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Current Oncology
Special Issues
Quality of Life and Satisfaction with Outcome among Cancer Survivors
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Quality of Life and Satisfaction with Outcome among Cancer Survivors

A special issue of Current Oncology (ISSN 1718-7729). This special issue belongs to the section "Palliative and Supportive Care".

Deadline for manuscript submissions: closed (31 December 2023) | Viewed by 2200

Special Issue Editor

Dr. Sinziana Dumitra

E-Mail Website
Guest Editor
Department of Surgical Oncology, McGill University Health Centre, Montréal, QC H4A 3J1, Canada
Interests: cancer care improvement; Improving access and quality of cancer care; retroperitoneal sarcoma; HIPEC; melanoma

Special Issue Information

Dear Colleagues,

With an improvement in the efficacy of cancer treatments and increase in patient survival, there is a rising interest and focus on long-term quality of life and patient satisfaction with outcomes among cancer survivors. Exciting avenues of research in this arena have shown the impact that a cancer diagnosis and treatments can have on patients and their families. As survivorship improves, we are starting to see the long-term effects of cancer treatments whether they be radiotherapy, surgery, chemotherapy, immunotherapy, or targeted therapy. Understating the impact on quality of life and the real-life consequences to our patients is paramount in providing adequate support, decreasing distress, and improving outcomes.

In this Special Issue, original research articles and reviews are welcome. Research areas may include (but are not limited to) the following:

  1. Long-term side effects of cancer treatments (especially new therapies)
  2. Designing a successful survivorship program
  3. Patient satisfaction 
  4. Incorporating quality of life concerns in consent to cancer treatments
  5. Addressing distress in cancer patients
  6. Barriers in return to the workforce after a cancer diagnosis
  7. Fertility preservation and outcomes
  8. Long-term financial toxicity of cancer treatments
  9. Survivorship care plan
  10. Tools for improving quality of life and satisfaction with treatment outcomes among cancer survivors

I look forward to receiving your contributions.

Dr. Sinziana Dumitra
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Current Oncology is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • quality of life
  • cancer care
  • outcome among cancer survivors
  • cancer survivorship

Published Papers (2 papers)

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Research

16 pages, 1133 KiB  
Article
Income Disparities in Survival and Receipt of Neoadjuvant Chemotherapy and Pelvic Lymph Node Dissection for Muscle-Invasive Bladder Cancer
by Ryan M. Antar, Vincent E. Xu, Oluwafolajimi Adesanya, Arthur Drouaud, Noah Longton, Olivia Gordon, Kirolos Youssef, Jad Kfouri, Sarah Azari, Sean Tafuri, Briana Goddard and Michael J. Whalen
Curr. Oncol. 2024, 31(5), 2566-2581; https://doi.org/10.3390/curroncol31050192 - 2 May 2024
Viewed by 645
Abstract
Background: Muscle-invasive bladder cancer (MIBC) is a potentially fatal disease, especially in the setting of locally advanced or node-positive disease. Adverse outcomes have also primarily been associated with low-income status, as has been reported in other cancers. While the adoption of neoadjuvant cisplatin-based [...] Read more.
Background: Muscle-invasive bladder cancer (MIBC) is a potentially fatal disease, especially in the setting of locally advanced or node-positive disease. Adverse outcomes have also primarily been associated with low-income status, as has been reported in other cancers. While the adoption of neoadjuvant cisplatin-based chemotherapy (NAC) followed by radical cystectomy (RC) and pelvic lymph node dissection (PLND) has improved outcomes, these standard-of-care treatments may be underutilized in lower-income patients. We sought to investigate the economic disparities in NAC and PLND receipt and survival outcomes in MIBC. Methods: Utilizing the National Cancer Database, a retrospective cohort analysis of cT2-4N0-3M0 BCa patients with urothelial histology who underwent RC was conducted. The impact of income level on overall survival (OS) and the likelihood of receiving NAC and PLND was evaluated. Results: A total of 25,823 patients were included. This study found that lower-income patients were less likely to receive NAC and adequate PLND (≥15 LNs). Moreover, lower-income patients exhibited worse OS (Median OS 55.9 months vs. 68.2 months, p < 0.001). Our findings also demonstrated that higher income, treatment at academic facilities, and recent years of diagnosis were associated with an increased likelihood of receiving standard-of-care modalities and improved survival. Conclusions: Even after controlling for clinicodemographic variables, income independently influenced the receipt of standard MIBC treatments and survival. Our findings identify an opportunity to improve the quality of care for lower-income MIBC patients through concerted efforts to regionalize multi-modal urologic oncology care. Full article
(This article belongs to the Special Issue Quality of Life and Satisfaction with Outcome among Cancer Survivors)
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15 pages, 1295 KiB  
Article
Head and Neck Cancer: A Study on the Complex Relationship between QoL and Swallowing Function
by Daniel Strüder, Johanna Ebert, Friederike Kalle, Sebastian P. Schraven, Lennart Eichhorst, Robert Mlynski and Wilma Großmann
Curr. Oncol. 2023, 30(12), 10336-10350; https://doi.org/10.3390/curroncol30120753 - 6 Dec 2023
Viewed by 1163
Abstract
Head and neck squamous cell carcinoma (HNSCC) is linked to significant morbidity, adversely affecting survival and functional capacity. Post-treatment challenges such as pain, dysphonia, and dysphagia are common, prompting increased attention in survivorship research. Quality of Life (QoL) questionnaires, especially the MD Anderson [...] Read more.
Head and neck squamous cell carcinoma (HNSCC) is linked to significant morbidity, adversely affecting survival and functional capacity. Post-treatment challenges such as pain, dysphonia, and dysphagia are common, prompting increased attention in survivorship research. Quality of Life (QoL) questionnaires, especially the MD Anderson Dysphagia Inventory (MDADI), are prevalent outcome measures in clinical studies but often lack parallel objective swallowing function evaluations, leading to potential outcome discrepancies. This study aimed to illuminate the relationship between subjective QoL (EQ-5D-5L and MDADI) measures and objective swallowing function (evaluated via Fiberoptic Endoscopic Evaluation of Swallowing, FEES) in patients with HNSCC. The analysis revealed a notable discordance between objective measures of swallowing function, such as the Penetration–Aspiration Scale (PAS) and residue ratings in the vallecula or piriform sinus, and patients’ subjective QoL assessments (p = 0.21). Despite the lack of correlation, swallowing-related QoL, as measured by the MDADI, was more indicative of disease severity than generic QoL assessments. Generic QoL scores did not demonstrate substantial variation between patients. In contrast, MDADI scores significantly declined with advancing tumor stage, multimodal therapy, and reliance on feeding tubes. However, the clinical significance of this finding was tempered by the less than 10-point difference in MDADI scores. The findings of this study underline the limitations of QoL measures as standalone assessments in patients with HNSCC, given their reliance on patient-perceived impairment. While subjective QoL is a crucial aspect of evaluating therapeutic success and patient-centric outcomes, it may fail to capture critical clinical details such as silent aspirations. Consequently, QoL assessments should be augmented by objective evaluations of swallowing function in clinical research and practice to ensure a holistic understanding of patient well-being and treatment impact. Full article
(This article belongs to the Special Issue Quality of Life and Satisfaction with Outcome among Cancer Survivors)
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