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Dentistry Journal
Special Issues
Salivary Medicine and Regeneration of Salivary Glands
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Salivary Medicine and Regeneration of Salivary Glands

A special issue of Dentistry Journal (ISSN 2304-6767).

Deadline for manuscript submissions: closed (31 August 2020) | Viewed by 6197

Special Issue Editor

Dr. Mihnea Ioan Nicolescu

E-Mail Website
Guest Editor
Department of Histology, University of Medicine and Pharmacy “Carol Davila”, 050474 Bucharest, Romania
Interests: salivary regeneration; medical education; interstitial cells; telocytes; radiobiology

Special Issue Information

Dear Colleagues,

Saliva is a biological fluid which maintains oral health (protecting teeth and tongue) while also taking an active part in digestion, taste sensing and antimicrobial mechanisms. A major clinical problem is the lack of saliva caused by various malfunctions of salivary glands. Repairing or regenerating the salivary glands by restoring a healthy cellular microenvironment is regarded as an appealing alternative to the current limited palliative-only treatments (sialagogues or artificial saliva). Salivary glands are known to possess an intrinsic recovery potential, which allows them to self-repair after experimental induced atrophy. The regeneration capability of salivary glands is among top research topics in salivary research.
Salivary biomarker data, as well as developmental pathways findings, are helping to rapidly piece together the puzzle of salivary gland regeneration.
In this Special Issue, we intend to sum up the latest discoveries in the field in order to serve as a useful tool for researchers that are interested in both saliva and regenerative medicine.

Dr. Mihnea-Ioan Nicolescu
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Dentistry Journal is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • Saliva
  • Biomarkers
  • Salivary glands
  • Regenerative medicine

Published Papers (1 paper)

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Research

7 pages, 629 KiB  
Article
Reliability of Screening Methods to Diagnose Oral Dryness and Evaluate Saliva Secretion
by Takaharu Goto, Takahiro Kishimoto, Yuki Iwawaki, Keiko Fujimoto, Yuichi Ishida, Megumi Watanabe, Kan Nagao and Tetsuo Ichikawa
Dent. J. 2020, 8(3), 102; https://doi.org/10.3390/dj8030102 - 02 Sep 2020
Cited by 3 | Viewed by 5731
Abstract
In this study, we evaluated the reliability and reproducibility of widely implemented salivary flow rate and oral dryness tests. In experiment 1, twenty young and healthy Japanese participants volunteered to participate. For each participant, the oral moisture (OM) level, unstimulated whole saliva volume [...] Read more.
In this study, we evaluated the reliability and reproducibility of widely implemented salivary flow rate and oral dryness tests. In experiment 1, twenty young and healthy Japanese participants volunteered to participate. For each participant, the oral moisture (OM) level, unstimulated whole saliva volume (U-WSV), and stimulated whole saliva volume (S-WSV) were measured at the same time on two separate days. In experiment 2, twenty-seven patients who were over 65 years of age volunteered to participate. The OM level and U-WSV were measured at the same time on two separate days. In Experiment 1, the intra-class correlation coefficients (ICCs) corresponding to the S-WSV, U-WSV, and OM level were 0.23, 0.28, and 0.16, respectively, for the young participants. In Experiment 2, the ICCs corresponding to the U-WSV/spitting and OM level were 0.83 and 0.12, respectively, for the older participants. The results of Bland–Altman analysis confirmed the absence of systematic error, with the exception of the OM level results in Experiment 2, which indicated systematic bias. In conclusion, we believe that there is currently no consistent and reliable screening test for assessing salivary flow rate and oral dryness, although the spitting test was determined to be highly reliable. Full article
(This article belongs to the Special Issue Salivary Medicine and Regeneration of Salivary Glands)
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