Risk Factors and Biomarkers for Cardiovascular Disease: 2nd Edition

A special issue of Diagnostics (ISSN 2075-4418). This special issue belongs to the section "Pathology and Molecular Diagnostics".

Deadline for manuscript submissions: closed (31 December 2023) | Viewed by 1612

Special Issue Editors


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Guest Editor
Department of Pathophysiology, “Grigore T. Popa” University of Medicine and Pharmacy, 16 Universitatii Street, 700115 Iasi, Romania
Interests: cardiovascular diseases; metabolic diseases; diabetes mellitus; hypercoagulability; antioxidants
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor
Department of Internal Medicine, “Grigore T. Popa” University of Medicine and Pharmacy, 16 Universitatii Street, 700115 Iasi, Romania
Interests: cardiovascular disease; atherosclerosis; arterial thrombosis; venous thrombosis; anticoagulants; hereditary thrombophilia; inflammation
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor
Department of Pathophysiology, “Grigore T. Popa” University of Medicine and Pharmacy, 16 Universitatii Street, 700115 Iasi, Romania
Interests: cardiovascular diseases; hypercoagulability; acute cardiac care; noninvasive cardiovascular imaging techniques
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Cardiovascular disease is still the leading cause of morbidity and mortality worldwide despite the great diagnostic and therapeutic progress made in recent decades. The intervention on cardiovascular risk factors is seen as the best long-term solution to improve the outcome of these patients. Therefore, their identification and appropriate therapeutic approach are of the utmost importance.

Some of them are behavioural risk factors, such as unhealthy diet, physical inactivity, tobacco use, and excessive alcohol consumption. Although it is not difficult to correct them, their prevalence remains high because the population is not fully aware of their harmful effect on health. The continuous and long-term action of behavioural risk factors is associated with overweight and obesity, atherogenic dyslipidemia, diabetes, and hypertension, all of which are strong risk factors for cardiovascular disease. The risk of stroke, ischemic heart disease, peripheral artery disease, heart failure, and death that an individual has, increases exponentially as risk factors accumulate because they potentiate each other and accelerate target organ damage.

Although there are many different risk factors that increase the likelihood of developing  cardiovascular disease, they are largely preventable. By implementing a healthy lifestyle and appropriate pharmacological intervention, we can improve the longevity and quality of life of millions of people around the world.

We invite you to share your knowledge and experience. Original and review papers that address cardiovascular risk factors in all aspects, from cellular and molecular mechanisms, and pathophysiological links to problems of diagnosis, treatment, and monitoring are welcome. Only a strong team can have results that matter!

Prof. Dr. Manuela Ciocoiu
Dr. Minerva Codruta Badescu
Dr. Iris Bararu-Bojan
Guest Editors

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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

 

Keywords

  • cardiovascular risk factors
  • hypertension
  • dyslipidemia
  • overweight
  • obesity
  • diabetes mellitus
  • metabolic syndrome
  • atherosclerosis
  • physical inactivity
  • biomarkers
  • cardiovascular disease

Published Papers (1 paper)

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Research

11 pages, 646 KiB  
Article
Ambulatory Blood Pressure Monitoring as a Useful Tool in the Cardiological Assessment of Pancreas Transplant Recipients with Type 1 Diabetes
by Małgorzata Buksińska-Lisik, Przemysław Jerzy Kwasiborski, Robert Ryczek, Wojciech Lisik and Artur Mamcarz
Diagnostics 2023, 13(17), 2724; https://doi.org/10.3390/diagnostics13172724 - 22 Aug 2023
Viewed by 632
Abstract
Having the appropriate tools to identify pancreas recipients most susceptible to coronary artery disease (CAD) is crucial for pretransplant cardiological assessment. The aim of this study is to evaluate the association between blood pressure (BP) indices provided by ambulatory blood pressure monitoring (ABPM) [...] Read more.
Having the appropriate tools to identify pancreas recipients most susceptible to coronary artery disease (CAD) is crucial for pretransplant cardiological assessment. The aim of this study is to evaluate the association between blood pressure (BP) indices provided by ambulatory blood pressure monitoring (ABPM) and the prevalence of CAD in pancreas transplant candidates with type 1 diabetes (T1D). This prospective cross-sectional study included adult T1D patients referred for pretransplant cardiological assessment in our center. The study population included 86 participants with a median age of 40 (35–46) years. In multivariate logistic regression analyses, after adjusting for potential confounding factors, higher 24 h BP (systolic BP/diastolic BP/pulse pressure) (OR  =  1.063, 95% CI 1.023–1.105, p = 0.002/OR = 1.075, 95% CI 1.003–1.153, p = 0.042/OR = 1.091, 95 CI 1.037–1.147, p = 0.001, respectively) and higher daytime BP (systolic BP/diastolic BP/pulse pressure) (OR  =  1.069, 95% CI 1.027–1.113, p = 0.001/OR = 1.077, 95% CI 1.002–1.157, p = 0.043/OR = 1.11, 95% CI 1.051–1.172, p = 0.0002, respectively) were independently and significantly associated with the prevalence of CAD. Daytime pulse pressure was the strongest indicator of the prevalence of CAD among all analyzed ABPM parameters. ABPM can be used as a valuable tool to identify pancreas recipients who are most susceptible to CAD. We suggest the inclusion of ABPM in pretransplant cardiac screening in type 1 diabetes patients eligible for pancreas transplantation. Full article
(This article belongs to the Special Issue Risk Factors and Biomarkers for Cardiovascular Disease: 2nd Edition)
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