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Diagnostics
Special Issues
Recent Advances in Gynecologic Oncology: From Diagnosis to Prognosis
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Recent Advances in Gynecologic Oncology: From Diagnosis to Prognosis

A special issue of Diagnostics (ISSN 2075-4418). This special issue belongs to the section "Medical Imaging and Theranostics".

Deadline for manuscript submissions: closed (31 March 2024) | Viewed by 706

Special Issue Editor

Dr. Simone Ferrero

E-Mail Website
Guest Editor
Academic Unit of Obstetrics and Gynecology, IRCCS Ospedale Policlinico San Martino, University of Genova, 16132 Genova, Italy
Interests: laparoscopy; minimally invasive surgery; ultrasonography; endometriosis; uterine fibroids; gynecological oncology
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Cancers of the female genital organs are known explicitly as gynecological cancers, including tubo-ovarian cancer, uterine and cervical cancer, vaginal cancer, and vulvar cancer.

The optimal screening methods for gynecologic cancers are still being investigated. Cervical cancer is the only gynecologic malignancy for which a screening modality is widely accepted and recommended to all women. Surgery is the primary treatment for several gynecological cancer patients. However, further treatment (adjuvant therapy and/or maintenance therapy) is required in some patients. Additionally, in patients with advanced or recurrent diseases, the outcome may be disappointing.

This Special Issue will publish reviews and original papers on detection, prevention, diagnosis, and treatment of gynecologic malignancies. Therefore, gynecologists, medical oncologists, radiation oncologists, radiologists, pathologists, and research scientists with a special interest in gynecological oncology are invited to submit manuscripts for publication in this Special Issue.

Dr. Simone Ferrero
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Diagnostics is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • endometriosis
  • ovarian cancer
  • cervical cancer
  • gynecologic endoscopy
  • gynecologic imaging

Published Papers (1 paper)

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Research

11 pages, 994 KiB  
Article
Radiation-Related Fractures after Radical Radiotherapy for Cervical and Endometrial Cancers: Are There Any Differences?
by Hana Malikova, Katarina Nadova, Klaudia Reginacova, Karin Kremenova and Lukas Rob
Diagnostics 2024, 14(8), 810; https://doi.org/10.3390/diagnostics14080810 - 12 Apr 2024
Viewed by 339
Abstract
In this study, we reviewed CT/MRI scans and studied the rates of radiation-related fractures in subjects treated for cervical cancer (CC, 63 subjects) by radical radiotherapy (RT) and in subjects treated for endometrial cancer (EC, 64 subjects) by radical surgery and RT. The [...] Read more.
In this study, we reviewed CT/MRI scans and studied the rates of radiation-related fractures in subjects treated for cervical cancer (CC, 63 subjects) by radical radiotherapy (RT) and in subjects treated for endometrial cancer (EC, 64 subjects) by radical surgery and RT. The differences between bone density measured in L1 on pretreatment CT, age and body mass index (BMI) were evaluated. Despite significant differences in RT total dose, age, BMI, etc., between both groups, the rate of radiation-related fractures was similar: 28.6% of CC versus 26.6% of EC subjects. CC subjects with fractures were significantly older (62.4 ± 10.1 vs. 49.0 ± 12.4 years; p < 0.001), and their bone densities were significantly lower (106.3 ± 40.0 vs. 168.2 ± 49.5 HU; p < 0.001); no difference in BMI was found. EC subjects with fractures were without significant difference in age but had significantly lower bone densities (103.8 ± 29.0 vs. 133.8 ± 42.3 HU; p = 0.009) and BMIs (26.1 ± 4.9 vs. 31.8 ± 6.9 kg/m2; p = 0.003). Bone density strongly correlated with age (r = −0.755) only in CC subjects. Subjects with fractures from both groups had similarly low bone densities (106.3 ± 40.0 vs. 103.8 ± 29.0 HU; p = 0.829); however, no correlation between bone density and BMI was found. The rate of radiation-related fractures in both groups was clearly associated only with low pretreatment bone density, reflecting osteoporosis. Full article
(This article belongs to the Special Issue Recent Advances in Gynecologic Oncology: From Diagnosis to Prognosis)
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