Editorial Board Members’ Collection Series: Recent Advancements in Malignant Parotid Tumors

A special issue of Current Oncology (ISSN 1718-7729). This special issue belongs to the section "Head and Neck Oncology".

Deadline for manuscript submissions: closed (30 September 2023) | Viewed by 2281

Special Issue Editors


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Guest Editor
Medical Oncology Unit, San Giovanni di Dio Hospital, 80027 Frattamaggiore, Naples, Italy
Interests: head and neck cancer; brain tumor; clinical research; chemotherapy; immunotherapy; target therapy; rare cancer; quality of life; patient centered care
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Guest Editor
Department of Radiodiagnostics and Interventional Imaging, Polyclinics ELSAN Group, PolyClinics Les Fleurs, Quartier Quiez, 83189 Ollioules, France
Interests: central venous catheter port; PICC line; superior vena cava syndrome; head and neck cancer; thyroid malignancy; fine needle aspiration cytology; core needle biopsy; thoracic oncology
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Salivary gland malignancies are rare, heterogeneous, and diverse, constituting 1–3% of head–neck tumors. Clinical course varies according to a diverse range of histological and clinical behaviors, ranging from indolent, slow-growing adenoid cystic carcinoma to rapidly progressive, possibly fatal, salivary ductal carcinoma.

In this Special Issue on “Editorial Board Members’ Collection Series: Recent Advancements in Malignant Parotid Tumors”, we encourage original research or review articles on the wide range of topics related to parotid tumor, from epidemiology histology and genetic translocation to clinical management, including surgery and radiation therapy, chemotherapy, and novel therapeutics, such as molecular targeted therapies.

Dr. Raffaele Addeo
Dr. Pierre Yves Marcy
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Current Oncology is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • parotid
  • recurrence
  • salivary glands
  • histology
  • molecular biology
  • chemotherapy
  • radiation therapy
  • surgery
  • target therapy

Published Papers (1 paper)

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Research

13 pages, 274 KiB  
Article
Survival in Patients with Primary Parotid Gland Carcinoma after Surgery—Results of a Single-Centre Study
by Filippo Carta, Mauro Bontempi, Daniele De Seta, Simone Corrias, Melania Tatti, Valeria Marrosu, Cinzia Mariani, Clara Gerosa, Sanjana Ashik Shetty, Matteo Atzeni, Christina Buckley, Andrea Figus and Roberto Puxeddu
Curr. Oncol. 2023, 30(3), 2702-2714; https://doi.org/10.3390/curroncol30030204 - 23 Feb 2023
Cited by 1 | Viewed by 1603
Abstract
This study aims to analyse a single-centre cohort series of patients who underwent parotidectomy for primary malignant parotid tumours. A retrospective chart review of 64 consecutive patients treated from November 2010 to March 2022 was performed. Outcomes were analysed by Kaplan-Meier curves. Sixty-four [...] Read more.
This study aims to analyse a single-centre cohort series of patients who underwent parotidectomy for primary malignant parotid tumours. A retrospective chart review of 64 consecutive patients treated from November 2010 to March 2022 was performed. Outcomes were analysed by Kaplan-Meier curves. Sixty-four patients with a primary parotid malignancy were included in the study, with one bilateral case in this cohort. Patients were classified as stage I–II in 39 cases and stage III–IV in 26 cases. The five-year overall survival (OS), disease-specific survival (DSS), local relapse-free survival (LRFS), and distant metastasis-free survival (DMFS) rates were 78.4%, 89%, 92.5%, and 87.1%, respectively. Univariate analysis showed that high-risk histology, stage IV disease, lymphovascular invasion, perineural invasion, node metastasis, skin involvement, facial nerve involvement, and positive or close margins were risk factors associated with poorer outcomes. At present, the best evidence suggests that radical surgery should be the standard approach, and adjuvant therapy, in terms of radiotherapy/chemoradiotherapy, is recommended in patients with risk factors. Full article
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