr. Mara Carsote
Dr. Claudiu Nistor
Dr. Adrian Ciuche
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Diagnostics is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

 

Keywords

  • thoracic surgery
  • cardiovascular surgery
  • medullary thyroid carcinoma
  • lung carcinoid
  • sarcoma
  • VATS
  • vascular sealing devices
  • biopsy

Published Papers (1 paper)

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Review

26 pages, 3961 KiB  
Review
Sternum Metastases: From Case-Identifying Strategy to Multidisciplinary Management
by Mara Carsote, Dana Terzea, Florina Vasilescu, Anca-Pati Cucu, Adrian Ciuche and Claudiu Nistor
Diagnostics 2023, 13(16), 2698; https://doi.org/10.3390/diagnostics13162698 - 17 Aug 2023
Cited by 1 | Viewed by 3018
Abstract
We aimed to overview the most recent data on sternal metastases from a multidisciplinary approach (diagnosis strategies, outcome, and histological reports). This narrative review based on a PubMed search (between January 2020 and 22 July 2023) using key words such as “sternal”, “manubrium”, [...] Read more.
We aimed to overview the most recent data on sternal metastases from a multidisciplinary approach (diagnosis strategies, outcome, and histological reports). This narrative review based on a PubMed search (between January 2020 and 22 July 2023) using key words such as “sternal”, “manubrium”, and “metastasis” within the title and/or abstract only included original papers that specifically addressed secondary sternal spreading of cancer in adults, for a total of 48 original articles (14 studies and 34 single case reports). A prior unpublished case in point is also introduced (percutaneous incisional biopsy was used to address a 10 cm sternal tumour upon first admission on an apparently healthy male). The studies (n = 14) may be classified into one of three groups: studies addressing the incidence of bone metastases (including sternum) amid different primary cancers, such as prostate cancer (N = 122 with bone metastases, 83% of them with chest wall metastases), head and neck cancers (N = 3620, 0.8% with bone metastases, and 10.34% of this subgroup with sternum involvement); and glioblastoma (N = 92 with bone metastases, 37% of them with non-vertebral metastases, including the sternum); assessment cohorts, including breast cancer (N = 410; accuracy and sensitivity of PET/CT vs. bone scintigraphy is superior with concern to sternum spreading) and bone metastases of unknown origin (N = 83, including a subgroup with sternum metastases; some features of PET/CT help the differentiation with multiple myeloma); and cohorts with various therapeutic approaches, such as palliative arterial embolization (N = 10), thymic neuroendocrine neoplasia (1/5 detected with sternum metastases), survival rates for sternum metastases vs. non-sternum chest wall involvement (N = 87), oligo-metastatic (sternal) breast cancer (3 studies, N = 16 for all of them), oligo-metastatic head and neck cancer (N = 81), conformal radiotherapy (N = 24,215, including an analysis on sternum spreading), and EBRT followed by MR-HIFU (N = 6). Core data coming from the isolated case reports (N = 34) showed a female to male ratio of 1.6; the females’ ages were between 34 and 80 (mean of 57.28) and the males’ ages varied between 33 and 79 (average of 58.78) years. The originating tumour profile revealed that the most frequent types were mammary (N = 8, all females) and thyroid (N = 9, both women and men), followed by bladder (N = 3), lung (N = 2), and kidney (N = 2). There was also one case for each of the following: adenoid cystic carcinoma of the jaw, malignant melanoma, caecum MiNEN, a brain and an extracranial meningioma, tongue carcinoma, cholangiocarcinoma, osteosarcoma, and hepatocellular carcinoma. To our knowledge, this is the most complex and the largest analysis of prior published data within the time frame of our methods. These data open up new perspectives of this intricate, dynamic, and challenging domain of sternum metastases. Awareness is a mandatory factor since the patients may have a complex multidisciplinary medical and/or surgical background or they are admitted for the first time with this condition; thus, the convolute puzzle will start from this newly detected sternal lump. Abbreviations: N = number of patients; n = number of studies; PET/CT = positron emission tomography/computed tomography; EVRT = external beam radiotherapy; MR-HIFU = magnetic resonance-guided high-intensity focused ultrasound; MiNEN = mixed neuroendocrine-non-neuroendocrine tumour. Full article
(This article belongs to the Special Issue Challenges of Thoracic and Cardiovascular Surgery: From Medical Team-Up and Diagnostic Pitfalls to Operative Skills)
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