Atmospheric Plasma Treatment or Assistance for Functional Coatings or Biomedical Applications

A special issue of Coatings (ISSN 2079-6412). This special issue belongs to the section "Plasma Coatings, Surfaces & Interfaces".

Deadline for manuscript submissions: closed (31 July 2022) | Viewed by 3360

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Guest Editor
Department of Materials Science and Engineering, National Cheng Kung University, Tainan, Taiwan
Interests: nanofabricated surfaces; mechanics of biomaterials; plasma medicine; cell-surface interactions; micro-contact imprinting; plasma generation
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Special Issue Information

Dear Colleagues,

Plasma is an ionized form of gas composed of charged particles, electronically excited atoms and molecules, radicals, and UV photons. There are a lot of applications based on the variability of the excited species. Atmospheric plasma devices have been designed in various forms for varied applications such as surface cleaning, functional coatings, surface modification, and particle synthesis. On the other hand, a nonthermal atmospheric microplasma device has also been designed for low-temperature (<40 °C) applications such as the treatment of chronic wounds and pathogen-induced diseases on the skin, the suppression of cancer cells, and the influence of medically relevant cellular processes. This Special Issue aims to collect cutting-edge research on the applications of atmospheric plasma devices in functional coatings and biomedicine. Of particular interest are plasma devices that may be used in the non-invasive treatment of skin disease or as auxiliaries for minimally invasive surgery.

Prof. Dr. Jiunn-Der Liao
Guest Editor

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Keywords

  • atmospheric plasma
  • atmospheric nonthermal microplasma
  • functional coatings
  • pathogen suppression or removal
  • cell or skin treatment

Published Papers (2 papers)

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Research

16 pages, 6811 KiB  
Article
Plasma-Sprayed Hydroxyapatite Coatings and Their Biological Properties
by Szymon Kowalski, Weronika Gonciarz, Radosław Belka, Anna Góral, Magdalena Chmiela, Łukasz Lechowicz, Wiesław Kaca and Wojciech Żórawski
Coatings 2022, 12(9), 1317; https://doi.org/10.3390/coatings12091317 - 09 Sep 2022
Cited by 9 | Viewed by 2188
Abstract
Air plasma spraying (APS) is a common method of producing hydroxyapatite (HA) coatings for alloprosthetic implants. Modification of HA spraying potentially may diminish the risk of inflammation and local infection during bone implantation. Titanium implants were HA coated with different deposition process parameters. [...] Read more.
Air plasma spraying (APS) is a common method of producing hydroxyapatite (HA) coatings for alloprosthetic implants. Modification of HA spraying potentially may diminish the risk of inflammation and local infection during bone implantation. Titanium implants were HA coated with different deposition process parameters. HA powder was deposited using APS with axial powder injection at three different distances (100, 120, and 140 mm). The surface morphology of each implant was examined and the direct contact cytotoxicity of each HA coating was evaluated according to norm ISO 10993 5:2009. The response of monocytes to HA was assessed via the activation of transcription nuclear factor. All coatings had a lamellar structure. HA sprayed at a distance of 120 mm showed the highest roughness and little phase change. The analysis of the results of the conducted research showed that plasma-spraying distance during the HA coating process had a negligible impact on biocompatibility. The results obtained for a distance of 120 mm showed a slight increase in the biological properties tested. Moreover, HA coatings sprayed at different distances were not cytotoxic and did not stimulate the NF-kB. Bare titanium was less susceptible to colonization by Staphylococcus aureus than HA-coated surfaces. HA constitutes a potentially good, low-cost, non-cytotoxic material for joint prostheses. Full article
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14 pages, 4387 KiB  
Article
Non-Thermal Reactive N2/He Plasma Exposure to Inhibit Epithelial Head and Neck Tumor Cells
by Chih-Ying Wu, Jiunn-Der Liao, Chang-Han Chen, Han Lee, Shyh-Hau Wang, Bernard Haochih Liu, Cheng-Yi Lee, Pei-Lin Shao and Enya Li
Coatings 2021, 11(11), 1284; https://doi.org/10.3390/coatings11111284 - 22 Oct 2021
Cited by 1 | Viewed by 1687
Abstract
The traditional therapy for head and neck cancer patients has several side effects. Hence, regular follow-up care is usually required. Recently, non-thermal micro-plasma was applied to inactivate cancer cells. Such a physical method provides localized energy and reactive oxygen/nitrogen species (ROS/RNS). In this [...] Read more.
The traditional therapy for head and neck cancer patients has several side effects. Hence, regular follow-up care is usually required. Recently, non-thermal micro-plasma was applied to inactivate cancer cells. Such a physical method provides localized energy and reactive oxygen/nitrogen species (ROS/RNS). In this study, the ability of non-oxygen N2/He micro-plasma to inactivate four pharynx squamous carcinomatous cells, namely SAS, CAL 27, FaDu, and Detroit 562, under different exposure durations is evaluated. The four cell lines were affected with regard to proliferation, reduction, and apoptosis-related DNA damage, implying that the cell medium is critical in plasma–cell interaction. This is expected to be a promising method for head and neck cancer cell suppression through plasma-initiated ROS/RNS species under a suitable exposure time. Full article
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